Piroxicam and pregnancy?

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Stef17
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Date Joined Feb 2003
Total Posts : 1811
   Posted 4/4/2008 10:30 AM (GMT -7)   
Does anyone have any experience with this drug and being pregnant. I see that it is Category C, but I would love to hear from anyone who has taken this while pregnant.  Thank you!!!

Ducky
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Date Joined Mar 2005
Total Posts : 3199
   Posted 4/6/2008 3:29 PM (GMT -7)   
Hi there Stef, I have taken Piroxicam, but not while pregnant.. it is my understanding though, that it is not reccommended.. are you on it and pregnant?
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Stef17
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Date Joined Feb 2003
Total Posts : 1811
   Posted 4/6/2008 8:14 PM (GMT -7)   
No, I'm not. Fortunately I'm on remicade! :) A friend with moderately severe arthritis just got put on it and she wants to start her family. She told her doc this and doc put her on Piroxicam. I hadn't heard of it, so I thought I'd ask around. It shows category C, so I didn't think it was such a great choice of meds. I thought I'd see if anyone here had been on it while preggo or had heard of it at least.

Ducky
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Date Joined Mar 2005
Total Posts : 3199
   Posted 4/7/2008 7:55 AM (GMT -7)   
Did she ask him why he put her on that instead of something else? Let me do some more research.. poor thing.. what a good friend you are to try and find out some info for her!
Moderator of Arthritis Forum
Confirmed Diagnosis of - Psoriatic Arthritis/Spondylitis/Graves Disease/GERD/Scoliosis/Hiatal Hernia/Graves Disease of the Eyes/Chronic UTIs/Migraines/Hypertension
Current Meds -  Enbrel/Prilosec/Synthroid/Nitrofurantoin/Midrin/HYZAAR
Past Meds - Inderal/PTU/Prednisone/Voltaren/Feldene/Mobic/Cortisone and Steroid Shots


Stef17
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Date Joined Feb 2003
Total Posts : 1811
   Posted 4/7/2008 1:34 PM (GMT -7)   
Thanks! I was trying to dig around on the internet, but I didn't find a whole lot. Maybe I'm not looking in the right places. I don't think she asked the doc why about the med. She's not been "sick" long enough to be MD-savvy. She also hasn't totally learned to stick up for herself yet. BUT, for now she's taking the piroxicam and thinking that she'll stop the minute she finds out she's pregnant. I never took Piroxicam and I just don't know what's out there or what would be a better option for her (if any). I'll sincerely appreciate any info you might find! THANKS A MILLION!!!

Ducky
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Date Joined Mar 2005
Total Posts : 3199
   Posted 4/7/2008 6:39 PM (GMT -7)   
Hey Stef.. I have had computer issues today.. plus I've been out.. so I haven't been able to find anything yet.. but I will post something within the next day or so.. you are a great friend!
Moderator of Arthritis Forum
Confirmed Diagnosis of - Psoriatic Arthritis/Spondylitis/Graves Disease/GERD/Scoliosis/Hiatal Hernia/Graves Disease of the Eyes/Chronic UTIs/Migraines/Hypertension
Current Meds -  Enbrel/Prilosec/Synthroid/Nitrofurantoin/Midrin/HYZAAR
Past Meds - Inderal/PTU/Prednisone/Voltaren/Feldene/Mobic/Cortisone and Steroid Shots


Ducky
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Date Joined Mar 2005
Total Posts : 3199
   Posted 4/7/2008 11:15 PM (GMT -7)   
Hey Stef.. me again.. ok.. this is what I've found out.. If your friend does get pregnant while on this med, she needs to tell her doc as soon as possible.. the reason why is 'cause in late pregnancy, as with other NSAIDs, Piroxicam or FELDENE should be avoided because it may cause premature closure of the ductus arteriosus.. Ductus arteriosus is a key arterial shunt (ductus) in fetal life. Before birth, blood pumped from the heart through the pulmonary artery toward the lungs is shunted into the aorta. This arterial shunt is a short vessel called the ductus arteriosus. When the shunt is open, it is said to be patent.

The ductus arteriosus usually closes at or shortly after birth, permitting blood from that moment on to course from the heart directly to the lungs. However, if the ductus arteriosus remains open (patent), flow reverses and blood from the aorta is shunted left-to-right into the pulmonary artery and thence recirculated through the lungs.

A PDA may close spontaneously (on its own). If not, it needs to be prompted pharmacologically to close and, if that does not work, it must ligated (tied off) surgically.

PDA is a particularly common problem in premature infants with the respiratory distress syndrome. The left-to-right shunt through the ductus increases their risk of serious complications including brain hemorrhage. IV indomethacin (Indocin) was the conventional therapy to promote closure of PDA in premies but indomethacin affects blood flow to organs such as the kidney and so may lead to complications such as renal failure. Ibuprofen (the active ingredient in Advil, Motrin, Medipren and Nuprin) has been found to work as well as indomethacin in treating PDA in preterm infants with the respiratory distress syndrome and is less likely to impair their kidney function.

The above was taken from this link.. http://www.rxlist.com/cgi/generic/piroxicam_wcp.htm please pass it on to your friend and tell her we said good luck.. I hope this information is what you needed.. if you need anything else, please let us know.. take good care.. Duck
Moderator of Arthritis Forum
Confirmed Diagnosis of - Psoriatic Arthritis/Spondylitis/Graves Disease/GERD/Scoliosis/Hiatal Hernia/Graves Disease of the Eyes/Chronic UTIs/Migraines/Hypertension
Current Meds -  Enbrel/Prilosec/Synthroid/Nitrofurantoin/Midrin/HYZAAR
Past Meds - Inderal/PTU/Prednisone/Voltaren/Feldene/Mobic/Cortisone and Steroid Shots


Stef17
Veteran Member


Date Joined Feb 2003
Total Posts : 1811
   Posted 4/8/2008 7:29 PM (GMT -7)   
Good info to have! Thank you SO SO SO much for doing the look-up on that! I sincerely appreciate it. I don't know that I'm such a good friend - it's just that I've had 2 kids while taking all of my medicine and I know you have to do your research first, so since she's never had any kids I don't think she knows where to start. I just wanted to help a little. YOU helped me help her, so THANK YOU TONS!

Ducky
Veteran Member


Date Joined Mar 2005
Total Posts : 3199
   Posted 4/9/2008 12:35 PM (GMT -7)   
Glad I could be of service! You are a good friend.. you're helping her get informed on stuff that she doesn't realize she needs to know yet.. :) If you need anything else, just give us a yell!
Moderator of Arthritis Forum
Confirmed Diagnosis of - Psoriatic Arthritis/Spondylitis/Graves Disease/GERD/Scoliosis/Hiatal Hernia/Graves Disease of the Eyes/Chronic UTIs/Migraines/Hypertension
Current Meds -  Enbrel/Prilosec/Synthroid/Nitrofurantoin/Midrin/HYZAAR/Methotrexate
Past Meds - Inderal/PTU/Prednisone/Voltaren/Feldene/Mobic/Cortisone and Steroid Shots/HCTZ

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