I have been using sulfasalazine for about 1 year. I have UC and at first I was taking about 4 pills a day but now I only take 2, otherwise I get constipated. I can not be without it. Before I started taking it I was having all kinds of problems with diareha. But I also have arthritis. Had a knee replacement many years ago and have it all over my body. I am not taking any prescription now for my arthritis. If I am in pain I will use Aleeve and if my joint swells I use my ice pack to freeze it then the pain subsides. Right now my lower back is giving me problems so I will take an aleeve before I go to my doctor's appointment. I also have Congestive Heart Failure and had a couple of stents put in a couple of years ago. The sulfer doesn't seem to affect me.
I say give it a try if you are not allergic to it. A lot of people are allergic. My sister-in law has been using it for over 10 years for diverltitis (not sure of the spelling) and she swears by it.