antibiotics for RA

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New Member

Date Joined Sep 2008
Total Posts : 16
   Posted 5/4/2009 10:19 PM (GMT -6)   
Hi all,  I have RA and am on Arava and not having enough pain relief.  At my urging my rheumy put me on minocycline 10mg twice a day and after 3 weeks had a complete remission BUT I have GERD as well and found the minocycline was giving me increased gerd side effects and severe indigestion-wonder if anyone has had success long term by self injecting some of the antibiotics thus bypassing the gut?  Any input would be appreciated as I have had to stop the minocycline and my pain is coming back.  Thanks, RETRN

New Member

Date Joined May 2009
Total Posts : 1
   Posted 5/9/2009 2:57 PM (GMT -6)   
Hey Ret -

You did not have a complete remission on antibiotics, IMHO, you had a rather dramtic lessening of symptoms. If you're on Avara, I'm guessing you haven't been on too many of the biologics. If you have, it usually takes a LOT more than 3 weeks to return to health.

Stomach upset is quite common starting Minocin/minocycline. Usually you can do a couple of things. Lower your dose and get used to it, usually a couple of months. It sounds like you're doing what's known as the Harvard Protocol - 100 mg pill 2 X a day, 7 days a week. The Brown Protocol is 200 mgs MWF. A lot easier on the stomach and less herxes (Jarische Herxheimer) reactions.

Think about using aloe vera gel to help heal the stomach. I used that to wean my PPI (nasty drug) - took months to get off that thing - talk about acid rebound effect. Just make sure you don't take it with the med. Always 2 hours around the med (no food).

And NEVER EVER forget your probiotics. Seriously, when AP fails, it's almost ALWAYS because of the probiotics.

You might consider hanging out on - a site dedicated to using low level antibiotics to heal from RA, Lupus, AS, Crohn's etc. If's its autoimmune, the abx will usually help it.

If you have any questions - ask away.

APer (Antibiotic Protocol user) - almost 3 years now.

Post Edited (Pip!) : 5/9/2009 3:00:52 PM (GMT-6)

Veteran Member

Date Joined Feb 2007
Total Posts : 553
   Posted 5/15/2009 7:58 PM (GMT -6)   
Thats interesting. I'm on abx for a nasty bladder infection and never thought that it could be a way to treat RA. It's just a short term dosage to knock the infection out- but I am going to look further into this.
Thanks for the new lead.
Current medications:
Bipolar treatment-Lamictal, 200mg, Mood stabelizer, daily(main side effect: brain fog) Bipolar treatment-Cymbalta, 40mg, Antidepressant, daily(main side effect: GI upset, decreased clotting, insominia) Anemia, Fatigue treatment- Iron supplement, 65mg, daily(main side effect: constipation) Insominia treatment- Ambien, 10mg, daily(main side effect: amnesia eppisodes between taking pill and falling asleep) Mania treatment- Alprazolam, .25mg, Very rarely(main side effect: fatigue, slowing of thoughts, depression of CNS, can't take ambien or vicodin when on it) RA treatment- Plaquenil, 400mg, daily(main side effect: GI upset, decreased clotting) RA treatment- Methotrexate, 25mg, 1X weekly(main side effects: hair loss, stomach upset, mouth sores, sore muscles, fatigue, brain fog, compromised immune system, decreased Folic Acid absorption) GI upset treatment- Leucovorin Calcium, 10mg 1x weekly(main side effects: ?) Folic Acid defintioncy- Folic Acid, 1mg, daily(main side effects: ?) RA treatment- Prednisone, 8mg(and decreasing...)daily(main side effects: increased manic eppisodes, constipation, brain fog, bone density degeneration, compromised immune system) Multi-mineral Supplement (main side effects: constipation, GI upset) Constipation treatment- Docusate Sodium, 200mg, daily(main side effects:?) pain control- Motrin, 800mg, PRN Q6hours daily(main side effects: GI upset, decreased clotting) Pain Control- Vicodin, 5-500mg, PRN Q12hours regularly (main side effects: brain fog, fatigue)

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