I wanted to let people know that Imuran is working for my RA. I have been taking it for about 6 weeks. I am certainly not pain free, but, I have picked up cases of bottled water, gallons of milk and worked in my yard, etc. and haven't paid the big, up all night in severe pain price. I am extremely encouraged. I cannot take sooooo many of the anti-inflamatory drug due to alergies that is wonderful to have positive results. I had minor stomach upset for the first week or so but then nothing. I am thrilled. Might get a little bit of my life back and maybe even take off a couple of pounds that I have gained due to physical limitations. I hope this info can help someone else.