I'm so sorry to hear about your wife and all the problems she's having, must be a very difficult time for you both?
I was on Humira for over a year, but suffered none of those side effects, sorry.
I was tired, didn't sleep too well etc but really put that donw to having AS and being on Mxth at the same time, which does bugger up your system sometimes, but does such good work at the same time.
I'm sorry I'm not really of any help to you, but wanted you to know that your not alone and someone is listening. Keep posting as so many people with so much advice and information for you - then you can make up your own mind.
I hope this week brings your wife some relief. Oh by the way it took a while for the Humira to kick in.
AS - High Blood Pressure - Irregular Heartbeats - High Cholesterol - Insulin Resistants Disease
Meds: Remicade, Methotrexat, Micardis, Verapamil, Lipitor, Metformin