Maybe you can ask your doctor about getting on methotrexate. I found it hard to tolerate but many people use it. I wonder if your doctor (and you) have considered remicade. There is some leeway with the dose which is good. Just a thought, if Orencia doesn't work out.
Diagnosed with ulcerative colitis in 2005 and rheumatoid arthritis in 1998. On Remicade since 2005 for both diseases. For UC tried sulfasalazine, Lialda, colazal and others which made me sick. Use peppermint oil capsules and Bentyl which help during a flare and with IBS symptoms, and turmeric, krill oil, CoQ10 and Methyl B12.