the Imuran @ 25mg caused no nausea or vomiting at all for me. i took it with or without food everyday... didn't make a difference.
@ 50mg Imuran, after about 3-4 weeks at that dose, it depleted my WBCs further, caused nausea that lasted for about only 2 weeks. now it's at the point where i think it only adds a little bit of exhaustion...but that could be from other crap i take or from RA and everything else. oh and some hair loss & thinning.
(((((((((BEST OF LUCK TO YOU!!!!!!!!!!))))))))))))
Thanks for the info. I thought it would probably take 3-5 weeks before I felt any major side effects. I took sulfasalazine (last fall) for 5 weeks before it lowered my blood counts. And I know that 7.5mg is not that much. I'm sure rheumy will increase it to 10mg, but not until mid-August when I see him again. I pretty much have to monitor side effects myself 'til then.
Yalinda, welcome back! Wow--you started on 10 mg! That's high. That may be my highest, have to wait and see what happens. I just took my weekly dose about an hour ago. So far so good, but we're going on vacation to the beach tomorrow so I need to do some packing just in case I feel sick later. Of course, if I feel sick, I can always blame it on mtx, and dh will pick up the slack :)
You know what freaks me out about mtx? All of a sudden it's all over the news about people dying and what not?!? I think most of the death are due to errors in dosing, though. People don't understand the once/week dosing and may take it every day (eek). Evidently, some doctors don't understand the dosing either (pretty scary thought). My rheumy was very clear, though, that it was a once a week drug. And since I already take enbrel once a week, 'tis no big deal to mtx once a week as well. My husband just told me that another woman died from mtx--inappropriate dosing. And I was reading this article that mentioned all of the people involved in making this drug safe for patients. Don't forget the pharmacist, who can either make a dosing mistake, or catch a dosing mistake that a doctor has made. For example, my insurance only authorizes medication for a month at a time (not 3 months like some other health companies). As a result, my pharmacist gave me exactly 12 pills. If he had given me 3 months at a time, I would run a greater risk of taking more than I should. It would be easy to do. Also, too many PCPs get involved in prescribing this drug, and they really shouldn't. It should be left to the specialists.
Enough of a rant! See you guys next week!!!!!!