Yalinda--MTX and cough

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elcamino
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Date Joined Sep 2005
Total Posts : 1744
   Posted 8/7/2006 12:06 PM (GMT -7)   
Yalinda, since you're taking mtx, and at a much higher dose than me right now but not for long as my rheumy plans on increasing my dose, have you ever noticed a definite cough and chest congestion for several days after the weekly dose?  I've noticed this with me, and it seems like it's lasting for  longer time each week.  For example, I take mtx Friday nights.  Last week, the cough came and lasted through Sunday.  This week, it came again after my mtx dose and it's still with me Monday afternoon.  I'm trying not to be paranoid--it's really hard to tell if it's just allergies, or perhaps I'm getting a cold, but it disappears so I'm inclined to believe it is not a cold.  Just wondered if you had experienced this, and if it ever went away?
 
Thanks
Elcamino
Current dx: Rheumatoid Arthritis
Suspected dx: UCTD/Early Lupus
Current Meds: Enbrel, Plaquenil, Aciphex, Ultracet, Zyrtec, Allavert-D, Zantac, Tylenol PM
Past Meds: Relafen, Vioxx, Mobic, Voltaren, Sulfasalazine, Entocort, Prednisone, Humira, Reglan


yalinda
Veteran Member


Date Joined May 2006
Total Posts : 1179
   Posted 8/7/2006 4:44 PM (GMT -7)   
hi elcamino,   i personally have not experienced a cough on mtx but i did remember and again just googled mtx and cough and i did get a bunch of posts....... mtx can cause a cough and a bunchof other stuff..... i am not happy i have been increased to the higher dose as i think my risks are higher for complications.  i am however doing well on it.  just real tired on weekends but i too worry about all those side effects and the recent google search has me concerned again.  i think i am going to go back and print out a few sites to ask my doctor about the statements..... i know my PCP was not happy i was on mtx because i have the 7 nodules on my lungs and he was concerned if this was contra indicated and wanted me to go for a second opinion but the referral he gave me the doctor was not taking new patients and my pcp apt has been reschedualed 2 times so i havent talked to him since early june i think, but i am suppose to c him on friday.  i would definetly chart your cough symptoms and if frequent and persistant i would phone yur doctor, also ask the pharmacist, they r real smart on those drug things but my google search did come up cough as a problem.  if you want me to copy and paste the site i will just letme know.  good luck and keep me posted  i worry about everyone out there in tv land hehehehe ~*yalinda smurf

deb in indiana
Regular Member


Date Joined Aug 2005
Total Posts : 387
   Posted 8/8/2006 11:59 AM (GMT -7)   
I have been on this since end of May iamon 6 a week at 2.5mg i started the cough thing also at night the worst the rumy said at this low dose  it wouldn,t cause the cough but i had a allergy appointment and my oxygen level went down to 70 and i asked him about this med and he also said that at a low dose it wasn't causing the cough he gave me a steriod shot antibotics and a new inhaler  i finally had to use my breathing machine to get relieve i slept better last night but i still woke up coughing 3 times but my pain has inproved a lot i haven't felt this good in 15 years and iam doing things now but he wants to put me on remicade next month for the arthritis and iam going to a new pain doctor and he has me on zanaflex and viciden so if i don't quit the cough and conjectioni am going to have to go off of it so take care and i hope i helped you some DEb

elcamino
Veteran Member


Date Joined Sep 2005
Total Posts : 1744
   Posted 8/8/2006 2:52 PM (GMT -7)   
Thanks Yalinda and Deb. I will mention it to my rheumy when I see him next. Deb, I'm surprised your doctors said that mtx couldn't cause a cough at the low doses we use. Everything I've read so far states that the mtx side effects are NOT dose dependent. In other words, you can have serious side effects with only 7.5 mg/week (the lowest dose given, I believe).

Honestly, I'm hoping that it's not the mtx because I'm now convinced that adding the mtx to the enbrel has made all the difference in the world. I don't want to stop taking it; I've had such a great response to it so far.

Elcamino
Current dx: Rheumatoid Arthritis
Suspected dx: UCTD/Early Lupus
Current Meds: Enbrel, Plaquenil, Aciphex, Ultracet, Zyrtec, Allavert-D, Zantac, Tylenol PM
Past Meds: Relafen, Vioxx, Mobic, Voltaren, Sulfasalazine, Entocort, Prednisone, Humira, Reglan


yalinda
Veteran Member


Date Joined May 2006
Total Posts : 1179
   Posted 8/8/2006 3:21 PM (GMT -7)   

hi elcamino, deb, and anyone else...... ok just came home from the rhuemmy visit..... he up'd my mtx! i now will take 8 pills a week devil and i had a rather long discussion with all my concerns and i will post here his answers but this might be a long one?

ok i asked about the cough thing, and his response was how often and when do i cough, i then said never hehehehehe  he looked at me a bit crazy and then i told i was asking for a friend, his response was ~ any question about effects or changes should be brought to the doctors attention.  he said if the cough is caused by the mtx the doctor would hear sounds in the lungs and that is why he listens to my lungs each week.  he didnt go into real detail with that other then to say my friend should let their doctor know.

i then asked about my conncerns being on mtx devil   the evil drug devil   he laughed and asked me what exactly i was concerned about.  i said for starters my liver, his reply was that mtx was safer than most other drugs like motrin i always get that group name mixed up is it nisads ( i know i am wrong with this abrv.  but that group of drugs) he feels is worse long term on my liver then mtx.

i also asked about my increase risk to lymphoma on mtx and his response was that he thinks mtx will decrease my risk and it is RA that increases my risk.  i noted internet studies and he stated  controlling the disease may actually decrease my risk which is elevated for lymphoma but taking the mtx, and of course people with RA on mtx may still get it but so will people with RA not on mtx.  he noted studies are just that and often have variables not consistants. 

he stated he thinks mtx is successful and safer than uncontrolled RA and it would be his drug of choice. he understood my concerns and told me if i wanted off he would try other treatments but i have agreed to continue on as i am feeling fairly well. 

elcamino, i did mention my fatigue and he told me to take it at bedtime on friday and if still tired on sat. to split it half friday night half sat. night.  soi felt like a jerk not thinking to take it at night verses day redface

i cant answer for anyone else here but i am on this journey now tkg a total 20 mg weekly of mtx in hopes on decreasing the prednisone to zero someday.... good luck to everyone i have to trust my doctor for now, hope it doesnt come back to bite me in the butt hehehe tongue ~*yalinda


elcamino
Veteran Member


Date Joined Sep 2005
Total Posts : 1744
   Posted 8/8/2006 4:20 PM (GMT -7)   
Hey Yalinda, Glad your appt. went so well. Gee, thanks for asking your doctor my question :) I will bring it to my rheumy's attention if it's still an issue when I see him in a couple of weeks. I told my husband if my cough gets worse after my next dose, I'll call my rheumy's office on Monday (I take the mtx on Friday evening). Rheumy told me to take it in the evening before I go to bed. I must say, it does make me a little light-headed a couple of hours after I take it, so I'm glad I'm taking it at night--after my girls are in bed.

I'm pretty tired this week, so far and I've been going to bed much earlier than usual. If I have a little virus, though, that's probably what's making me so darn tired.

Good night!

Elcamino
Current dx: Rheumatoid Arthritis
Suspected dx: UCTD/Early Lupus
Current Meds: Enbrel, Plaquenil, Aciphex, Ultracet, Zyrtec, Allavert-D, Zantac, Tylenol PM
Past Meds: Relafen, Vioxx, Mobic, Voltaren, Sulfasalazine, Entocort, Prednisone, Humira, Reglan

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