Hi Roza, from what I understand mtx interrupts the folic acid pathways. That's why when we're prescribed mtx, we're usually told to also take folic acid. Taking the folic acid supplements will decrease the risk of side effects from the mtx. If you're still taking mtx, I would recommend you ask your doctor about continuing the folic acid. I wouldn't want to take mtx without the folic acid. I don't believe folic acid has anything to do with pain killers.
Current dx: Rheumatoid Arthritis
Suspected dx: UCTD/Early Lupus
Current Meds: Enbrel, Plaquenil, Aciphex, Ultracet, Zyrtec, Allavert-D, Zantac, Tylenol PM
Past Meds: Relafen, Vioxx, Mobic, Voltaren, Sulfasalazine, Entocort, Prednisone, Humira, Reglan