Enbrel v. Remicade

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New Member

Date Joined Jul 2007
Total Posts : 13
   Posted 7/24/2007 5:27 AM (GMT -6)   
I'm wondering what are the advantages/disadvantages of both.  I don't know if I would like giving myself injections, but does Enbrel work better than the Remicade? 
My rheumy is doing my medication in stages, so if the remicade doesn't work will I move up to enbrel or humira?

Veteran Member

Date Joined Sep 2005
Total Posts : 1744
   Posted 7/24/2007 10:37 AM (GMT -6)   


I don't know that enbrel or humira would be a step up to remicade.  Many others might consider remicade a step up from enbrel.  My rheumy considers all of them rather equal, and very individual.  what works for one person may not work for another, tra-la-la. 

I was on enbrel injections for close to a year, and I can tell you I would much rather give myself an injection (it's not that bad) than have to take a whole day getting an infusion.  Plus, I believe with enbrel you have the sure click option, which makes the injection that much easier.  I've never used sure click, but I believe others on this board have.

The advantage of remicade, though, is that you only have it done every 6-8 weeks (depending on the patient).  Keep in mind that for a lot of people, myself included, it took a long time for the enbrel to kick in (don't know about remicade).  It me almost 7 months before I felt any significant effects from the enbrel; however, it can take as little time as 2 weeks.

Best of luck with the remicade.


Current dx: Rheumatoid Arthritis
Suspected dx: UCTD/Early Lupus
Current Meds: Enbrel, Plaquenil, Aciphex, Ultracet, Zyrtec, Allavert-D, Zantac, Tylenol PM
Past Meds: Relafen, Vioxx, Mobic, Voltaren, Sulfasalazine, Entocort, Prednisone, Humira, Reglan

Veteran Member

Date Joined Mar 2005
Total Posts : 3199
   Posted 7/26/2007 5:30 PM (GMT -6)   
Hey there bamabelle.. El is right.. usually Remicade is given AFTER Enbrel and Humira.. Have you had your 1st Remicade infusion yet?
Moderator of Arthritis Forum
Confirmed Diagnosis of - Psoriatic Arthritis/Spondylitis/Graves Disease/GERD/Scoliosis/Hiatal Hernia/Graves Disease of the Eyes/Chronic UTIs
Current Meds -  Enbrel/Prevacid/Synthroid/Nitrofurantoin
Past Meds - Inderal/PTU/Prednisone/Voltaren/Feldene/Mobic/Cortisone and Steroid Shots
Additional Supplements - Multi-Vitamin/Bromelian/Acidophilus/Green Tea

New Member

Date Joined Jul 2007
Total Posts : 13
   Posted 7/28/2007 7:38 PM (GMT -6)   
No.  The insurance company is in the process of "approving" the infusion for Remicade.  I'm excited to finally start on something that may help.  I was just curious if there was an advantage to the remicade over the enbrel/humira.  I'm not thirlled about the prospect of the infusion therapy, but anything to get back to normal!

Veteran Member

Date Joined May 2006
Total Posts : 1179
   Posted 7/29/2007 2:51 PM (GMT -6)   
hi my rhuemmy gave me a choice between the three telling me that:
enbrel- weekly injection and does not stay in system long approx 3-4 days. so if i got sick i could recover quicker as it is not a long tern comprimise to my system
humira is every 2 weeks a shot and it is in your system up to 14 days so if i got sick i would have a longer recovery period if i got sick early in the shot phase
remicaid is long term every 6-8 weeks for i was told a half day infussion off from work weekdays which i could not afford to do.
based on this info i chose enbrel because i am around a lot of people all the time and often ill ones so i felt for me it was the better choice if it works and the rhuemmy agreed.

that is how it was explained to me, or how i understood it lol
good luck! yally

Veteran Member

Date Joined Dec 2005
Total Posts : 1782
   Posted 7/30/2007 12:11 AM (GMT -6)   
I started on Enbrel, it worked quite well until I had a severe infection in my gums (under a tooth). When we got the infection/tooth issue solved, I went back on it and it wasn't as effective. My doctor then added MTX to the mix, which helped immensely. Last year I was diagnosed with Crohns and I was switched to Remicade (since it works for all of my issues AS, RA & CD). It has been my magic drug! I'm still on the MTX, but personally I feel it's working way better than the Enbrel pre-infection. Self injections are really nothing to worry about - you get used to them.

I was on the 2x week Enbrel shots, now I'm on the 6 week Remicade schedule - the infusions take about 2 hours at the infusion center. Seems to be working just right along with my weekly MTX shots. If one doesn't work well for you, you do have the option of the others. I hear there is another biologic coming out as well, so that will be one more "just in case." Keep in mind, most people do not experience relief right away. For me, it took 3 months with Enbrel and about 1-1/2 months with the Remicade. Of course, you could experience relief right away - some people do. Whatever you decide, I wish you the best.

"My "Trifecta" - CD, AS & RA...

Some days you're the bug, some days you're the windshield

Co-Moderator Crohn's Forum

Remicade every 6 weeks, Methotrexate weekly, Folic Acid daily

Regular Member

Date Joined Sep 2007
Total Posts : 26
   Posted 9/25/2007 12:30 PM (GMT -6)   
Hi bamabelle214,

DX RA/Osteo about 5 years now. On methotrexate, plaquenil, prednisone, etc. Considering adding either enbrel or humera. Have a close friend on Remicade. She has been on it for 2 or 3 years now. Her RA is very agressive as mine. She tried enbrel befofre the remicade but she claims the enbrel did not seem to work for her. At the time, she was still working long hourse. I took a disability retirement and seemed to be able to manage with just the oral meds as opposed to going to remicade, etc.

However, now, my flare ups are coming more and more often and difficult to manage the pain at times.

I am thinking I would prefer to try the enbrel or humera before the remicade because of the convenience of being able to give myself the injections and not having to go to hospital for infusions. I't rather wait on that. Just depends, I guess, on your lifestyle and present situation. You and your doctor can best determine.

Just thought I would let you know my experiences. Hope it helps a little.

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