Hey Duck. Thanks for responding. Yeah, I suppose I could go back on enbrel, but I don't want to. Mtx is doing just fine by itself (much better than enbrel did by itself, and it costs a mere fraction of the price of enbrel. Both of my parents took mtx for 15+ years with no problems, so my rheumy will probably want to leave me on it anyway. I will NOT take enbrel and mtx together again--I caught too many weird things.