Will I get a moon face from taking 3 1000mg doses of Solu-medrol?

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New Member

Date Joined Aug 2007
Total Posts : 2
   Posted 8/7/2007 1:28 PM (GMT -6)   
Will I get a moon face from taking 3 1000mg doses of Solu-medrol?

I don't have Arthritis , but I believe people with it take Solu-medrol. I will be taking a pulse of 3 1000mg doses of Solu-medrol then stopping the medicine all together( I will not be doing a taper down of any medications nor will i be having the pulse at all after this). I was wondering if I would get a moon face from taking the medicine over this short period, if so how long will it last? I have taken prednisone before and hated it, just as most others. I am going to be taking this to try and minimize the side effects.

Thank you.

Veteran Member

Date Joined Mar 2005
Total Posts : 3148
   Posted 8/9/2007 8:37 AM (GMT -6)   
dear rn,
hi & welcome! :-)
may i just ask...you stated that you're taking it to "minimize the side-effects."?
will you be receiving chemotherapy? and the SoluMedrol, they're giving to reduce nausea?
to start, everyone is going to react quite differently to steroids.  much has to do with your body's mechanics to begin with.  some people don't hold water or swell easily while others may have edema right away.
this sounds to me as though you might be getting this through IV?  in the hospital?  or will you be taking it orally?
the way in which Solu-Medrol acts differently from say Prednisone, is that Solu-Medrol is a teeny bit more intermediated-acting (a little more short lived)
i know what you are talking about with "pulse" therapy = a high dose abd that goes by (usually)30mg/kg of body weight  IV every 4 to 6 hours.
"moonface"  typically results from a long term steroid use but you may get puffy just from the amount of fluids alone.
best thing to do is express your concern w/ your doc & should you feel any discomfort or tightness in your face & skin...let em' know right away.  they may have some quick fixes to help you feel better & help push fluids away.
the very best to you & good luck!
Arthritis Forum Moderator & Co-Pilot
Active Severe Rheumatory Arthritis. AS. Crohns Disease. A.Chiari Malformation & right brain venous anomoly. Partial Complex Seizures (under control!). MVP & Tricuspid Valve Prolapse. Rheumatic heart & lung. Kidney Stones (oh joy). Previous Lymes Disease for 10 years.
Meds: Remicade infusions 600mg Q3weeks; Intra-articular knee injections; 6MP 50mgQD plus 75mg weekly; Mesalamine 4GramsQD; Prednisone 20mgQD; Entocort 9mgQD; Meclizine; Augmentin; Tigan; Reglan; LidoDerm; Diazepam; Rozerem; Diclofenac; Celebrex; Dilaudid 4mg; Duragesic 25mcg/hour. 

Veteran Member

Date Joined Nov 2006
Total Posts : 1331
   Posted 8/9/2007 11:09 AM (GMT -6)   
Erin gave good advice to you, and I have not taken the medrol in the same form that you plan too, however I have had several dose packs back to back..and I never developed a moon face, but I went from from feeling very hot and flushed to feeling icy cold and my face was red and I developed a rash on my face (splotchy). My hands and fingers did get puffy as well as my feet somewhat. All of this went away after I stopped the Medrol packs.

Gladys Ann
New Member

Date Joined Jun 2007
Total Posts : 18
   Posted 8/20/2007 8:37 PM (GMT -6)   
I've been taking Medrol for six months now, and I did develop a moon face, but when my dosage was reduced, my face went down.  Moon face is not permanent, thank God.  I hated my moon face and I was so glad to return to my normal self.   
Let us know what  happened.
Good luck.
Gladys Ann
Diagnosed with RA and COPD
MEDS:  Humira 40mg everyother week, Medrol 4 mg. daily, Cymabalta, Ultracet and  Vicodin
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