I get severe cluster migraines that last days, which doesn't help when you are having an arthritis flare for certain! One of my docs recommended Botox for some relief; I know some injectables are contraindicated for patients on immunosuppresants and such, but I am getting mixed opinions from my doctors. Is anyone on similar drug combo and got the green light for Botox/know it is safe? My rheumy doesn't know; my other doc says ok; the botox doc is hesitant. I would love to get some relief, my headaches last from 2-3 days and sometimes I get them two or three times a month, part of my autoimmune disorders according to my rheumy. Thanks so much!