New Study - what do you think?

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

What?
New Member


Date Joined May 2008
Total Posts : 11
   Posted 7/15/2008 11:28 AM (GMT -7)   

N-Acetyl Cysteine May Support Emotional Health
Breaking News

 

By VRP Staff
A new study has found that N-acetyl cysteine (NAC) may improve depressive symptoms in bipolar patients.
One of the challenges people with bipolar disorder face is that they are subject to depression that is often treatment resistant. Furthermore, depletion of glutathione, an important antioxidant, is thought to complicate the symptoms of both depression and bipolar disorder. Consequently, scientists decided to investigate whether NAC, which is a precursor to glutathione, could improve the depressive component of bipolar disorder.
In the randomized, double-blind, placebo-controlled study, researchers studied 75 subjects with bipolar disorder that was in the maintenance phase. Over 24 weeks, they gave the subjects 1 gram twice per day of NAC along with the subjects' usual medication. The study authors then judged the efficacy of NAC by noting how the subjects measured up on the Montgomery Asberg Depression Rating Scale (MADRS). The researchers also looked at how the subjects did on the Bipolar Depression Rating Scale and 11 other ratings of clinical status, quality of life, and functioning.
According to the results, NAC caused a significant improvement on the MADRS depression rating scale and on a number of other measurements of depression. Improvements were lost when the subjects stopped taking NAC.
The researchers concluded, "NAC appears a safe and effective augmentation strategy for depressive symptoms in bipolar disorder."
Reference:
Berk M, Copolov DL, Dean O, Lu K, Jeavons S, Schapkaitz I, Anderson-Hunt M, Bush AI. N-Acetyl Cysteine for Depressive Symptoms in Bipolar Disorder-A Double-Blind Randomized Placebo-Controlled Trial. Biol Psychiatry. 2008 Jun 4.


serafena
Veteran Member


Date Joined May 2007
Total Posts : 3715
   Posted 7/15/2008 2:44 PM (GMT -7)   
This is a nutritional supplement. Remember that supplements aren't regulated by law, but if you do a little research, it seems this one has some small trials to back it up.

serafena
Serafena
Co-Moderator, Bipolar Forum
Bipolar II


M73
Regular Member


Date Joined Jul 2008
Total Posts : 88
   Posted 7/15/2008 4:09 PM (GMT -7)   
So, maybe one of my more naive questions, but where does one obtain this umm, lemme check, n-acetyl cysteine?

I'm taking fish oil caplets at the moment.

CapninHapnin
Regular Member


Date Joined Sep 2006
Total Posts : 285
   Posted 7/15/2008 8:05 PM (GMT -7)   
Isn't this an infraction of our rules?
I want "I wish I had one more day to spend at the office" on my tombstone.

I used to be crazy, but now I have enough money to be called eccentric.


Becca30
New Member


Date Joined Jul 2008
Total Posts : 4
   Posted 7/15/2008 9:55 PM (GMT -7)   
This sounds worth trying. Do you think you can find it at a health food store?
New Topic Post Reply Printable Version
Forum Information
Currently it is Saturday, December 10, 2016 7:28 PM (GMT -7)
There are a total of 2,736,163 posts in 301,356 threads.
View Active Threads


Who's Online
This forum has 151449 registered members. Please welcome our newest member, iwanttocry.
265 Guest(s), 5 Registered Member(s) are currently online.  Details
bluelyme, Ides, tickcheckguy, Lynnwood, minnietoty


Follow HealingWell.com on Facebook  Follow HealingWell.com on Twitter  Follow HealingWell.com on Pinterest
Advertisement
Advertisement

©1996-2016 HealingWell.com LLC  All rights reserved.

Advertise | Privacy Policy & Disclaimer