I'm 29 and a mother of 3. Ages 7, 20 months and 8 months. I was diagnosed with PPD in 2001 then eventually diagnosed with severe depression. I have been on several different medications just switching from my latest Zoloft 150mg to Venlafaxine 75 mg plus Ativan 1mg. BD runs in my family as well as depression. With this medicine I'm on currently I feel as if I'm doing worse. My family has mentioned I need to get tested for BD b/c I'm constantly on edge, I'm frantic one min and then completely calm the next, I have severe mood swings, I'm more down than up, I can't sleep, I feel hopeless and exhausted, I can't concentrate on anything, I have no energy to do anything although I make myself but I feel so out of it, I feel as if I do not want my children anymore, I feel like I don't want to be married anymore. I don't know if I'm overwhelmed with it all b/c I have 2 babies and they both constantly cry and I mean constantly. I lost. I feel horrible for having these feeling and feel like I'm a terrible mom for even thinking the way I do. I want to enjoy life and my kids but I just can't seem to get out of this "hole". Suggestions are appreciated.