I don't know the specifics but I do know that quite a few meds recommend not being taken with grapefruit juice.
How does grapefruit juice affect medicines?
Grapefruit juice contains chemicals that can cause problems with enzymes that break down certain types of medicines in your intestines. When a medicine does not get broken down properly in the intestines, you can have too much medicine in your blood. The chemicals in grapefruit juice can also cause you to have not enough medicine in your blood. Having too much medicine in your blood increases your chances of having side effects.
Which medicines are affected by grapefruit juice?
Most medicines are not affected by grapefruit juice. And not all medicines for the health problems listed below are affected by grapefruit juice. But more than 50 medicines are affected by grapefruit juice
This is from WebMD:
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