Advice for Long term use of Atypical Antipshychotics

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ravdeep
Regular Member


Date Joined Sep 2016
Total Posts : 59
   Posted 1/2/2017 12:32 AM (GMT -7)   
Hello everyone, i was wondering if i could pick your brain on this matter. Any suggestions would be greatly appreciated. I'm on seroquel 100mg btw.


How often should one get tested for serum Cholesterol, Triglycrides, Thyroid function, Blood sugar while taking AAP's for long term?

Are all these adverse effects possibly dose dependant? Would staying at lowest possible dosage give me better odds of not experiencing these side effects?

Is it possible that i may not experience any of these side effects at all? like is it more person to person specific?

And lastly, can Metformin, the anti diabetic med, help decrease the metabolic side effects (weight gain, cholestrol, Triglycerides?

Tim Tam
Regular Member


Date Joined May 2016
Total Posts : 491
   Posted 1/2/2017 3:49 PM (GMT -7)   
The net says bipolar II reaches hypomania but not full blown mania, so I must have bipolar I, because without my Lithium I can reach full mania.

So you're in a better situation than I am. As noted, I take Lithium, which lifts my depression and brings down my mania. I also take Mirtazapine anti-depressant.

I took an anti-psychotic for some time years ago, and that all the psy. gave me, and it stripped all of my emotions (anger was the one he was trying to reduce) but it also stripped me of good emotions, so I was like a zombie. That was the only med I took, I wasn't really being treated for manic-depression, I was being tortured.


Anyway, what anti-psychotic are you taking? Are you doing OK on it? Do you take an anti-depressant? (Oh, I see you wrote that you are on Seroquel. I took that for awhile. Do you do OK on that?)

I think you said you had health anxiety, and I don't know much about what. But what I do usually is just take the medicine and hope it takes away my depression or my mania.

The side effects, having mania or depression is a side effect of not taking medicine. That's my main concern, my mania or my depression, and I don't worry about the 50 side effects they list on those printouts. I know they have caused me trouble sometimes, and I'll try to deal with the side effects should the occur.

I don't sit there and worry about the 50 side effects before any of them have occurred. What I do worry about is getting my mania calmed down, or getting me out of depression. I worry bad about that.

A possible side effect 6 months down the road? No. Just get me out of my emergency.

I would deal in the here and now, not worrying about slipping on a banana peal 6 months down the read, which probably is not going to even happen.

What are some things that you enjoy? What are your favorite TV shows? What are your favorite songs?

ravdeep
Regular Member


Date Joined Sep 2016
Total Posts : 59
   Posted 1/2/2017 8:41 PM (GMT -7)   
I hear what you're saying. Focus on fixing what's wrong NOW. It's good advice. I'll try to follow that from now on.

Seroquel works like a charm for me. But I can't take the required therapeutic dose Coz it wreaks havoc with my appetite. I constantly crave sugar and high carb food. So I stay at the lowest dose 50mg.

Depression and anxiety are my main concerns. I take wellbutrin. I helps some. I haven't tried any other anti depressant but I'm thinking about it. Maybe zoloft or Prozac.

I'm a big TV buff. I watch almost all drama series that releases every season. I enjoy listening to indie/ alternative genres. There nothin like a good song to get me out of my head.

UserANONYMOUS
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Date Joined May 2011
Total Posts : 4249
   Posted 1/3/2017 7:10 AM (GMT -7)   
Hi ravdeep,

Meds have different effects on everyone. Everyone is different. Therefore, not everyone will experience the same side effects.

Sometimes we have have to try different meds before we find the right combination. I am glad that you are aware of how Seroquel and the other meds affects your body.

Music is relaxing. I enjoy music as well. Music use to be my life until depression took over.

I hope you are doing well today.

UA
Moderator - Bipolar

Depression, Borderline Personality Disorder.
Chronic Pain - Cervical Kyphosis, Cervical Spondylosis, Thoracic Scoliosis.

Tim Tam
Regular Member


Date Joined May 2016
Total Posts : 491
   Posted 1/3/2017 11:34 AM (GMT -7)   
Thank you for your nice response.

I think it's good that you are reaching out for information.

1. You said. "I'm on seroquel 100mg btw." Then your 2nd post said you were on 50 mg of that. Are you doing OK with the drop in mg.?

What was your situation prior to taking medicine. You said bipolar. What was your living situation like. Were you able to function? If trouble, what kind of trouble were you having? For how long?

Do you seek attention immediately, or wait? How did you know who to go to? Did you have anybody helping you?

Do you see a psy. now?

2. You say, "How often should one get tested for serum Cholesterol, Triglycrides, Thyroid function, Blood sugar while taking AAP's for long term?" I wait for my doctor wants be to get those things tested?

3. Are all these adverse effects possibly dose dependant? Would staying at lowest possible dosage give me better odds of not experiencing these side effects?

Lower does probably help reduce side effects, but too low can perhaps bring back the illness.

4. Is possible you won't experience any side effects. It's also possible you may have some side affects but not to the degree that you'd rather really be depressed or manic than have a small side effect or two.

I'll tell you a story. I have an ailment that is neg. effected by meds. I had a recent situation where my ailment got worse, and my meds were affecting it worse, to the point I could barely function. I thought it was over.

Then I hit upon the idea of doing a couple of things: One, Years ago I found out that most people are allergic to three things: One is wheat, one is cows milk (the lactose?), and sugar made my condition worse.

I don't eat sugar anyway, because of my health condition. The cows milk, years ago I drank only goat's milk, for it had no lactose, or something like that. I went back to goats milk only. Three, I use to eat wheat-free bread, because I, like everybody else, is allergic to wheat and it hurts my condition. I went back to eating only (mostly) wheat-free bread from the health food store.

I then, are you still there? I then dropped in dosage with 2 of my 3 meds, b/p and Lithium. Whoa. Skimming the tree tops. It helped my condition temporarily.

When my cond. improved enough, I told this person, "The reason I didn't speak to you the first two times I saw you, was because it hurt to talk." With the lower of medicine, and the absence of good that I'm allergic to, by condition improved to the point where I can function. Oh, happy day. I thought it was over.

Now, I pretty much back to all of my meds, but I tell myself I can just lower the dosage for some hours if there's a situation where I might need to talk.

But if don't have such an emergency situation, I wouldn't change anything with my meds.

5. You say, "And lastly, can Metformin, the anti diabetic med, help decrease the metabolic side effects (weight gain, cholestrol, Triglycerides?"

I don't know about Meformin. I have diabetes, but I don't know about Metformin. Do you have diabetes? have you checked out the diabetes forum on this website, and ask that same question, and others, there?


You say, "
I hear what you're saying. Focus on fixing what's wrong NOW. It's good advice. I'll try to follow that from now on."

Here's some other things that have helped me. "One problem at a time, and be positive about that problem."

"The main person you have to worry about is the person you have to look at in the mirror every morning."

Also, can you get out? Volunteer work can help you to focus on, and try to help, someone else's problems rather than dwelling only on your own.

I watch TV, also. I like true life crime shows and biographies which deal with other people's lives, which is probably why I'm interested in yours.

Post Edited (Tim Tam) : 1/4/2017 10:30:59 AM (GMT-7)


ravdeep
Regular Member


Date Joined Sep 2016
Total Posts : 59
   Posted 1/4/2017 1:34 AM (GMT -7)   
Before taking meds, when things started to get worse, i saw my life slip out of my hands right in front me and i felt helpless, like there was nothing i could do stop it. Every day i was loosing a little of myself. I was scared, terrified all the time. Didn't knew what was happening to me, or how i could fix it.

Anxiety is a brutal and unreasonably cruel sickness. Something bad will happen, that's what ran through my head day and night. It's like a switch has been flipped and I saw the world from a different place. A place of fear. Where I used to see food, now I saw unhealthy oils that could kill me. Back when I lived in Canada for a few years I practically lived on pizza, burgers and fries. Back then food was just food. Life was simple. But now I saw monsters everywhere. Couldn't go near fried food. The party was over.

Turned to Internet to look for things that could kill me. So that I could protect myself by cutting them out of my life. Worst thing I could've done. It was like adding gasoline to fire. There's research on almost everything we eat, eggs, milk, pesticides and chemicals in fruits, red meat, linking them to cancer. I felt like I was being backed into a corner at the edge of a cliff.

It wasn't just food. I couldn't even stay in the sun for long, thought I'd get skin cancer. One day I just couldn't take it anymore, I left school in the middle and drove home and just hid in my room. I knew I needed help, it was time to seek a doctor. I found one and Told him that everywhere I see, I see cancers and other life terminating illnesses. The whole story.

Never got any kind of support from family or friends. Pshcyh disorders are very very rare in India. So people are ignorant. All I got for support was, "don't think about all that negative stuff. Try to stay happy."
I didn't give up though. I fought back. Made good choices. Worked out 2 hours everyday 5 days a week at the gym. My doc didn't knew I had bipolar back then, I was put on serouel as an adjunct therapy to antidepressants that I was on ( pristiq and wellbutrin). I noticed a difference in my anxiety after starting serouel. I researched and found out that it definitely benefits people with anxiety. So I doubled the dose to 50 mg. It fixed me enough to keep me functioning. Although I was never free of anxiety. One or other fear always stayed in my conscious. Like a fellow traveler. But I wasn't overwhelmed by multitude of fears anymore. So I focused on regular life, my dreams and goals. I studied hard, I even went on stage a number of times for public speaking and I nailed all my presentations. Besides the fact that I was always terrified on the inside (not by the stage fright, that I actually find exhilarating, but by my irrational fears, cancers and such). I managed to secure a job, a decent job with a good future prospects. (which is extremely hard these days out here, thousands competing for the same job, all replaceable.) it was hard, I still remember answering the questions of the interviewer with noises in my head screaming cancer! Cancer! Cancer!. It wasn't easy but I did it. I was the first in my class to get placed 6 months before I graduated. That was kind of a big thing.

You see, Part of the reason I didn't get well fast enough was coz of the negative aura of my family. Father's a proud alcoholic and a bully and a tyrant. A mom who never knocked on my door to ask how I was doing with my condition. They all couldn't care less. Left me to fend for myself.

So I was excited to get away from them. My job was in a city far from home. A new life seemed looming on the horizon, almost within reach. I saw myself hanging out with friends after work. Go dancing in the clubs and flushing out all the worries with stream of sweat draining out of my body.

But that didn't work out. My mom and dad had other plans. I kinda needed their financial support for the first year of my job. They don't pay a lot in the beginning. And my parents refused support me. Even though they're well off. And could very easily have supported me too. They wanted me to get a job near my home. Wanted to keep me near where they could control my life. No local company came to my campus. They all offered jobs far far from home.

Then the last date for joining ( the company that hired me) came. I begged my folks to let me go. Told them if stay at home with my thoughts and fears i'll lose my mind ( what left of it anyway). But no mercy. They didn't budge. That night I got out all my benzo's and washed them down my throat with alcohol. The idea of staying at home, trapped with the heartless animals and loosing the best chance of having any kind of life, a chance that I had earned with years of hardwork, was enough to convince me that it's not worth living anymore. I don't remember what happened after I passed out. I woke up after 3 days in a hospital bed. I've been stuck, no trapped is a better word, here in a room at my home for 8 months. During this time not once have anyone from my family came to check on me. Or came at all for that matter. All these months I've been trying to figure out the right meds. It took me till now to figure out something that works. I went back on my old meds Seroquel pristiq and wellbutrin. And it works. I'm finally getting better. I've asked my friend to get me a job. Hopefully i'd start working soon.

thats my story.

And about the drop in dosage of seroquel, that was just temporary. I needed to wake up early a couple mornings. Thought cutting the dosage might help with that. I went and saw my doc today and got the 100mg in XR. Hopefully this well help with sedation.

And last, the reason i am so concerned about what tests to take and when to take is coz psychiatrists out here aren't so proactive. They wait until crap hits the fan to do something about it. So I try to stay diligent myself by gathering as much information i can.

Post Edited (ravdeep) : 1/4/2017 7:22:20 AM (GMT-7)


Tim Tam
Regular Member


Date Joined May 2016
Total Posts : 491
   Posted 1/5/2017 11:10 AM (GMT -7)   
Thank you for telling your story. I was wondering how long you had been having difficulty and what sort of difficulty that was.

If you’re from India, you write English very well. Did that take awhile?

You said, “Before taking meds, when things started to get worse, i saw my life slip out of my hands right in front me and i felt helpless” (from anxiety you said).

Then food that could hurt your became a problem, then potential skin problems then came home for college and hid in your room.

You said, “Never got any kind of support from family or friends. Pshcyh disorders are very very rare in India. So people are ignorant. All I got for support was, "don't think about all that negative stuff. Try to stay happy."

You said, “I didn't give up though. I fought back. Made good choices. Worked out 2 hours everyday 5 days a week at the gym.

My doc didn't knew I had bipolar back then, I was put on serouel as an adjunct therapy to antidepressants that I was on ( pristiq and wellbutrin). I noticed a difference in my anxiety after starting serouel. I researched and found out that it definitely benefits people with anxiety. So I doubled the dose to 50 mg. It fixed me enough to keep me functioning. Although I was never free of anxiety. One or other fear always stayed in my conscious. Like a fellow traveler. But I wasn't overwhelmed by multitude of fears anymore. So I focused on regular life, my dreams and goals. I studied hard,”

Ok, no were’re down to studied hard.

You said, “I managed to secure a job, a decent job with a good future prospects. (which is extremely hard these days out here, thousands competing for the same job, all replaceable.) It wasn't easy but I did it. I was the first in my class to get placed 6 months before I graduated. That was kind of a big thing.”

Now we’ve got a good job.

You said, “You see, Part of the reason I didn't get well fast enough was coz of the negative aura of my family. Father's a proud alcoholic and a bully and a tyrant. A mom who never knocked on my door to ask how I was doing with my condition. They all couldn't care less. Left me to fend for myself. “

OK, negative growing up family. Sound like mine. (But they managed to instill it in me, sounds like you escaped.)

You said, “So I was excited to get away from them. My job was in a city far from home. A new life seemed looming on the horizon, almost within reach. I saw myself hanging out with friends after work. Go dancing in the clubs and flushing out all the worries with stream of sweat draining out of my body.”

This is getting so good you could almost make it into a movie.

Then you say, “But that didn't work out. My mom and dad had other plans. I kinda needed their financial support for the first year of my job. They don't pay a lot in the beginning. And my parents refused support me. Even though they're well off. And could very easily have supported me too.

And “They wanted me to get a job near my home. Wanted to keep me near where they could control my life. No local company came to my campus. They all offered jobs far far from home.”

Then you say: “Then the last date for joining ( the company that hired me) came. I begged my folks to let me go. Told them if stay at home with my thoughts and fears i'll lose my mind ( what left of it anyway). But no mercy. They didn't budge.”

Then you passed out.

Then, “I woke up after 3 days in a hospital bed. I've been stuck, no trapped is a better word, here in a room at my home for 8 months. During this time not once have anyone from my family came to check on me. Or came at all for that matter.

You say, “All these months I've been trying to figure out the right meds. It took me till now to figure out something that works. I went back on my old meds Seroquel pristiq and wellbutrin. And it works. I'm finally getting better. I've asked my friend to get me a job. Hopefully i'd start working soon.

“thats my story.”

You say: “And last, the reason i am so concerned about what tests to take and when to take is coz psychiatrists out here aren't so proactive. They wait until crap hits the fan to do something about it. So I try to stay diligent myself by gathering as much information i can.”

As for tests, can you look that up on the net? I could try, but if you find anything on the next about when you should take such tests, that might be help.

But you say, “I went back on my old meds Seroquel pristiq and wellbutrin.”

I’m not sure those 3 require tests. I take Lithium, for bipolar, and my doctor wants me to take a blood test every 3-6 months, I can’t remember.

I think I’ve realized that Lithium (salt) can cause kidney damage, and my psychiatrist is wanting to check that to see now much Lithium I have in my system, and maybe to check on kidney function to make sure my kidneys are working OK.

Lithium is a large amount of salt, I’m believing, and I guess too much salt in your system can hurt your kidneys.

(The anti-depressants I've taken for years [now Mirtazapine] have never required a blood test.)

I think you’ve been right on a lot of these things, but I think your doctor is right on this one. You don’t need a test. That’s just my guess.

As to your overall situation, it is heartbreak. Interesting story.

Your parents remind me of my growing up home. Rough. Your parents remind me of the world: rough. Yeah, like my neighborhood: rough.

Maybe if you can get this job, you can make some money to get back to your old job that you liked do much. Really an interesting story, about what’s going on on the other side of the world.

You said psych med conditions are bad in India, this guy in another country wrote in and said those psy conditions there had no emphasis put on them. And they gave his wife 4 meds for manic-depression, and all she did was stare at the wall.

So you sound like you got it better.

Where did your anxiety come from parents, or they can skip a gen., grandparents?

Over all, are you depending on this job to get you back into the nightclub scene, or what?

Or you going to move out away from your parents? (I hope, I hope, I hope.)

Any siblings who went through the same thing?

Again, I appreciate you telling your story. You really went and down the scale. Whew!

ravdeep
Regular Member


Date Joined Sep 2016
Total Posts : 59
   Posted 1/6/2017 12:41 AM (GMT -7)   
its okay, it was an untold story. It needed to be told. Not a lot of people out there who are interested in a narrative other than the one (self narrative) that runs through their own heads. Its a rare, kind and a beautiful quality, probably born out of a place of compassion.

I am kinda like you that way, i love human emotions. I remember back when i was in Canada i used to work part time as a security guard for this TV show "Suits". Mostly night shifts. Every night i got to meet all sorts of people ( other guards, the filming crew, sometimes the movie extras). Long-haul trucks full of shooting equipment, wardrobe etc, all parked on the streets of downtown toronto. We used to arrive at 9 in the night, and pretty soon the city would go quiet and then it was just us gaurds, trucks and beautiful skyline of the city. We had nothing to pass time ( long 12 hour shifts) but our stories, and i loved it. The darkness of night have this amazing ability of bringing out the most honest and vulnerable truths to the surface. Every one poured their hearts out. Every dream brimming inside, every regret hiding inside, every misfortune that befell and left inerasable scars just flowed through the words and with such ease. It was just such a profound experience. So moving.

No one in my family have ever had any mental health issues. I really cant say what triggered it for me. I did know that i was predisposed to seasonal depression when left alone. The grey bland colour of the sky, on non sunny days, stirred a kind of unexplainable sadness in me. I was most vulnerable when i was alone (which was at home). I remember when i was like 7 years old, i used to tell mom (on one of those days) that i dont know why but i feel like crying. Then i was sent to a boarding school when i was 10, which was a blessing coz you are never alone there. Always surrounded by friends. No time to observe the changing shades of sky. But then the school ended i came back home. Thats when i had my first episode. The transition from a noisy crowded life to the quiet long days of home woke up all the sadness sleeping inside for years. Atleast thats how it felt. I got depressed, and then came anxiety. But soon i was back in grad school and surrounded by tons of friends. Life got back to normal. No signs of depression or anxiety. Like i said Home was the place (and still is) where im the most vulnerable. And we cant run away from home for ever. Sooner or later we have to return. 3 years later i had my second episode when home for a summer vocation. Same trend. First depression, then came the anxiety. Went back to school when the holidays ended and got better (full recovery) with in days. My third episode (4 years later after i came back from canada) was a major one. I got depressed. and the came anxiety. This time i didnt get well. Just got worse and worse from there. You know the rest.

Its kind of strange you know, even now my anxiety is most intense on non sunny days and considerably less on sunny days. fortunately india has a sunny weather most of the year.

A job will be a good start. Put distance between me and my family. Make new friends, wear good clothes, start working out, and the city where i'm hoping to move is full of night clubs, so there's that. It wont solve all my mental health problems but it'll certainly make a big difference. i'll figure out the rest when i get there.

about my english, its just something i picked up along the way. Some of it in Canada (lived there for 2 and a half years), the rest of it from TV shows (i've seen a LOT of them, still do).

How about you? You mentioned growing up in a tough family and neighbourhood, did you manage to move away, somewhere better?

when and how did your life change by your diagnosis? did you find support ( family, friends ? )

Post Edited (ravdeep) : 1/6/2017 5:36:57 AM (GMT-7)

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