My biopsies have been surgical. The first ones were under local, the last one they put me under. Neither were painful. I maybe took a tylenol 3 after each, but that's about it. Mine were breast biopsies, however. The lymph nodes were harvested and biopsied at the time of mastectomy. I'm assuming you're talking about a sentinel node biopsy, and I've never had one done. So sorry you are having to come here for information. I hope someone else will respond to your post who has had a similar procedure.
"There's a difference between a philosophy and a bumper sticker." --Charles Schulz