Kidney problems????Looking for answers.

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Veteran Member

Date Joined Jul 2003
Total Posts : 2921
   Posted 7/12/2005 9:32 PM (GMT -6)   
I was diagnosed with sugar diabetes about two years ago, but my Blood Sugar numbers have never been alarming.  I have taken blood pressure Rx for years which has worked well.  about six months ago my numbers began to climb in both BS and BP.  When I had my physical in March my PCP told me to come back for a blood test in three months.  I did that two weeks ago and got a call from her office to go for a micro urinalysis.  Today was my follow up appointment.  It seems my BS number is up but again not sky high, but the micro urinalysis showed that the micro albumin number which at normal is less than 30, was 743!!! Next step is a 24 hour urinalysis and assuming it shows the same indication I will have to see a kidney specialist.  She keeps saying diabetes causes kidney damage, I know that but I find that so hard to believe since my numbers have not been up until lately. I am thinking those high powered antibiotics I took for a whole year five years ago and a couple of times since for the abdominal wall infection is more likely the culprit if there is kidney damage.
I talked with DebbiR the other day and she told me her BS numbers went up when she changed medication and asked if I had.  My insurance company in all their wisdom did change my BP medication to a generic brand about six months ago.  That IS when the numbers started to go up, so????? I got a Rx for a "brand only" medication to see if that helps numbers to go back down.
I told her I had been so tired and worn out lately it was all I could do to function, so she thought maybe I should try an antidepressant.  I tried Wellbutrin twice and didn't like the feel of it, so she gave me an Rx for Lexapro.  Does anyone have any history with it?
Lots of questions, looking for answers.  And I just talked to Jo-Ann.  She is going to post her news from one of her doctors.  It has not been a stellar day for the Texas girls today.  If you have any answers or suggestions, we would appreciate them, and a few prayers, too????  I tried reading my Merck Manual before posting but found nothing there that gave me answers.
Hugs MK

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Date Joined Sep 2003
Total Posts : 1373
   Posted 7/12/2005 9:42 PM (GMT -6)   
Lexapro and Welbutrin are totally different animals.  The welbutrin is designed to work on a specific pathway, whereas, the lexapro is a combined attack, the good points from both prozac and celexa, both good meds, are combined for this med.  I've heard and seen good results with it.  The side effects happen, at times, your doc probably went over them with you.  If you can hack the beginning transition, try to stick with it for a couple of months.  You won't see anything for a month or so. 
It's no wonder you're depressed with all this medical mischigas going on.  Maybe that change to generic was all it was and this will pass quickly.  Then maybe the reason for the depression will be gone.  Of course, there's always the slugger if you need release!!!!!
Mine's called "Ellen's therapy tool"
"Our greatest glory is not in never falling, but in rising every time we fall." -Confucius


New Member

Date Joined Nov 2004
Total Posts : 4
   Posted 7/12/2005 11:05 PM (GMT -6)   
 Causes, differential diagnoses of Kidney Damage and/or excess microalbuminuria: 




Pyelonephritis is an infection of kidney tissue; most often, it is the result of cystitis that has spread to the kidney. An obstruction in the urinary tract can make a kidney infection more likely. Infections elsewhere in the body, including, for example, streptococcal infections, the skin infection impetigo, or a bacterial infection in the heart can also be carried through the bloodstream to the kidney and cause a problem there.


Glomerular disease is triggered by an abnormal reaction of the immune system. In this case, the body’s own infection fighters mistakenly attack the kidney tissues. Sometimes, an autoimmune disorder such as systemic lupus erythematosus or Goodpasture syndrome is the cause. The attack on the glomerulus may also be the result of an inherited condition. An attack on the glomerulus may also occur after a bacterial infection in another part of the body, such as a strep infection of the throat or skin, the skin infection impetigo, or an infection inside the heart.  




Diabetic nephropathy is called a "silent" problem because there are usually no symptoms in the early stages of the disease. Some of the earliest symptoms include ankle swelling and mild fatigue. Later symptoms include extreme fatigue, nausea, vomiting and urinating less than usual.






The first sign of kidney damage is protein in the urine, which a doctor can measure in microscopic amounts, called microalbuminuria. Small amounts of albumin show up in the urine five to 10 years before major kidney damage happens.






The best way to prevent diabetic nephropathy is to control your blood sugar. In addition, your blood pressure should be monitored frequently, and high blood pressure should be treated promptly. Two types of blood pressure medicines protect against kidney damage in ways that go beyond lowering your blood pressure. These medications are excellent choices for controlling blood pressure in people with diabetes. They include angiotensin-converting enzyme inhibitors (ACE inhibitors) — lisinopril (Zestril, Prinivil), enalapril (Vasotec), moexipril (Univasc), benazepril (Lotensin) and others — and angiotensin receptor blockers (ARBs), such as losartan (Cozaar), valsartan (Diovan) and others. Avoiding medications that can harm the kidneys also can help to prevent kidney disease. However, if you have high blood pressure, microalbuminuria or other evidence of kidney disease, the first line of treatment is an ACE inhibitor or ARB. These two medicine groups are closely related, so the drugs usually are not combined with each other. If two or more drugs are needed to control blood pressure, one of these agents is usually combined with a less closely related medication. ***CAUTION must be used in combining ACE Inhibitors and SSRI and TriCyclic Anti-depressant medications. Their combined use is contraindicated.



A low-protein diet (10 percent to 12 percent or less of total calories) also may slow or halt the progression of kidney disease. If you smoke cigarettes, you should quit. Elevated levels of lipids, such as cholesterol, are associated with kidney damage, so you may be able to reduce your risk of diabetic kidney disease by reducing your cholesterol and other lipid levels through diet, exercise and possibly medication.



Veteran Member

Date Joined Jul 2003
Total Posts : 892
   Posted 7/13/2005 11:18 AM (GMT -6)   
MK, I don't know a whole lot about the situation you're describing. What I do know is that I care about you tremendously. Keep looking for answers. One thing that is pretty clear to me is that the change in meds. caused the uptick in your numbers. When will these ins. cos. recognize that if something isn't broke it doesn't need to be fixed??? Hang in there my friend. Hugs from here.. Luci
In the depth of winter, I finally learned that within me lay an invincible summer.  Albert Camus

Veteran Member

Date Joined Jul 2003
Total Posts : 1294
   Posted 7/13/2005 12:51 PM (GMT -6)   


Yep, the old kidney stuff.  We diabetics really need to be careful as you well know.  The only thing is that sugar levels are the only thing we patients can track.  The doctors have to do the rest.  I also have elevated blood pressure that I take Avapro to reduce.  It seems to be working, but there are so many combinations of medications that cause abnormal readings of all type.  I hope the 24 hour test shows less alarming results and that they can get it all figured out for you.  Someone needs to remind the insurance companies who the doctors are!!!!  mad   Remember you own words, don't worry untill there is something to worry about.

I take lexapro!!!  Yea, yippy skippy.  I wouldn't do without it.  I LOVE it.  It works quickly, no 6 week lead time, and I do not need high doses.  I have taken it for almost three years and it truly helps.  My DD just started taking it and we can already see a difference in her anxiety levels. 

Hang in there dear one.  I have you in my prayers,



 How good is a timely word!  Proverbs 15:23


Veteran Member

Date Joined Jul 2003
Total Posts : 2921
   Posted 7/13/2005 3:08 PM (GMT -6)   
Alright!! Thanks everyone for your input, and especially yours, Candy for personal experience. I didn't realize the Lexapro would begin to work quickly so that is good news. Ellen told me what it is, too, and that was also helpful. I'm not really worrying but a lot of things are adding up a lot better now that I know the test results. My "hips" have been hurting something awful lately and I assumed it was probably arthritis setting in. Now I am realizing that perhaps it was not really the hips at all but the kidneys aching???? I meant to tell the dr yesterday about how hard my belly had been lately and she blew me away with that test result, making me forget....... Anyhow I think I may be collecting fluid there, too, and as I read about all this stuff abdominal fluids can be a problem. You are right, Candy all we can do is track the BS and the BP and I am really being careful and doing a good job for the next week or so to have a good pattern. It will take about ten days to two weeks to get the medication changes because I had to mail the Rx to the ins drug supplier and then have them ship me the meds. She also raised my Glucotrol XL to double, so that will be another change. Meanwhile I am going to take it easy and rest all I can. Good excuse to be lazy, right? I do appreciate the input and help. Hugs MK

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