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New Member

Date Joined Jun 2007
Total Posts : 2
   Posted 6/27/2007 12:06 AM (GMT -6)   
I have had 4 treatments (one every 2 weeks with the last one 2 1/2 weeks ago) of cytoxan (cyclophosphamide) and adriamycin(doxorubicin). My question is that I have not had a menstral cycle since May 18. So, I am 2 1/2 weeks late. I have read that both drugs could cause fertility problems. Is it normal to not have a menstral cycle now? My fear is becoming pregnant. I took 2 tests that were both negative, but I want to know if anyone else has had this situation. Is it normal to miss a period now? I did have one before, but the more drugs, does it cause missed menstral cycles? Any input at all is appreciated. Thanks so much

Veteran Member

Date Joined Jul 2003
Total Posts : 2921
   Posted 6/27/2007 4:11 AM (GMT -6)   
I'm surprised that none of the younger girls have responded to your question. I have not had chemo, but my daughter did and she did not have periods for a good while. I am not sure of details. I feel sure that it is very normal for chemo to stop periods and sometimes, I think, they do not come back. Probably has to do with age and other factors as amount of chemo. Help me here, someone. Welcome to our group, sorry for the reasons you had join us. We seem to be pretty slow this summer. Hugs Mary K. (MK)

Veteran Member

Date Joined Jul 2003
Total Posts : 1564
   Posted 6/27/2007 11:37 AM (GMT -6)   
I was 36 at the time I went through chemo.  I had CAF every three weeks.  I lost my period after the third treatment.  I never got my period back, but some women do.  My onc said I was just on that borderline, and could go either wey.  They really recommend you use birth control religiously for two years after you lose your period and have your homone levels monitored, especially estradiol and FSH levels.  The older you are, the more likely that you will not get your period back.
Of course, hormonal birth control is a big "no-no" now that you've been diagnosed, as is hormonal management of menopausal symptoms.  Some women choose to have a total hysterectomy.  I'm still considering it, but haven't done it yet.  It's a cinch the parts aren't working anymore, after 12 years.  Don't know if this applies to you, but...  A few women go on to have babies after they are diagnosed, but this is a risky undertaking and should be discussed at great length with the doctors to fully understand what your individual risk of a recurrence would be.  A few women also use hormones for menopausal symptoms, as well.  Again, this is something only you and your doctor can decide is safe for you.  There was  a lot of coverage about Suzanne Sommers continuing to use HRT, even though her doctors advised strongly against it.  She seems to be doing okay.  I know that I would never be willing to take that chance.
Hope this helps.
Good luck to you...

New Member

Date Joined Jun 2007
Total Posts : 2
   Posted 6/27/2007 1:13 PM (GMT -6)   
Thanks for letting me join this group.
I am 35 years old and have 3 kids already. I really don't want another one...not at this time especially. Anyway, we did use contraceptive, but it still scares me. I just made an appointment with my doctor for a real test just to make sure. I do feel relieved thanks to your responses. The only cancer in my family was one grandparent on one side had colon cancer and another grandparent on the other side had stomach cancer. So, this whole cancer thing is totally new to me.
Thank you so much for your responses.

Veteran Member

Date Joined Oct 2004
Total Posts : 826
   Posted 6/27/2007 2:05 PM (GMT -6)   
Chemo can definitely stop your cycle.  Depending on your age and how close you are to natural menopause, it may not come back.  I was 44 at the time of diagnosis and chemo.  My period stopped after my 2nd chemo and hasn't come back.  It's been 2 1/2 years.  At your age, it may come back, though.  I would discuss this with your doctor to be sure.
L & H,

Veteran Member

Date Joined Sep 2003
Total Posts : 1373
   Posted 6/27/2007 2:28 PM (GMT -6)   
I didn't see this post until now.  I certainly would have responded.  I had my last period when I started Adriameycin.  I did not become infertile, though.  I thought I was, my doctor thought I was, but I wasn't.  And remember, Tamoxifen makes you MORE fertile, so if you go on it, and even now, do not cease use of any birth control you may be using. 
"Our greatest glory is not in never falling, but in rising every time we fall." -Confucius
Don't knock on Death's Door.  Ring the bell and run.  He hates that.


Regular Member

Date Joined Aug 2003
Total Posts : 137
   Posted 6/27/2007 2:41 PM (GMT -6)   
I was 41 when I started treatment 9 years ago and I went into menopause and never came out. I did tamoxifen and Arimidex and several other chemos. Doctor siad because I was an old younger women I probably wouldn't get it back. Hugs & Payers Cyndy
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