I was diagnosed with fibro/cfs in 2001 by my MD. I have used natural herbs/cleanses and some kill bacteria. I always notice when I do these cleanses and stick to a low carb, sugar free, healthy diet, my fatigue levels, brain fog, body pain is cut in half or therabouts. Definitely pathogens are a factor in fibro/cfs if I go by my experience and the research I've done from many sources. I don't know if a single bacteria is the originating cuase, but I could see how taking a medication that kills pathogens woudl make a huge difference just because I've seen how taking herbs that kill pathogens has made such a big difference for me.
Hold onto hope and follow your instincts.
The son of my friend's friend is studying to become and MD and I e-mailed him a couple times. He thought that leaky gut (gut permeability) played a big role in fibro. I have thought before of trying to treat this - I did take L glutamine for awhile and usually take probiotics. I didn't notice any real different that I'm aware of whiel doing these things solely. But I think that is because I had a few issues to address. I am just wondering, if one were to address gut permeability as you suggested, do you know how long it is normally needed to take these supplements for the gut to repair itself? I think that is an interesting connection you pointed out re. the endotoxins and brain fog. Thank-you for taking time to share.