I know this is an old post but yes, I think there can be a connection for some people. I've had chronic fatigue for many years, as well as some digestion problems (abdominal pain, C/D, lower right ab bulges out). Finally about 6 months ago I started trying to solve the problem after years of just dealing with it. First few docs were worthless, tests were normal, tried tons of supplements/diet changes to no avail.
Finally went to a gastro. Turns out my colon has been inflamed, pseudopolyps formed and everything. So yes I think the chronic fatigue has been bowel related in my case: inflammation has been draining my energy plus interfering with nutrient absorption. Doc prescribed anti-parasitic, anti-inflammatories and probiotics, so we'll see if that does it.