Morphine XR vs. Oxycontin

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Melanie50
Regular Member


Date Joined Oct 2005
Total Posts : 148
   Posted 1/25/2008 10:27 PM (GMT -7)   
Hi everybody!  I haven't been on for a few weeks.  My pain has been at the 8 to 9 level.  On Monday and Thursday next week I'm receiving Caudal shots at my Pain Management Clinic.  They worked for awhile the last time I had them done.
 
However, my main question is which is stronger - Morphine XR or Oxycontin XR?  Right now I'm taking 150mg of Avinza, percocet for BT pain and my doctor just added a muscle relaxer, Robaxin.
 
Does anyone know if morphine and oxycontin are equal in their effects or is one better than the other.
 
Thanks all!!!
yeah   tongue yeah tongue yeah

Degenerative Disc Disease, Spinal Stenosis, Herniated Disc, Arthritis of the Spine, some kind of problem with the L5-S1 area, sciatica, diabetes, depression and anxiety.
 
 
Lord help me to remember that nothing will happen to me today that you and I can't handle together.


Chutz
Veteran Member


Date Joined Jan 2005
Total Posts : 9090
   Posted 1/25/2008 10:59 PM (GMT -7)   
Hi Melanie,

Oxycontin extended release is about twice as strong as morphine extended release tablets. The medical literature says the ration is 2:1 oxy to morphine. Some literature says its 1.5:1 and other places list 2.5 to one. When my doc just switched me over he's using the lower ratio to start with. I've been on 80mg of oxy/day and he's moving me to 120mg of morphine/day. Both are extended release. Just realize that any drug will work differently for each person. I'm making the switch this weekend. Have my fingers crossed. The choice wasn't mine. See related post on Insurance company forcing me to switch.

Hope this helps,
Chutz
Co-Mod Fibromyalgia & Chronic Pain Forums
~~~
Fibromyalgia, Ulcerative Colitis, Insulin dependent diabetic, collapsed disk, dermatitis herpetiformus, osteo arthritis in spine and other locations.
***************

The only difference between genius and stupidity is that genius has it's limits. Albert Einstein: (1879-1955)


volfan
Regular Member


Date Joined Nov 2007
Total Posts : 58
   Posted 1/26/2008 11:32 AM (GMT -7)   
Hi Melanie and Chutz,
A doctor friend of mine recently told me that OC may be stronger but a person will need more and more of it as time goes by. I guess one builds up a tolerance to it. He believes that other drugs are better suited for long term pain control. He mentioned drugs like Kadian, Morphine Sulfate, and Methadone. He mentioned several other names which I cant remember how to say much less spell. Iv'e been on Kadian and Morphine Sulfate which worked for me but still needed Percs for BT pain.
Thats my two cents worth!
Have a Blessed Day!!

Centurion
Regular Member


Date Joined Jan 2008
Total Posts : 28
   Posted 1/30/2008 3:24 AM (GMT -7)   
True you will need more and more but who wants to live with pain...there are points when pain gets so bad youd do jsut about anything..and if theres something out there where you can get atleast 1 day of being pain free...Id do it...I have been on OC for about a year and a half and have only upped my dose once...So i mean as long as you take it as prescribed then you should be alright...

hazelB
Regular Member


Date Joined Jan 2008
Total Posts : 114
   Posted 1/30/2008 5:05 AM (GMT -7)   
I do agree with centurion, you may need more and more as time goes on, but I tried avinza and it wasnt as successful as oxy. For me personally, I would rather take a med that knocks down the pain better and risk having to increase it in the future than take something that would cause me to have to take more BT pain meds. I've been on oxy for two years and only upped it in the very beginning when they relized it want going to manage my pain fully. But for the most part its done its job for 2 years. But even if it does lose effectiveness a pm doc will usually try to fill the holes with a BT med to avoid raising it.(the rule of humc is if you need more than 3 doses of BT pain meds then your on the wrong med or dose, but thats only the rule of thumb) They know that raising it too often will mean a med change sooner and your tolerance will become too high leaving you with fewer options. But your body will build a tolerance to anything including anti-depressants and anti-biotics, so in the long run anything is going to need to be increased or changed.
 Interstitial Cystitis and Endometriosis


Melanie50
Regular Member


Date Joined Oct 2005
Total Posts : 148
   Posted 1/30/2008 9:25 AM (GMT -7)   

Thank you everyone.  The avinza just isn't cutting it anymore and I'm up to 150 mg a day.  I'll talk to my pm doc when I go in.

Just this past Monday I went in for the first in a series of caudal shots.  I feel pretty good today - pain is minimal.  I get another one tomorrow.  They've worked in the past - although it doesn't last too long.  However, I'd go through just about anything to have a day or so of pain free living. yeah


Degenerative Disc Disease, Spinal Stenosis, Herniated Disc, Arthritis of the Spine, some kind of problem with the L5-S1 area, sciatica, diabetes, depression and anxiety.
 
 
Lord help me to remember that nothing will happen to me today that you and I can't handle together.


Centurion
Regular Member


Date Joined Jan 2008
Total Posts : 28
   Posted 1/30/2008 8:33 PM (GMT -7)   
The main problem is that in most of the Docs ive seen is...everyone who walks into the door is an addict in their eyes and this is only a bandaid on a stab wound....but those who dont live with constant pain dont understand...and like ive been told for almost 2 yrs know...get surgery...thats not the solution...Unlike most people..I met with a few surgeons and interviewed a bunch of people whove had the surgery and about 80% of them are worse...even if you get a year of releif they all end up worse then they were before...So i said no thanks...If your not happy with the care your getting..go somewhere else...no doc is ever going to know your body and what works for you as well as you do...

drjimmy
Regular Member


Date Joined Dec 2008
Total Posts : 110
   Posted 12/6/2008 2:33 PM (GMT -7)   
Hello all. I have been treated with Percocet (Oxycodone APAP) for years. However my pain has progressively gotten unbearable and not responsive to Percocet. I saw a doctor at a pain clinic in Philadelphia and he prescribed oxycontin ER as well as Oxycodone APAP. However, my insurance company declined to pay for the Oxycontin, until I jumped through some hoops first. They wanted me to first try Morphine Sulfate (MS Contin). If that didn't work, then we needed to try Fentynyl Patch. Finally if these failed, they say they will pay for my oxycontin. My doctor started me at 15 MG of MS Contin (Morphine Sulfate) along with 40 MG daily of Oxycodone. Over the course of a few months, I'm now at 130 MG of MS Contin along with the 40 MG of Oxycodone. However my pain is not improved, it's excruciating. I was wondering if it was still worth trying the Oxycontin, since Morphine is pretty strong and yet isn't getting rid of the pain. According to what I think I've read here, Oxycontin is twice as strong as MS Contin and is therefore worth trying. If I've misunderstood something, or if someone has any advice, please let me know, Thank you for all the information you are providing. It's comforting to know I'm not alone and that other people are going through what I'm going through. Other than my wife, no one in my family knows what I go through every day. I have very little quality of life. My pain is constant, all day every day. I'm hoping for some relief from Oxycontin along with oxycodone. Good luck all.

Pamela Neckpain
Veteran Member


Date Joined May 2008
Total Posts : 1821
   Posted 12/6/2008 3:21 PM (GMT -7)   
Just a quick note --

I've taken Vicodin, Oxycontin, Fentanyl Patch, Morphine Sulfate, Avinza and
hmmmm ... (Memory is shot!)

The only thing that works for me is Methadone. Methadone doesn't work
very well. Of course, everyone is different.

That's my penny's worth.

Pamela
MEDICAL CONDITIONS

Osteoarthritis all levels of spine right down to Coccyx,Spondilytis,Myofascial Pain
Fibromyalgia,Bulging Discs,Spinal Stenosis,Scoliosis,Osteopenia,Chronic Constipation
Carpel Tunel Syndrome, Attention Deficit Disorder,
Depression & Anxiety

Methadone for Pain, Xanax for Anxiety, and more, of course.


tmjpain
Veteran Member


Date Joined Oct 2008
Total Posts : 2021
   Posted 12/6/2008 7:15 PM (GMT -7)   
Percocet is Oxycodone with Tylenol.
 
Oxycontin is Oxycodone with a continuous release. So what makes this so different or so much stronger? What is the ingredient that is different.
 
Why would I have terrible side effects from Oxycontin and be ok with percocet?
 
Would you expect to have withdrawal if I had been on Tramadol for five months then stopped that and was put on oxycontin. The tramadol wasn't working anymore so my PM dr. put me on Oxycontin and I had all kinds of side effects (it was just like withdrawal I would say, that's what it seemed). So I stopped the oxycontin because I was in a terrible way with the side effects and went back to percocet prn. I can sleep better now with being on Imovane (sleeping pill) and Flexeril (muscle relaxant) at bedtime. With a better sleep at night I have more strength to cope with the pain in the day and just use percocet as necessary. Although I still have pain in the day I can handle it better on a good night's sleep. Is that confusing??
 
Sorry for carrying on. Just trying to figure this out.
 
Thanks for listening. Here's to some pain free days (or less pain) for all of us!!

drjimmy
Regular Member


Date Joined Dec 2008
Total Posts : 110
   Posted 12/6/2008 7:34 PM (GMT -7)   
From what I know, the difference between Percocet (AKA Oxycodone APAP) and Oxycontin is 2 things. The main ingredient in both is oxycodone. Percocet is Oxycodone with Tylenol (APAP). Oxycontin is Oxycodone without Tylenol, and it's an Extended Release/Controlled Release. So rather than taking a Percocet every 4 hours as needed for pain, you would take Oxycontin a pre-determined number of times a day, whether you are in pain, or not. This keeps the Oxycodone at a constant, stable level in your body. So I share in the confusion of a previous post: If Oxycontin is just Percocet Extended Release and without Tylenol, then why is it considered so much stronger than regular Percocet? Is it the fact that there's a more stable constant level of the pain fighting ingredient? What are the starting and maximum MG/Dosage that a doctor can prescribe Oxycontin? Also, I'm surprised that my doctor tells me it's ok to take Oxycontin & Oxycodone at the same time. Meaning I would take Oxycontin however often he orders me to and in addition, I would take Percocet every 4 hours as needed for pain. Is anyone else in the same boat with this medicine regemin?

kttn251977
Veteran Member


Date Joined Jul 2007
Total Posts : 554
   Posted 12/7/2008 11:43 AM (GMT -7)   
Hi Melanie..... I was on avinza & kadian with no luck. I tried methadone before oxy, but where I go they will not prescribe a BT med along with methadone. So it wasn't enough for me. Though methadone is a cheap alternative. The extended release Oxycontin has a lawsuit against anyone having a generic form, so it is quite expensive. For awhile I had lost my insurance & was paying almost $600 out of pocket for the med. But I stand by the medication, I think it works well. At first I was put in a low dosage of oxycontin (10's I think) & have gradually gone up to oxy 80's. I can tell a big difference in the two. ER morphine just didn't seem to work. (I also build up a tolernce quickly.) I was, until this month, on oxycontin & oxycodone (for BT pain). They are both basically the same medication except of course, they oxycontin is released within a 12 hour time. I was very afraid to go on oxycontin with all the hype to the medication. I have had only one issue & frankly it is severe constipation. I take senokot (its OTC) laxative. There are a few different kinds & the overnight name brand works best for me. As long as you don't abuse the medication, there is nothing to worry about. I do not have any fuzzy or sleepiness from the med. (again I have a high tolerence for pain meds) When I feel something isn't working as well I don't change all my meds at once, my dr had told me on the 1st visit that everyone is different & it may take years to get the correct formula for me. For example, last month the BT oxycodone was not working as well for me anymore, so we decided to try dilaudid for BT pain. I have been on it about 2 weeks with zero results. (You will eventually be able to tell.) So now I know dilaudid does not work for me. Thats why I change my meds slowly and one by one. This was my last resort since I have not only had about half the pharmacy- but I am allergic to an ingredient that is in most pain & regular medications. (I am actually going to have a pain pump trial next month.) As for the oxycontin, it has a bad rep because of people who abuse it. Occasionally it does make me nausieted, so it may be a good idea to have a script of phenergan as well. Just incase. But, I think the drs can call that one in though. I did read it was a common side effect. I think it is a great medication. It has done well for me. I have been on oxy (different doses) for about a year & before that nothing would last longer than 3-4 months. If you have any other questions, feel free to ask. I will try & answer them the best I can!
RX's: Oxycontin 80 MG 2x's daily; Dilaudid 8 MG 4xs daily; Zanaflex 4mg 3x's daily; Restoril 15mg 1x; Soma 3x's daily; Lyrica 100 MG 3x's daily (pain & fibro.); Phenergan 25 MG (as needed); Amitriptyline 25 MG 1x (chronic pain); Cymbalta 60mg 2x's daily (pain from fibro); Metoclopram (as needed) & Senokot (as needed).
"The most critical choice you'll ever make is the one you make about what you're going to do with this. The past is over. The future hasn't happened yet. The only time is now."
- Dr. Phil


LKEPOW
New Member


Date Joined Jan 2009
Total Posts : 4
   Posted 1/24/2009 12:25 PM (GMT -7)   
 
 Good Morning,
 
 To start off, I am new to the site and I am amazed to see how many people have the same questions that I do..
I have Lymphoma it's in my upper r. breast and armpit, the pain is bad but I do not tell my husband only my Dr. I was on morphine, and then out of the blue he switched me to oxy 80 mg. Can anyone tell me what the side effects will be going threw this?
I was raised not to even take an aspirin, if that tells you anything, and I did try it the holistical way, but it has gotten that bad, and surgery will not be for awhile yet.
GOD BLESS ALL OF YOU...
                                                 Layna

drjimmy
Regular Member


Date Joined Dec 2008
Total Posts : 110
   Posted 1/24/2009 12:59 PM (GMT -7)   
Layna, I am very sorry to hear about what you're going through and the pain you're in must be real rough. I have been on Percocet for over 10 years and have had no side effects, nor ANY indications of addiction or dependence. I have not tried Oxycontin yet, except the very lowest dose, and then my insurance company wouldn't cover it. I'm now about to try Oxycontin, since I jumped through the hoops my insurance company wanted me to jump through. Hopefully someone else who has been on Oxycontin can discuss any side effects you may encounter, but I would assume it would be similar to Percocet, since it's the same chemical, only without tylenol and in an extended release form. I have been married for 7 plus years and I couldn't get through my pain and disability without my wife's constant love and support. I can't imagine not telling her about pain I'm in, especially when the pain is as bad as you describe. You shouldn't suffer alone...You should be able to share this with your husband. If you're not telling him to protect him, don't do it. Marriage is for better or for worse and you need to be able to lean on your husband for support. I know my wife would be upset with me if I hid my pain or feelings from her. I wish you well and it seems we'll be starting on Oxycontin around the same time. Let's hope it works for both of us. Take care...byeeeeeeeee
 
Eric

LKEPOW
New Member


Date Joined Jan 2009
Total Posts : 4
   Posted 1/24/2009 1:25 PM (GMT -7)   
 
 
 Dear Eric,
 
  WOW ooooooook you really hit the nail on the head, how  you could guess that I don't know, see we had been dating for 5 years and just got married on my Birthday this past Sept. he works 6 days a week 10 hours a day, and if he knew what I felt< I know him, he couldn't handle it.. Keep in mind he was the one who found the lumps not me..
Anyway, so when you hit that, it did bring tears to my eyes, because I DO tell him everything, I just CANT tell him this, as I do know I can FIGHT this and I WILL WIN...
I admire you for being so strong and know that what you just told me, was what I really needed to hear...
I thank you so much...
The best of wishes..Layna

 
 
   LAYNA


Hound-Dog
Regular Member


Date Joined Oct 2005
Total Posts : 182
   Posted 1/25/2009 12:50 AM (GMT -7)   
This Spring will make it 10 years that I've had to take narcotic pain killers so I can stand and walk with short crutches for small periods of time.I'm thankfull that the extended release morphine as my base pain killer, works best for me because it's cheaper in comparison to Oxycontin and has been around for a long time now with a lot less bad PR than Oxy.


SmurfyShadow
Veteran Member


Date Joined Dec 2008
Total Posts : 2386
   Posted 1/25/2009 11:46 AM (GMT -7)   
Mel--Neither if you can stay away from it would I recommend. It can suppress your system and make you at risk for respitory infection

Tm-Why? Its because of how the medication is released. The stregth of dose, how often it goes, who makes the pill.
 
Smurfy Shadow
 
DX: Wegener's Disease, Migraines, Diabetese Type II, PCOS, Lactose Intolerant, Benign Heart Murmer, Asthma, Asperger's Syndrome, Necrotizing Gramultous Inflamation in eye, A.D.D., Acid Reflux
 
Medications: Imuran, Prednisone, Tri Nessa, Percocet, Metformin, Prilosec, Protonix, Zantac, Advair, Cingulair, Albuterol, Calcium + Vitamin D


Hound-Dog
Regular Member


Date Joined Oct 2005
Total Posts : 182
   Posted 1/26/2009 4:50 PM (GMT -7)   
SmurphyShadow, I agree 100%. One should only get involved with painkillers if they can't maintain a reasonable "quality of life" without them.

LKEPOW
New Member


Date Joined Jan 2009
Total Posts : 4
   Posted 1/28/2009 8:24 PM (GMT -7)   
Dear Smurphy,

I do agree also, however I have been on perocet 10/325 for going on 5 or more years, and then when this cancer came, ok let me back up, the reason for the percocet was I had female cancer I got that cleared and then it went to my lower intestines just this past year, and now just in Sept, my husband had noticed a lump on my upperleft shoulder area but near the breast, I WAS cleared of breast, BUT then after the MRI and other test, I got a certified formal letter from the radiologist saying that I had Lymphoma...so just lately is when they started the morphine, I couldn't take it as it made me itch very badly, sooo now this past Monday they started me on oxy 40 take 2 tid and I found out that I cant handle all of that and the Dr. did say when I called to tell him that it was way to much, """then take when I need to "" so that put me at ease..


...Have a great evening everyone..
 
 
   LAYNA


Scarred_for_life
Veteran Member


Date Joined Jul 2008
Total Posts : 1559
   Posted 1/29/2009 5:27 AM (GMT -7)   
LK; I admire your strength through this tough time. I know that when I was diagnosed with cervical cancer I was devastated, alone and totally freaking out thinking that there would be no one to raise my young son. Luckily enough they caught it early enough that I did not have to go through the pain of Chemo or any of that and they were able to get everything out. I had my family there but they were really no support. My sister was dealing with her family....my brother his own....my mom was into her own life so I was pretty much a single mom trying to deal with a life altering event raising a 9 year old boy. When I tried to approach my family with real facts that if this was going to go the other way and end my life and what my last wishes would be they would not listen. They thought that I was being over dramatic and told me I was being stupid that nothing was going to happen to me. So I was left with no way to convey my last wishes but by writing them down. But here I was faced with another problem....I knew that they would be overlooked if anything did happen to me. So it was about this time that I was dating my soon to be husband. I conveyed to him my feelings...poured out my heart to him and he did not criticize or tell me I was being too dramatic. He listened and then he did something that shocked me. He took me to a notary and that piece of paper that I had filled with all of my wishes he told the notary exactly what it was that I wanted. The notary understood and told me that even if it is just a piece of paper written with a few simple requests that a person desires in case of their death, as long as it is notarized it is a legal binding document in the state that I lived in.

Well I was happy about this and it put my heart at ease. I still have that paper but things have changed a bit. A Legal Will will be drawn up here in the next few years to convey to our children our desires so that everything is clear. I guess the reason I am telling you all of this LK, is because I couldn't turn to my family when I needed them to most. They did not want to deal with the realization that their own daughter or sister might be actually dying. But.....there was someone I could trust and I have trusted him ever since. He knows everything. I have anything going on with me he knows....I keep no secrets from him because I believe that not only does he deserve the respect to help me figure things out and be by my side through the good times and the bad but he also is my husband and when I said "I do" we became one.

I think your husband deserves to know that you are sick hun. He is after all with you through it all no matter what. I know you think that you need to be strong alone but wouldn't it be better to have him to lean on? I really think the two of you can handle whatever comes down the road if you hang onto one another together. Anyway....good luck hun. Hope you are well.

Scarred
HEALTH ISSUES: Herniated discs at S-1-L5, L5-L4, L4-L3. Two level fusion (2000); one level fusion (2002); Revision at L4-L3 (2003). Slight herniation at L2-3 but Neurosurgeons will not operate because of previous failed surgeries. Diagnosed with Failed Back Syndrome, Permanent Nerve damage and Chronic Pain

Medications:

Kadian, Lexipro, Percocet, Lunista, Topamax and Robaxin.


LKEPOW
New Member


Date Joined Jan 2009
Total Posts : 4
   Posted 1/29/2009 12:32 PM (GMT -7)   
 
Dear Scarred,
 
   O my, I am so very sorry  to hear about your health problems, I myself went though that when I was 22 thank the Dear Lord I had already had my 2 children..
But, I must make one thing clear, My husband DOES know that I am sick, oooooooo yes he does, what the issue was he doesn't know about the pain, Im so sorry that I did not clarify that in earlier post. so please forgive me.
   I just could NOT tell him about the severity of the pain because I know him well enough to be the wonderful man he is and he would be just devastated, I know he would take an earlier retirement,
""" He builds casino's here in Vegas"""" which when we found out about the Lymphoma he bought up immediately, and I told him not to as he would definitely regret it, and I also told him that I would be fine here at home..
 A couple of weeks ago, I did purchase a walking cane to help me get up out of bed, and as I excepted he was very sad to know that I had to have help getting out of bed, Im only 115lbs but at night my insides harden like concrete..
Ok, as I said Im so sorry that I did not clarify that in my earlier post, but yes it was about the pain....
I thank you for telling me your thoughts and do feel free to talk if you ever need anyone to talk to..God Bless..
 
Medications :::Estradiol, Percocet, Oxycontin, Lorazapam
 
 

 
 
   LAYNA


WINDYGOOSE
New Member


Date Joined Nov 2011
Total Posts : 2
   Posted 11/20/2011 10:39 AM (GMT -7)   
I have been taking oxycotin 40mg's ER twice daily, along with oxycodone 15mg's 1 to 2 tablets every four hours not to exceed 8 a day.  I originally started out with tramadrol, which did nothing, so went to percocet 10/325, that worked for a little while but the job i was doing was hard on my back, oh yeah that is why i am taking the medication, my back is in bad shape.  Which i believe happened while deployed to iraq.  Never had back problems enough to see a doctor, just average soreness as i got older, the work i did, the gym, and just working in the yard.  The soreness always went away.  Back to the medication,  the percocet didn't really work anymore, so i was prescribed oxycodone 15mg's 1 every four hours.  That worked good, but still had pain, so i kept the same strength just went up in the amount to take every four hours 1 to 2 tablets.  So i seemed to have the right amount but it didn't last the four hours, so i was prescribed the oxycotin 40mg ER, along with the oxcodone.  That has been working good.  I lost my military insurance cause i couldn't make the monthly payment.  I just went to the VA and they said they don't carry oxycotin, and would subsitute it with the morphine sulfate ER.  What can i expect with that change?  I am not sure of the dosage i will get it this coming week.  Let me know what you think, i appreciate it.  I have never tried the morphine XR (sulfate).

straydog
Forum Moderator


Date Joined Feb 2003
Total Posts : 11529
   Posted 11/20/2011 2:55 PM (GMT -7)   
Hi WindyGoose and welcome to Healing Well's chronic pain forum. I am glad that you found us but sorry that you have to be here.

I cannot tolerate Morphine so I cannot answer your question that you have posed here at the forum. I would suggest that you either ask your dr or even call your local pharmacist. Either of the two can you the correct information you are needing. Switching over medications can really be a pain in itself at times.

WindyGoose I am going to ask you to start your own intro post here at the forum that way all the members can see it and respond and welcome you aboard. Many times they see an old posting such as this one, they will ignore it and go on to the next one.

If you will look on the left you will see Post New Topic, click there and then a heading areaa will show up, you can type something like new member has questions about pain meds and from there it will take you to the heart of the posting area.

Again welcome aboard and keep posting and let us know how you are doing. Take care.
Moderator Chronic Pain Forum

spinal soldier
Veteran Member


Date Joined Dec 2009
Total Posts : 628
   Posted 11/20/2011 7:42 PM (GMT -7)   
the jury is still out if oxycodone is more of a kappa-opioid receptor agonist than a mu-opioid receptor agonist like morphine is the standard. if i had my choice i would go with a higher dose of morphine unless your pain is neuropathic in nature because studies with oxycodone seem to have a good effect with that. i have noticed a hyperalgesia i guess you would call it with oxycodone because it seems to create hypersensitive nerves with me and many other patients i have known.
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