I know from personal experience, that taking some of the antidepressants, like Pamelor, caused a difference in my depression. I don't take that drug anymore, but for years, my doctor insisted I get brand name because the generic was not as effective. I take generic percocet for pain and it works the same as the brand name for me.
As for the OTC drugs, I find the generic works pretty well for me. Cold remedies, ibuprophen, aspirin and acetominophen work pretty much the same as the brand names.
I guess its safe to say that generics are good. They are less expensive and work fairly well. There are exceptions and doctors can help you out there.
Good luck and God bless.
Moderator Chronic Pain
Believe in yourself. Be kind to fellow humans and animals. Take time to smell the flowers and the coffee.
And by all means, when you are down, ask me for help. I will be there.