Kadian/ Avinza

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Lynn
Regular Member


Date Joined Jan 2003
Total Posts : 492
   Posted 6/28/2008 9:44 AM (GMT -7)   
At my last monthly visit with PMD he gave me literature on both of these drugs and wanted me to check with my insurance about coverage etc. I am 100%
all for extended relief medication however, I am concerned about the step up from Oxycodone to Morphine based medication. I worry about the future and surgery etc. If I step up now will anything work later? While I am probably jumping the gun about surgery I am just trying to be realistic, my surgical record is staggering when you really think about it. Early appendectomy at age 4 and exploratory surgeries not listed in my signature along with C-Sections all in all 10 abdominal surgeries. Now, I am faced with possible surgeries for wrist now and later hip...
I am scared of moving up the medication ladder but I am also scared of how much oxycodone it takes to make me comfortable enough to get out of bed and move during the day.
I guess I would like to know from you that have taken the step up if I am maybe over-reacting?
If those of you who have experience with these drugs.... do they work well for you?
As with all ... I do understand some work for one person and not another.
Anything you can pass along to me to help me make a good decision is most greatly appreciated.
Best of Health.. Lynn
Dx'd with crohn's 1983, resections 83,85 and 89 Double Strictureplasty 2005, Dx'd COPD 2000, Psoriasis 2002 and Fibromyalgia 2005.
Currently takeing Humira, Pentasa, Lomotil, Elavil, Sinemet, Skelaxin, Advair, Abuterol, Oxycodone and Xanax as needed


hurting
Regular Member


Date Joined Jun 2008
Total Posts : 59
   Posted 6/28/2008 4:01 PM (GMT -7)   
hi lynn---
 
i'm new to this particular site, but thought i'd throw my two cents in about kadian.  i have been taking kadian for about 2 weeks; so far, so good.  i started @ 10mg. once a day w/ norco for bt pain.  my current schedule is:
 
1 kadian (10mg) twice a day
1 750/750 vicodin 4x's a day prn
1 .25 xanax 4x's a day prn
searching for an antidepressant
 
before i switched to the kadian, i was on the fentanyl patch....I DO NOT RECOMMEND THE PATCH TO ANYONE!!!  nono fentanyl is the generic, duragesic is the brand name.  the withdrawals were excruciating and the patch in general made me an emotional trainwreck.
 
also...if you DO decide to go forward w/ the kadian, another chronic pain site i visit forwarded me to kadian's website, and you can get a card in the mail ( i got mine yesterday) for "co-pay assistance up to $50/month.  my copay is only $30, but now it is free until the end of this year.
 
hope that is helpful---wishing you a pain free day---
k
 
3 bulging discs in low back and DDD

hurting
Regular Member


Date Joined Jun 2008
Total Posts : 59
   Posted 6/28/2008 4:20 PM (GMT -7)   
oh yeah..forgot to add that it does not make me feel buzzed, high or sleepy which was a big worry for me...wasn't looking
for any of that...just good pain relief.
 
-k

Lynn
Regular Member


Date Joined Jan 2003
Total Posts : 492
   Posted 6/28/2008 5:01 PM (GMT -7)   
thanks for sharing k, any info is good to know. also good to know that I will be able to function if I decide to take the step. I cannot be altered as I care for my aging Mom who has dementia and is in congestive heart failure.
Dx'd with crohn's 1983, resections 83,85 and 89 Double Strictureplasty 2005, Dx'd COPD 2000, Psoriasis 2002 and Fibromyalgia 2005.
Currently takeing Humira, Pentasa, Lomotil, Elavil, Sinemet, Skelaxin, Advair, Abuterol, Oxycodone and Xanax as needed


hurting
Regular Member


Date Joined Jun 2008
Total Posts : 59
   Posted 6/28/2008 5:05 PM (GMT -7)   
I know whatcha mean, lynn...i'm caring for two very active children 13 and 9.  i CANNOT and will not take a chance with them or anyone else i'm caring for w/ side effects from meds.  good luck...please keep me posted; i'm curious to know the outcome.
regards--
k

Lynn
Regular Member


Date Joined Jan 2003
Total Posts : 492
   Posted 7/3/2008 6:49 PM (GMT -7)   
I took the advice of my PM doc and we started Avinza today. 60mg once a day and percocet for breakthrough. He was a bit concerned about the holiday weekend coming up and making such a big medication switch, he made sure I knew who to call if I had problems that I couldn't deal with. He explained it was not going to be magic and it would take an adjustment period to build up the medication in my system so it could take about a full week for it to truly begin to do the job it is made for. I am keeping fingers crossed. So far I do not feel drugged or dopey so this is a very good thing. I will keep posting as the days pass just incase someone else may end up with this big decision down the road.
I am praying it will work, and work well.
best of health
lynn~~
Currently takeing Humira, Pentasa, Lomotil, Elavil, Sinemet, Skelaxin, Advair, Abuterol, Avinza, Percocet and Xanax as needed


Lindaloo
Veteran Member


Date Joined Sep 2006
Total Posts : 1713
   Posted 7/4/2008 7:23 AM (GMT -7)   
Like you said, these drugs work differently on different people. For me Kadian and Avinza was a horrible mistake. I took Avinza most recently and boy did I have a bad side effect. For the next 24 hours I was awake with awful tightening up of my muscles that would not go away. I stopped the drug immediately, and like I said, after 24 hours, I was OK again. Hope you have better luck since you say you just started it.

Keep us posted and let us know how you are doing.

Lindaloo
Moderator Chronic Pain
 
Believe in yourself.  Be kind to fellow humans and animals.  Take time to smell the flowers and the coffee.
And by all means, when you are down, ask me for help.  I will be there.
 
Linda


Lynn
Regular Member


Date Joined Jan 2003
Total Posts : 492
   Posted 7/5/2008 4:08 PM (GMT -7)   
Lindaloo,
Today is day 3 on the Avinza and no cramping of muscles like you experienced. However..... I do take Skelaxin 3 times a day which is a muscle relaxer because I had such terrible Charley horse cramps in my calf's and in my feet. Not sure if this is preventing the same reaction you had or not but at least for now so far so good. Also, no trouble sleeping either.
best of health
lynn~~
[color=purple>Dx'd 1983 Crohn's Disease, COPD 2000, Psoriasis 2002, Fibromyalgia 2005 along with Cronic Inflammatory Disease 2005. Currently takeing Humira, Pentasa, Lomotil, Elavil, Sinemet, Skelaxin, Advair, Abuterol, Avinza, Percocet and Xanax as needed[/color]


Lindaloo
Veteran Member


Date Joined Sep 2006
Total Posts : 1713
   Posted 7/5/2008 6:13 PM (GMT -7)   
Glad to hear it Lynn. Hope it continues to work for you then.

Lindaloo
Moderator Chronic Pain
 
Believe in yourself.  Be kind to fellow humans and animals.  Take time to smell the flowers and the coffee.
And by all means, when you are down, ask me for help.  I will be there.
 
Linda


hurting
Regular Member


Date Joined Jun 2008
Total Posts : 59
   Posted 7/6/2008 8:06 AM (GMT -7)   
Yay! Lynn---
 
Glad to hear things are well with the Kadian.  I'm having good luck with it as well.  I take it 2x's a day and try to take my last dose right @ bedtime so that i can get the 7 hours or so that it REALLY lasts of quality sleep.  use my bt meds for the time throughout the day as needed.  i see my pm doc on tuesday...anyone have any advice?  i'm RX'd the kadian 2 x's a day and up to 4 vics prn.  i've really needed the 4 vics daily, but that's all...the kadian AND the vics prn are doing the trick...i don't really want to up the kadian dose...do  you think he'll be ok w/ that or will he wanna up the kadian to have less bt?  just curious.
hope you're all having a great weekend!!!
-k

hurting
Regular Member


Date Joined Jun 2008
Total Posts : 59
   Posted 7/6/2008 8:29 AM (GMT -7)   
oops... eyes ust reread your post and saw you were taking avinza...what's the diff between kadian and avinza? 
-k

Lynn
Regular Member


Date Joined Jan 2003
Total Posts : 492
   Posted 7/6/2008 7:13 PM (GMT -7)   
Kadian is taken 2 x daily while the Avinza is 24 hour pain relief. I would discuss the dosage with your doc and ask him what he thinks would be best. I personally think the less pills I have to take daily the better for me. Right now I am taking the percocet pretty regular 1 every 8 hours. I am going to try to begin skipping the daytime pill and just take one in the morning and one at bedtime probably on Thursday. I figure the Avinza should be pretty level in my blood stream by then and hopefully it will work out for me that way.
Good luck with your PM visit!
Best of health
lynn~~
[color=purple>Dx'd 1983 Crohn's Disease, COPD 2000, Psoriasis 2002, Fibromyalgia 2005 along with Cronic Inflammatory Disease 2005. Currently takeing Humira, Pentasa, Lomotil, Elavil, Sinemet, Skelaxin, Advair, Abuterol, Avinza, Percocet and Xanax as needed[/color]


tom inpain
Regular Member


Date Joined Jul 2008
Total Posts : 239
   Posted 7/8/2008 4:28 PM (GMT -7)   
Hi Lynne: I am brand new to Healing Well. I have recently been placed on Kadian and have been on it for about two weeks so far so good. I use Norco for break thru pain. I have failed surgeries for my neck which was totally fused. Also have meralgia parastica in my hips from the bone graft for my neck. plus
Iam on my second total knee replacement. My life is nothing bur pain and discomfort. Hope You feel better Tom

hurting
Regular Member


Date Joined Jun 2008
Total Posts : 59
   Posted 7/8/2008 7:03 PM (GMT -7)   
Hi Lynne---
 
saw my pm today and i'm just feeling perfect with the kadian and vicodin for bt.  thanks for the info on avinza...the kadian is supposed to be 24 hours also...i take 10mg in the am and 10mg when i go to bed w/ vic prn.  since i just came off the fent patch, i don't want to make YET another switch since i'm so pleased with my relief thus far.  i'll keep the avinza in mind should it become necessary.  hopefully with some quality pt, i'll get this taken care of.  i hope to not have to take meds for the rest of my life; i guess time will tell.  hope you are all well!
 
-k :-)

hurting
Regular Member


Date Joined Jun 2008
Total Posts : 59
   Posted 7/8/2008 7:05 PM (GMT -7)   
tom---
if you're still reading, please look up and visit kadian.com.  they offer copay assistance up to $50/month if you are out of pocket for your copay.  i registered online and had my card REALLY quickly; like within a week.  every little bit helps!
-k

Pamela Neckpain
Veteran Member


Date Joined May 2008
Total Posts : 1821
   Posted 7/9/2008 1:53 AM (GMT -7)   
What I know: A new pain doctor didn't really think anything was wrong with me. He decided to take me off Oxycontin. He went fast ... I got sick. I had Avinza, but it didn't work.
I went to new pain management and they started me on Methadone and after about a week that started to work.

Now My Worry: Methadone scares surgeons. They don't know how much anesthesia to give you for tooth problems or appendicitis. My pain doctor told me that if I were to have a surgery, I would need to have an anesthesiologist
present. I can just see an anestheolgist standing there telling my dentist how much and what kind of pain medication I would need for a root canal. It would cost a fortune and Blue Cross wouldn't pay.

So I want to warn you all about Methadone.

I'm all disjointed in this post .... Bottom line, if you are going through withdrawels and are in agony, you need to go to the emergency room. There is the place you can report your horrid doctor.

Pamela Neckpain

Lindaloo
Veteran Member


Date Joined Sep 2006
Total Posts : 1713
   Posted 7/9/2008 5:25 AM (GMT -7)   
To Tom in Pain,

Welcome to the forum. Keep posting. We are here for you too.

Lindaloo
Moderator Chronic Pain
 
Believe in yourself.  Be kind to fellow humans and animals.  Take time to smell the flowers and the coffee.
And by all means, when you are down, ask me for help.  I will be there.
 
Linda


davisgwar
New Member


Date Joined Aug 2010
Total Posts : 2
   Posted 8/25/2010 5:04 PM (GMT -7)   
One note: kadian can be taken once a day or twice on lower doses. Avinza is marketed as a once a day drug with the added benefit that its 10% of its contents release immediately for quick relief. That said; I have been on different opioid pain meds. I'm on Kadian now and it works best for me. 100mg once a day with oxi ir for bp. There is now a sustained release of hydromorphone available now if you have tried dilaudid and it works for you. Also if morphine works for you and you are afraid of abuse you can try Embeda which is like Kadian but also contains narloxone (spelling) which if crushed makes the opiate not work. Kind of like how Suboxone works for addicts. Opana is another option which is sustained release oxymorphone, a potent synthetic opioid previously only available
In a short acting formula. Its marketed as a twice a day dose. For me and a few other people I know it only lasted 8 hrs at the most and had to have 3 sometimes 4 doses a day. I didn't care for it. Also, if morphine makes u itch you are probably better of with a synthetic opiate like oxycontin, opana, dilaudid etc. If anyone has any questions E mail me at: davisgwar@msn.com. I've done a lot of research on pain meds and chronic pain.

Mrs. Dani
Veteran Member


Date Joined Jun 2009
Total Posts : 2787
   Posted 8/25/2010 8:18 PM (GMT -7)   

 

  Dear Davis,

     This topic was started in 2008. I would like to encourage you to start your own "introduction" so that we can give you a proper welcome!

  :-)
 dani


 
TWO roads diverged in a yellow wood
And sorry I could not travel both
And be one traveler, long I stood
 
Chronic Pain Moderator

spinal soldier
Veteran Member


Date Joined Dec 2009
Total Posts : 687
   Posted 8/26/2010 2:44 PM (GMT -7)   
hello Lynn, i think you made the right choice by avinza, as davisgwar noted avinza has a portion of immediate release beads while kadian has not instant effect although it is a steady blood state drug. most extended release are not truley level in the blood; oxycontin, ms contin, avinza, and any generic ms ER are not level. kadian, oramorph, opana, and i think the new exalgo [hydromorphone ER] and embeda are true steady basal rate drugs. avinza levels out but you do get a initial spike. as far as taking a step up in potency of opioids, the oxycodone is apprx. twice as strong as morphine until you climb up the doses latter to around 300mg and then morphine starts to catch up. neither have a ceiling. ther are many cases when people report opioid induced hyperalgesia with oxycodone meaning more sensitivity to stimuli. i think tolerance occurs faster with oxy than morphine in most a its believe in some studies oxy has a high affinity with the kappa opiod receptor where morphine the mu-receptor but in high doses morphine interacts with all the opioid receptors mu, kappa, delta, and sigma. good luck with the avinza
L4,L5,S1 bilateral Laminectomies, Foraminotomies 2002
L4-S1 PLIF with instumentation 2008

current Rx: MScontin 100mgs 2x, dilaudid 8mgs 4x p.r.n., soma 3x, vistaril 25mg 3x prn, wellbutrin 150mg 2x(ADHD),Adderall 20mgs 2x(ADHD)
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