Any input on methadone and roxicodone combo

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bubsykitty
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Date Joined Jul 2008
Total Posts : 23
   Posted 7/12/2008 2:24 PM (GMT -7)   
 
So I met with my new PM Dr yesterday and he advised a new combo of meds for me - 30 mg Roxicodone three times per day and 10 mg of methadone 3 x per day.
Anyone else been on that type of combo??  I am a bit nervous about the methadone cause of the stigma over that drug, but I do trust his advice.  The way he explained it seemed to make a lot of sense to me.  He told me to take the roxicodone first, which is quick acting and short acting, then to take the methadone about an hour later, and repeat 3 x / day.  He explained how the methadone is long lasting and will keep a good level of pain relief and the roxicodone works much quicker, but produces a lot more highs and lows of med level and pain relief.  I was previously on just the roxicodone by itself and found that it worked very well, but it did give me a lot of ups and downs. 
I am hoping that this new combo does what he says it should!! 
Any idea how many days until I get to a steady state to be able to tell if this is a good choice for me or not??  (I forgot to ask him)
 
 
 

razzle51
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Date Joined Jan 2005
Total Posts : 762
   Posted 7/14/2008 11:28 AM (GMT -7)   
what is Roxicodone
well never mind I will look it up.
Syringomyelia T4-T10
Chiari Malformation
Decompression Surgery 1999
 
"Remember That Life Is Short!!!" Life is short, break the rules, Forgive quickly, Love truly, laugh uncontrolably, And never regret anything that made you smile. <!-- / sig -->
 

 
 
 



razzle51
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Date Joined Jan 2005
Total Posts : 762
   Posted 7/14/2008 11:29 AM (GMT -7)   

you need to read this article . I would not combine the 2 at all

http://www.medications.com/drugs/roxicodone


Syringomyelia T4-T10
Chiari Malformation
Decompression Surgery 1999
 
"Remember That Life Is Short!!!" Life is short, break the rules, Forgive quickly, Love truly, laugh uncontrolably, And never regret anything that made you smile. <!-- / sig -->
 

 
 
 



tom inpain
Regular Member


Date Joined Jul 2008
Total Posts : 239
   Posted 7/14/2008 1:32 PM (GMT -7)   
I agree with Razzle. This seems to be a really bad option/ combination. Tom

bubsykitty
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Date Joined Jul 2008
Total Posts : 23
   Posted 7/14/2008 1:57 PM (GMT -7)   
Why do you say it is a bad combo??

The methadone is a long acting med and the oxycodone is short acting and kicks in faster. The way my Dr explained it to me was that it was similar to those that are on OxyContin as the long-acting med with oxycodone IR for BT pain - but it is MUCH cheaper!!

Question for those that are on methadone for pain .... what do you use for BT ??

Disce Pati
Regular Member


Date Joined Apr 2008
Total Posts : 61
   Posted 7/14/2008 11:52 PM (GMT -7)   
I take methadone - 10mg a day for 24 hour coverage (2-5mg pills every 12 hours) and 30 mg Oxycodone a day (6-5mg pills PRN). Basically this is the combination that you described (but different dosages) that your doctor is suggesting to you (roxicodone is a the same as percocet I think - oxycodone plus tylenol; the oxycodone I take is the immediate release without the tylenol component to limit the liver toxicity seen with long term exposure to tylenol).

In my experience, the combination that your doctor is prescribing for you is very common and can be very effective for pain management. I do not think that it is considered a dangerous combination per se, as long as it is taken under a doctor's supervision and you let him / her know of any concerning side effects - just as you would when taking any other prescription medication.

The way your PM doc explained the relationship between the two drug is basically what my PM doc told me and in my case, it seems to work that way; except that the methadone seems to "wear-off" at about 8 hours rather than the 12 (which I was told is common for some people - but that there is a huge variation in how each person metabolizes methadone so that some people will feel it wear off in 6 hours and others may not notice it for 12 or more hours). I have used this combination for 4 years now (the prior 4 years was just IR oxycodone) and I truly believe it has given me a relatively normal life again - I have never run across any stigma attitude about it either (although I haven't had to explain it to any health care person other than my prescribing doctors).

My personal opinion is that it is worth a try to find out if it can help you. It seems to be a reasonable option and if supervised by a knowledgeable doctor you should be in no danger while you give it a try.

Pamela Neckpain
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Date Joined May 2008
Total Posts : 1821
   Posted 7/15/2008 4:15 AM (GMT -7)   
Bubsy,
I take Methadone. It's not perfect but it gets me through the night.
Doctors sometimes prescribe unusual combinations. PDR would scream, but in their practice they've found it's ok. If you're too nervous, change doctor. SEE WHAT THEY SAY.
...NOT
Pamela Neckpain
MEDICAL INFORMATION
HYPERTENSION, SCOLIOSIS, ARTHRITIS, SPONDYLOSIS,
SPINAL STENOSIS THROUGHOUT THE SPINE,PINCHED NERVES C5-C7, NEUROPATHY THROUGHOUT THE SPINE, ANXIETY DISORDER, DEPRESSION, CONSTIPATION, POSSIBLE KIDNEY STONES (OR CANCER) DEGENERATIVE DISC DISEASE C3-C7

MEDICATION
MONOPRIL, HYDROCHLOROTHIAZIDE, METHADONE 10 MG. 3 BY MOUTH 3 TIMES DAILY. XANAX 1 1/2 MG. 3 TIMES DAILY, NEURONTIN 600 MG, 4 TIMES DAILY, FOLBEE TABS, SENOKOT S , 5 TABS AT NIGHT.


tom inpain
Regular Member


Date Joined Jul 2008
Total Posts : 239
   Posted 7/15/2008 7:23 AM (GMT -7)   
When I was on Methadone I never got any relief regardless of dosage. When i asked for a BT meds I was advised that they would rather increase the time frame or increase the dosage rather than mix Methadone with a BT med. My understanding is there is increased Depression when mixing Methadone with
BT. Everyone is different with weight, physical and mental problems and I believe this is all taken in by the Pain Specialist when prescribing.
Another thing I do not miss about Methadone was the stigma attached to it ! When at the Pharmacy they would look at You like You were a junkie especially since I was on really high dosage and also "everybody" wants to know what Your taking and when You state Methadone the reaction is poor and You have to explain how Methadone works. Now Iam on Kadian and no one knows what it is so no explaining to healthy people how and why it is used. Tom

Pamela Neckpain
Veteran Member


Date Joined May 2008
Total Posts : 1821
   Posted 7/15/2008 10:00 AM (GMT -7)   
Tom ...
I can't read ALL the posts. What's BT?
When you speak of "Depression" do you mean emotional or physical ... as in breathing.
Don't ever tell anyone what you're taking. They may like it too much and when they visit you they may pluck some pills from your medicine cabinet.
I live in CA. Not many people think I'm a junkie. I'll bet this is different in different states.
I fear Methadone because I don't believe it will help in immediate pain such as a
sliced hand, broken leg, or Migrain headache. Doctors don't seem to know much about it.
Pamela Neckpain
MEDICAL INFORMATION
HYPERTENSION, SCOLIOSIS, ARTHRITIS, SPONDYLOSIS,
SPINAL STENOSIS THROUGHOUT THE SPINE,PINCHED NERVES C5-C7, NEUROPATHY THROUGHOUT THE SPINE, ANXIETY DISORDER, DEPRESSION, CONSTIPATION, POSSIBLE KIDNEY STONES (OR CANCER) DEGENERATIVE DISC DISEASE C3-C7

MEDICATION
MONOPRIL, HYDROCHLOROTHIAZIDE, METHADONE 10 MG. 3 BY MOUTH 3 TIMES DAILY. XANAX 1 1/2 MG. 3 TIMES DAILY, NEURONTIN 600 MG, 4 TIMES DAILY, FOLBEE TABS, SENOKOT S , 5 TABS AT NIGHT.


tom inpain
Regular Member


Date Joined Jul 2008
Total Posts : 239
   Posted 7/15/2008 8:43 PM (GMT -7)   
Pam: Sorry "BT" was to mean break-tru meds. Methadone for me was a nightmare as I got no relief and weeks went by before they changed to Kadian which helps. The depression I was writing about was mental depression. All of us in pain suffer from Depression i don;t care how strong a person is facing life in pain is awful and some days I can eat the pain like candy and others I simply just want to withdraw from everyone and everything and cry. Drugs that can ad to Depression i try to stay away from. Again this is what " my doctors" told me about pain meds and depression. Sorry if i caused any confusion.
Tom Lasko


Pete trips again!
Veteran Member


Date Joined Nov 2006
Total Posts : 1899
   Posted 7/16/2008 3:53 PM (GMT -7)   
Hello all,
I haven't posted here for a while but I browse alot to see whats going on w/ my fellow CP'ers. Bub, I've been taking this combo for years after trying lots of different meds either alone or together and for me it is by far the best control for my pain. When I took oxycodone alone in different forms and doses it gave me that dopie spacy feeling which was extremly hard to do my work and make it through the 10+hr day with all the ups & downs. With 10mg of methadone in the morning I can work fine w/o feeling like a zombie untill the pain starts to build. As soon as I know it's coming on bad (I never really get rid of all of it) I take a 10mg Roxie which goes staight for the pain and "nips it in the bud" and it seems to be a low enough dose that does not get me stupid. I will end up taking 2 - 4 of the 10mg Roxies during the day depending on how it's going and then take a 10mg methadone at bedtime which kind of gets me through the night. But as someone stated earlier, EVERYONE IS DIFFERENT!!! so what works for me may not work for you. I do get those looks at the pharmacy when the person behind the counter asks what I'm picking up, I know some of those counter make beleive wantobe pharmisists love to do that to you, especially when there is a long line! The M-word always gets attention and those "looks" but at my age I just don't care anymore!! Let them think what they want! The only thing that really scares me is all the kids especially here in Florida who are dying from methadone. I'm afraid they are going to stop prescribing it just like the did with Oxycottin a few years ago. Then it will be back to the drawing board. I hope I don't sound cold, of course it gets me every time a kid dies from an overdose, my son overdosed twice and only God knows why he lived both times. Good news, he is all cleaned up and has been in the Navy for 3 of a 6 year enlistment on an aircraft carrier in the Pacific. Anyway, thats my 2 cents for whatever its worth. I hope everyone has a pain free night tonight and figures out the best treatment for themselves soon!
Your old friend,
Pete
55 years old, Surgury, Radical Prostatectomy 8/20/03, PSA 6.6, Gleason 3 + 3 = 6, Adenocarcinoma extent (moderate) Stage & Margin:T2NOMX, No Metastases, Organ Confined, bone scan: Neg. 3 1/2 years of depression after surgery prior to Hypogonadizm DX, Testosterone Theropy (Testim Gel)since 12/06 but switched to a higher dose of (Androgel) 6/08. Fighting to stay upbeat daily. I am's what I am's and that's all that I am's! (Popeye)  55 and still alive!!! Feel free to pray for me, I can use all the help I can get!!!


bubsykitty
Regular Member


Date Joined Jul 2008
Total Posts : 23
   Posted 7/17/2008 8:39 AM (GMT -7)   
Pete,

I know exactly what you mean about the "wanna be pharmacits" giving THAT look when picking up Rx for methadone!! I felt kinda uncomfortable myself at the pharmacy, but I will certainly not let that get to me.
So far, I am finding this new combo of meds to be working out great for me!! It has only been a week and I can already tell that this is a combo that just might be a keeper for me!!!
Do you live in Florida Pete??? I am in South Florida myself. Just wondering ....


Thank you to everyone that commented above!! I sincerely appreciate all of the input!!!

Happy Thursday !!!!!!!!!!!!!! Can't wait till Friday !!!!!!!!!!!!!!!!!!

Pete trips again!
Veteran Member


Date Joined Nov 2006
Total Posts : 1899
   Posted 7/17/2008 11:17 AM (GMT -7)   

Bubsy,

Yes I do live in paridise~hell depending how you look at it. I live in Central Palm Bch. County but work in Pompano Bch. I just love that 95 commute every day. Fact> US95 in Palm Beach & Broward Counties is the most deadly road in the Nation! I guess its the combo of drivers from all over the nation added to all the islanders, South & Central Americans and lets not forget the "Blueheads" and young "Fast & Furious" kids in their little zoom cars racing around the tractor trailers!!! Hope I don't offend anyone!!

Your friend,

Pete

PS>Sorry about all the PC jibberish on the bottom of my page, my main Forum here at HW is Prostate Cancer. 


55 years old, Surgury, Radical Prostatectomy 8/20/03, PSA 6.6, Gleason 3 + 3 = 6, Adenocarcinoma extent (moderate) Stage & Margin:T2NOMX, No Metastases, Organ Confined, bone scan: Neg. 3 1/2 years of depression after surgery prior to Hypogonadizm DX, Testosterone Theropy (Testim Gel)since 12/06 but switched to a higher dose of (Androgel) 6/08. Fighting to stay upbeat daily. I am's what I am's and that's all that I am's! (Popeye)  55 and still alive!!! Feel free to pray for me, I can use all the help I can get!!!


bubsykitty
Regular Member


Date Joined Jul 2008
Total Posts : 23
   Posted 7/17/2008 11:25 AM (GMT -7)   
Wow - what a small world!!! I live in Western Palm Beach County and used to work in Pompano!!!! My drive was aprx 50 miles each way! Did that drive for about 8 years. But I took the T-Pike, which is not NEAR as bad as I-95. 95 is just plain CRAZY!!!!
BTW, I call them the Blue Hairs!! LOL
Oh yea, little zoom cars is right on!! With the big 5 inch muffler off the back making that obnoxious sound!!!
I better not even get myself started or I'll be having road rage sitting at my desk ....
:-)

Pete trips again!
Veteran Member


Date Joined Nov 2006
Total Posts : 1899
   Posted 7/17/2008 11:35 AM (GMT -7)   
Bubsy,
Sounds like you know EXACTLY what I'm talking about! Sorry to all the others for being off topic.
Pete
55 years old, Surgury, Radical Prostatectomy 8/20/03, PSA 6.6, Gleason 3 + 3 = 6, Adenocarcinoma extent (moderate) Stage & Margin:T2NOMX, No Metastases, Organ Confined, bone scan: Neg. 3 1/2 years of depression after surgery prior to Hypogonadizm DX, Testosterone Theropy (Testim Gel)since 12/06 but switched to a higher dose of (Androgel) 6/08. Fighting to stay upbeat daily. I am's what I am's and that's all that I am's! (Popeye)  55 and still alive!!! Feel free to pray for me, I can use all the help I can get!!!


happydaysagain
New Member


Date Joined Jul 2008
Total Posts : 4
   Posted 7/19/2008 2:23 PM (GMT -7)   
hello is there anyone that can give me some information abount a 5 day cold turkey withdrawl from Roxicodone. my husband is not doing as well as he thought he has been on it for 4 years and needs to stop he was taking 240 mg a day
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