Cymbalta good for my nerve pain

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MaryMary
New Member


Date Joined Jul 2008
Total Posts : 10
   Posted 2/2/2009 3:47 AM (GMT -6)   
It is just over a week since I started Cymbalta 30mg and the side effects have been difficult (nausea and difficulty sleeping) but have already passed. I have been taking Gabapentin for a year - it helped the nerve pain but I still had a build-up as the day went on, and had a lot of pain from the middle of the day onwards. Since starting the Cymbalta as well as the Gabapentin I am almost pain-free all day. Bliss - long may it continue. I feel like a normal person again for the first time in a year and a half, since the operation that gave me the nerve damage in the first place.
Mary

Lindaloo
Veteran Member


Date Joined Sep 2006
Total Posts : 1711
   Posted 2/2/2009 10:39 AM (GMT -6)   
Mary,

That's wonderful news!! I hope it continues for you as well. Just curious, are you taking the gabapentin just once a day?? I only ask because you were saying you had a build up of pain and I know with the Lyrica (close to gabapentin) you need to spread it out during the day to attain maximum pain relief.

But maybe that is all behind you now that the cymbalta is working so well for you. My husband was on cymbalta and did real well, at first, but after a while he developed severe nausea and had to stop the drug altogether.

Anyway, I am happy you posted your wonderful news. Let us know how you are doing in the coming weeks. Check in and give us an update, won't you??

Lindaloo
Moderator Chronic Pain
 
Believe in yourself.  Be kind to fellow humans and animals.  Take time to smell the flowers and the coffee.
And by all means, when you are down, ask me for help.  I will be there.
 
Linda


MaryMary
New Member


Date Joined Jul 2008
Total Posts : 10
   Posted 2/2/2009 11:14 AM (GMT -6)   
I take 300 mg Gabapentin at bedtime and 200 mg at lunchtime. Also now 30mg Cymbalta at bedtime. Maybe more Gabapentin through the day might have helped - I know that the doctor and I were trying to avoid more drowsiness during the day and that's why the daytime medication is low. I'll stick with what I'm doing for now as it's working at the moment. I'm a bit concerned though that I have read there can be interactions with anti-convulsants - does this mean I shouldn't be taking both Cymbalta and Gabapentin?

PAlady
Veteran Member


Date Joined Nov 2007
Total Posts : 6795
   Posted 2/2/2009 12:42 PM (GMT -6)   
Mary,
As far as I know taking both of those is fine, although I'm not a doctor. Cymbalta is an anti-depressant, not an anti-convulsant. And you're still on the lower dose of cymbalta, so even if it stops working you've got room to move up.

Great news!

PaLady

Lindaloo
Veteran Member


Date Joined Sep 2006
Total Posts : 1711
   Posted 2/2/2009 3:14 PM (GMT -6)   
Gabapentin is an anti-seizure medication. Just to let you know, PaLady.

Lindaloo
Moderator Chronic Pain
 
Believe in yourself.  Be kind to fellow humans and animals.  Take time to smell the flowers and the coffee.
And by all means, when you are down, ask me for help.  I will be there.
 
Linda


PAlady
Veteran Member


Date Joined Nov 2007
Total Posts : 6795
   Posted 2/2/2009 8:49 PM (GMT -6)   
Yes, LInda, I do know that. But I thought Mary was thinking cymbalta was, also. I take gabapentin. My neurologist also has told me it's a very weak anti-convulsant, and rarely used for seizure disorders. Mostly it's used for us CPer's with nerve pain, and even for some mood disorders. Oh, these drugs!!

I think I might have read Mary's post wrong. But I've never heard of a problem taking cymbalta with neurontin (meaning an anti-depressant & an anti-epileptic drug aren't incompatible, although there can be drug interactions for some folks). I've seen these drugs combined quite frequently.

Post Edited (PAlady) : 2/2/2009 6:54:16 PM (GMT-7)


deb in indiana
Regular Member


Date Joined Aug 2005
Total Posts : 387
   Posted 2/2/2009 9:07 PM (GMT -6)   
I take them both 60 mg cymbalta 400 of gabapentin i just started these together a few months ago .The pain down my leg to my toes finally went away after several years with the two toghter and now i sleep so good that pain would wake me up at night all the time Take care Deb

MaryMary
New Member


Date Joined Jul 2008
Total Posts : 10
   Posted 2/3/2009 3:37 AM (GMT -6)   
Thank you ladies. This is very reassuring. I am so pleased at the moment to have my lowest pain levels for a very long time. I was getting very depressed that it was getting worse and now its almost gone. Good to know that Gabapentin and Cymbalta should be OK together.

PAlady
Veteran Member


Date Joined Nov 2007
Total Posts : 6795
   Posted 2/3/2009 3:36 PM (GMT -6)   
Mary,
And it GREAT for us to hear a success story! So I'm so glad you posted. And remember just in case some of your pain should come back you're still on a low dose of both of those drugs (I'm not a doctor, just used to takiing/or have taken them, so have researched their websites!).

Again, great news, and feel free to keep posting if you want.

PaLady

s.pajuelo
New Member


Date Joined Mar 2009
Total Posts : 1
   Posted 3/14/2009 2:38 AM (GMT -6)   
Hi, I'm new to Cymbalta, and have been prescribed to it for chronic pain in my feet and back that has persisted for over a year, due to a "chemical imbalance" the doctor states. So
I guess I am more sensitive to pain. But anyway i was wondering how long I would need to take this medication to resolve the pain, or if it is something that i have to live with, and take as treatment in pain management?

MaryMary
New Member


Date Joined Jul 2008
Total Posts : 10
   Posted 3/14/2009 4:58 AM (GMT -6)   
For me, I noticed a big reduction in pain within 2-3 days of starting Cymbalta. My depression lifted very quickly too - not surprising really if I consider that the depression was only because of the pain and the loss of hope that I felt at that time. The initial side effects of Cymbalta, though very difficult, did not last long and were well worth working through. I have stopped taking my Gabapentin at lunchtime and the pain is no worse than when I was taking it. The benefit is, of course, that I am very much more alert in the afternoon and don't fall asleep quite so early in the evening. I still take the Gabapentin at night with the Cymbalta.
My doctor told me at the outset that I should stay on Cymbalta for at least 6 months. It was prescribed mainly for my depression, without any real expectation of pain relief so I don't know what will happen now if I have to stop taking it. Of course, I'd be worried that the pain will increase again. But, I'll cross that bridge when (and if) I come to it.


Mary

Chartreux
Veteran Member


Date Joined Aug 2006
Total Posts : 8030
   Posted 3/14/2009 10:38 AM (GMT -6)   
Mary, I'm glad your getting relief from your pain and sure
Hope that it continues for you and will keep my finger's crossed for you..
I tried Cymbalta but it gave me night sweats so bad it would keep me up,
so I had to stop using it..
To s.pajuelo, you might want to consider going to a Pain Management Clinic
since you've been in pain for over a year, Cymbalta works good with other
medications and maybe it's time for you to seek out better pain control...
Hugz to both Mary and s.pajuelo...
{{{{{{{{{{{{{{{{{{{{{{{{{{{{{{{HUGZ}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}
**********************************************
* Asthma, Allergies, Osteoarthritis, Spinal Stenosis, Degenative Disc, Fibromyalgia, Gerd, Enlarged Pituitary Gland
******** "We could never learn to be brave and patient if there were only joy in the world" from Helen Keller *********

********>^..^<********>^..^<********>^..^<********


Tony McGuire
Regular Member


Date Joined Feb 2009
Total Posts : 483
   Posted 3/14/2009 10:06 PM (GMT -6)   
I've been through several of the medications mentioned here. Gabapentin (sp?), neurontin, and amatriptalyn were all nearly useless as was Fentanyl. I got results from amatriptalyn, but it was like drinking beer all day and night while taking that one. My 'issue' is chronic pain from Diabetic Neuropathy. I've seen a General Practitioner, Podiatrist, 2 neurologists, and a pain management specialist. They ALL tell me there is nothing for me but pain management at this point; the only benefit I can hope for is to control the pain.

The magic combo for me is Lyrica 150mg 3xDay and Cymbalta 60mg 2xDay.

I do take other medications, but the above combo breaks the pain chain so the other stuff has a chance to do at least some good against the pain.

If I change things at this point, I either have brain function issues or excruciating pain so it appears I've found about the best offset location for me and meds.

The answer to the original poster is that Cymbalta and Lyrica CAN be a wonderful combination. And yet I've discussed this with others who say the combo isn't anything for them. So, once again it is all individual.

Best of luck finding your best combination(s). I hope you can find 100% relief.
Wife: Liz
Dogs: Koshka & Chomp


bluejet2
Regular Member


Date Joined Feb 2009
Total Posts : 487
   Posted 3/15/2009 12:49 AM (GMT -6)   

It is so nice to hear that people getting varying degrees of relief from their CP, it gives me a little bit of hope.  I have been on a lot of the meds spoken of, but not in the same combinations, and either because of persistent side effects or no relief, I have stopped taking them.  Presently I have an intrathecal pump which delivers dilaudid and bupbivicaine directly into my spine, and in addition I take 60 mg Roxicode every 3 hours, 20 mg flexiril 3 x's a day, 1 mg Klonipin a.m. & p.m., and 20 mg Ambien at bedtime and I have a spinal cord stimulator that I have running at its highest settings 24/7 (I go through a battery that is supposed to last 5 - 7 years in as little as 2 months), and with all that, my pain level is rarely below an "8", usually a "9", and often reaches a "10" and if after trying a hot shower, laying on a heating pad, and a light back rub if I can find willing hands, I will go to the emergency room where I usually encounter nasty attitudes from doctors, and nurses telling me that they have never seen someone on the level of meds I'm on, and after hours of torture laying on an uncomfortable gurny, getting 2 mg of dilaudid at a time, I get admitted every time for several days of dilaudid by IV in addition to my regular meds until the pain gets back "under control" at an "8" or "9" on the pain scale.

I am grateful for their willingness to help me at all in the ER, because I know many CP sufferers are turned away completely because they are suspected of being drug seekers, and as wrong as that is, I understand the doctor's and nurses point of view as well because I have an identical twin who has been abusing prescription pain meds for years and has been turned away many times.  But it seems to me that these doctor's & nurses because of their experience be able to "read" people better and be able to weed out the addicts from the real sufferers.

Take care all, and enjoy your alleviation from the horrors of CP. 

 

Bluejet2

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

  

 

 

 

 

 

 


imgettingwell
New Member


Date Joined Mar 2011
Total Posts : 1
   Posted 3/9/2011 8:47 AM (GMT -6)   
Message to MaryMary: you stated in one of your posts this statement: "The initial side effects of Cymbalta, though very difficult, did not last long and were well worth working through". When you said that your effects were very difficult, what do you mean by very difficult? What did you expeirence? What did you do to "work through it"?
I'am starting Cymbalta today, also taking Gabapentin. Yes I did read all about Cymbalta. But would like to get some answers from someone who suffers exactly from what I'am suffering from as well. Please help. I know it has been a long time since you posted anything, but if you are still out there, please help me. rolleyes
 
Sincerely,
imgettingwell

Jim1969
Veteran Member


Date Joined Jul 2009
Total Posts : 2042
   Posted 3/9/2011 9:36 AM (GMT -6)   
It is not uncommon for people just starting out on Cymbalta to experience "flu like" symptoms to one degree or another. Upset stomach, feeling kind of "disconnected", runny nose, etc are all quite common. For some people the initial side effects can be quite bothersome and for others very tolerable.

The majority of people who do experience side effects usually start to notice them lessening by the end of the first week and completely gone within 2-4 weeks. If after the first week your symptoms become worse contact your doctor and if they have not started going away within 2-3 weeks also contact your doctor.

The "bad" news with Cymbalta is that you may not feel any pain relief at the 30 mg dose. Some do, some feel a little relief and some do not feel any and need to have a dose increase to 60 and maybe even a second one to 90 mg before they will know if they are going to get any relief from this medication. The good news is that it is fairly unusual for any of the side effects to return with each dose increase. Also there should be around a 1 month period in between any dose increases at the minimum. Cymbalta is a "cumulative" type medication meaning the longer you take it the better it will work.

If you and your doctor decide it is not working and you need to stop taking it DO NOT go cold turkey. This medication needs to be stepped down slowly or you may experience some rather bad side effects.

Like any medication your experience with it may differ from anyone elses. Some find great success with it, some find none at all and others varying degrees, but it's overall track record is good enough to make it worth a try. A lot of how well it works seems dependent on exactly what type of pain you are having and the cause of it. It seems most effective for pain associated with fibro, nueropathies, and depression. It does not usually work so well for pain due to things like herniated discs.
2 confirmed herniated lumbar discs. Spinal Arthritis. Spinal Stenosis, diabetic peripheral nueropathy.

CRPSpatient
Forum Moderator


Date Joined Mar 2011
Total Posts : 1139
   Posted 3/9/2011 9:22 PM (GMT -6)   
I'm glad that some people have had relief with Cymbalta - for me it was an absolute disaster and nearly cost me my life. I was put on it by a pain psychiatrist on our very first meeting - partly for my CP, partly for my depression. I knew when I started it that there was a possibility - as with all antidepressants - that it would make my depression more severe at first - but I went straight into a major depressive, almost psychotic episode. I had no connection with reality - no idea who I was, where I was, what was going on - just that the whole world was against me and was out to get me. I'm just 'lucky' that I was so disconnected that I couldn't figure out how to open the blister packs on my meds, or reach a knife, or anything else to harm myself - because all I wanted to do was kill myself.

grainofsalt
Regular Member


Date Joined Aug 2010
Total Posts : 215
   Posted 3/13/2011 9:31 AM (GMT -6)   
Mary,

I'm glad to hear the Cymbalta worked well for you. I do think anti depressant style therapy can be very effective. It kind of makes sense when you consider that in some people there is a link between pain and depression. Now I think most people that suffer from chronic pain do not get the bulk of their pain from depression. However, I do think depression can make it worse and treating depression in people with neuro pain allows the body to better deal with the original source of pain.

I think everyone is different and that different pain types require different treatment. For me personally, I use Nycynta which has a partial anti depressant effect (NRI effects) and opioid Mu agonist effects. Nycynta binds weakly to Mu receptors (stronger than tramadol, weaker than hydrocodone) but yet its been shown in people with nuero pain to sometimes be as effective as percocet. The benefit is a less sedating narcotic that builds up tolerance slower.

I am glad to hear your story though because it tells me reassures me that the anti depressant effects of my medication are playing a considerable role. :)
MRI revealed disc bulge and test injections revealed RA. Radio Freq procedures have decreased the severity of pain by about 1/3rd. currently on 75 mgs of Nucynta (tapentadol) 3 time per day. Works as well as 10 mgs of hydrocodone, less addictive, no tylenol, but schedule II. Also take Alieve OFTEN, much better than Ibu.
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