Good results with Cymbalta

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BrentE1961
Regular Member


Date Joined Jan 2009
Total Posts : 47
   Posted 3/2/2009 12:04 PM (GMT -6)   
My PM doc recently started me on Cymbalta. I took 30mg a day for two weeks and then 60mg a day. It took a couple of weeks for the medicine to kick in. It has really helped with the pain in an odd way - it didn't get rid of the pain, but it made it more "dull". It used to be a very sharp pain that was impossible to ignore or tolerate. Now it is more of an "ache", albeit a pretty strong one that never quite goes away. Has anyone else had an experience like that?
47 YO Male, chronic back pain. Herniated disc L5/S1 2003. Discectomy with partial laminectomy 2004. Now told I have Failed Back Syndrome with discogenic pain.


Pain level varies from disturbing to nearly intolerable.


Stella Marie
Veteran Member


Date Joined May 2005
Total Posts : 601
   Posted 3/3/2009 5:38 AM (GMT -6)   
I am also on Cymbalta and I had a noticeable reduction in may pain when I was titrated up to 60 mg per day. Even though Cymbalta is considered an antidepressant, it definitely is a keeper for me when it comes to non-opioid choices for pain relief.

I am glad to hear that it worked well for you too.

Stella Marie

Rare neurodegenerative disease called “Multiple System Atrophy”.  Wheelchair, O2, & Bipap, intrathecal pump, Neurostimulator, dystonia, neuropathic pain and spasticity.


Tony McGuire
Regular Member


Date Joined Feb 2009
Total Posts : 483
   Posted 3/3/2009 9:18 AM (GMT -6)   
I take 120mg Cymbalta, 60mg x 2, but it only works for me when in combination with Lyrica.
Wife: Liz
Dogs: Koshka & Chomp
Brain Zaps: Gabitril
Kidney: Simvastatin
Diabetes: Metformin, Insulin
Pain: Morphine IR, Methadone, Cymbalta, Lyrica


BrentE1961
Regular Member


Date Joined Jan 2009
Total Posts : 47
   Posted 3/3/2009 10:22 AM (GMT -6)   
Stella, Tony, thanks for the replys. Did either of you experience what I did where the nature of the sensation changed more than the intensity of it? For me changing from a sharp pain to a dull ache sensation makes it a lot more tolerable, even if the sensation is still pretty strong. I haven't had a medicine do that before - usually the nature of the sensation stays the same while the intensity decreases - that is to say a hot, sharp pain stays a hot , sharp pain, it is just less intense. The Cymbalta actually changed the way I perceive the pain - hot, sharp to achy pressure.
47 YO Male, chronic back pain. Herniated disc L5/S1 2003. Discectomy with partial laminectomy 2004. Now told I have Failed Back Syndrome with discogenic pain.


Pain level varies from disturbing to nearly intolerable.

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