Elderly, it seems Mallincroft has always turned out inferior meds according to thsoe who take them on a regular basis. That isnt just the Hydro's it runs into the percs and many others.
I recall a study done on methadone versus methadose a few years back before they changed to the little long tabs they now make.
The methadose seemed to cause alot of problems in folks who took them and it was found that not only did they contain only 8.1mgs of actual methadone they were chalked full of simple glucose and talc? Now the problems were that this was not a widely known fact and those folks who were diabetic and borderline hyperglycemic were pushing their glucose to the limits making for more insulin and or floating readings of testing. I often wondered how the methadone tabs could be so different in size back then as methadose was 4 times larger then the brand,that told the story.
The methadose used to cause me severe headaches at the end of the day and it never happened on the methadone. It seemed that the added glucose even though I was not diabetic was enough in higher doses to push me into hyperglycemia in turn causing h/a.
Once they did away with methadose and went to making the little "coffin" like pills I had no problems and the last testing I saw re:the actual chemical components of it were as close as they could get to brand and there is no difference in price between the two.
I imagine somewhere on the internet if you can go indepth enough you will find somewhere someone who has actually done such a test on other meds and there in lies your answers as to how and why it doesnt work the same.
Sometimes it isnt what they actually leave out but more of what they add to it.