Amitriptyline & Cymbalta

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BrokenJen
New Member


Date Joined May 2009
Total Posts : 12
   Posted 5/27/2009 9:46 PM (GMT -7)   
Anyone here on that mix? I had one doctor say it was ok, and another say they have no clue. My research suggests it's not a good idea, but I am still curious about it.

-Jen

Sudden onset of chronic pain nearly 5 years ago.
Diagnosed with increasingly severe DDD, Spondylolysis at L5, many bulging discs from hips to skull and 2 herniated discs.
Current treatment - Oxycontin 30mg/x2 daily. (No BT meds found.) Amitriptyline 100mg/nightly for migraines. Related?
No surgical options to date.
Botox denied by Ontario's workers comp. Up next - Methadone.


Tony McGuire
Regular Member


Date Joined Feb 2009
Total Posts : 483
   Posted 5/27/2009 9:54 PM (GMT -7)   
I took Amitriptyline and it tripped me out. Really.

So I got switched to Cymbalta. My PCP indicated they were both anti-depressants and not suitable to be taken together. But I'm not a doctor so I don't try to give out information on that level.

Both of them enhanced the Lyrica I was taking, though, just as they were supposed to. I just couldn't handle the Amitriptilyne.
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BrokenJen
New Member


Date Joined May 2009
Total Posts : 12
   Posted 5/27/2009 9:59 PM (GMT -7)   
I have been on Amitriptyline for over 5 years for migraine prevention. It does not touch the depression issues I have. I was weaning off of it so I could switch to Cymbalta, but I had a doctor tell me not to. He adviced me to go back to my regular dose, and take the Cymbalta with it. I told him about my research stating that wasn't wise, and he shrugged it off... Every other doctor I have asked about it knows nothing about combining the two. Thus my asking here. :)


-Jen

Sudden onset of chronic pain nearly 5 years ago.
Diagnosed with increasingly severe DDD, Spondylolysis at L5, many bulging discs from hips to skull and 2 herniated discs.
Current treatment - Oxycontin 30mg/x2 daily. (No BT meds found.) Amitriptyline 100mg/nightly for migraines. Related?
No surgical options to date.
Botox denied by Ontario's workers comp. Up next - Methadone.


PAlady
Veteran Member


Date Joined Nov 2007
Total Posts : 6795
   Posted 5/27/2009 10:01 PM (GMT -7)   
Broken Jen,
Is it a pm doctor that's telling you it's ok to take them together, or a psychiatrist? I'd want at least a second opinion from an expereinced psychiatrist with some pain management background. Sometimes doctors combine medications based on their clinical experience (experience with patients), not necessarily what a drug is created for. I'm not sure if these should be taken together, but I'm not sure they coudn't be in certain circumstances.

Well, that' a big help to you, right! (NOT) If you're not sure see if you can get more than one opinion, and do a little research on the medications yourself. See if the manufacturers say anything about contraindications with other medications. You might also ask the opinion of an experienced pharmacist.

Wish I could help more.

PaLady
Sorry Jen - we must have been posting at the same time. Looks like you've already done your research. Have you asked your doctor WHY he thinks it necessary and ok to take them together? What's the benefit for you, and what are the risks? I think you're owed an explanation so you can make an informed choice. Good luck!
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