2 long acting meds

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Regular Member

Date Joined Mar 2007
Total Posts : 161
   Posted 9/19/2009 4:09 PM (GMT -6)   
Hello all!  I hope everyones pain levels are low.  I have a question about long acting meds.  I am on methadone now.  I have been having b/t pain that is bothering me pretty bad.  I let my PM doc know this and she said she does not prescribe b/t meds with methadone but that she does have some patients that have added a second long acting med to the methadone.  She did not elaborate on what kind of long acting.  I was just suprised to find out that this could happen.  Have any of you ever heard of 2 long acting meds for pain taken together?

Veteran Member

Date Joined Jun 2005
Total Posts : 610
   Posted 9/19/2009 9:40 PM (GMT -6)   
A while back, when I Was 19 my doctor had just switched my Oxycontin to the fentanyl patch cause my psychitrist said taking certain anti-deppresants made the Oxycontin not get absorbed right (or something like that) so they wanted me to use the patch cause it got absorbed in the body diffrent, but they kept me Oxycontin still for breakthrough pain, and it worked fine.

But I wouldnt understand why you cant use breakthrough meds on Methadone. I know people who take Methadone with oxycodone and/or hydrocodone for breakthrough. But I guess every doctor is diffrent. Maybe you can look up some medical litature online and see if their's anything about taking breakthrough meds with methadone and take it to your doctor and see if that changes their mind.


Carmen~*~*~Chronic Pain Moderator

DX-Chronic Pain due to two freak car accidents, Pancreatic Divisum,Fibromyalgia, Asthma, Depression w/anxiety, Migraines

Meds- Suboxone 16mg for pain, Cymbalta 60mg, Lyrica 50mg, Imitrex 100mg PRN,Ibprofen 800mg PRN, Ventolin Inhaler PRN, Visteril PRN


Veteran Member

Date Joined Jul 2008
Total Posts : 2268
   Posted 9/19/2009 11:03 PM (GMT -6)   
I would also suggest what exactly "long acting meds" means. Some doctors, I've found, use it to refer to scheduled meds (even if they only last for 4-6 hours) whereas other docs use them to refer to once a day (or once every 2-3 day) meds.

Beyond that, I think it could be worth a try. Best case, imho, is not to have break-through pain in the first place. Perhaps that's your doc's goal? Just a thought. If you try things her way & you're not getting enough relief to function, then maybe you can go in search for another pain doc.

well wishes,

Veteran Member

Date Joined Aug 2008
Total Posts : 3193
   Posted 9/19/2009 11:11 PM (GMT -6)   

Couple of quick thoughts: When I was on Methadone (maybe 3 years ago?).....I had a breakthrough med w/ it. I've been on so much, just about every combo, that I can't remember "which" one right now.... Just from reading other posts here and my own experiences, I think when a doctor says something like "I don't prescribe "xyz" w/ "xyz" (and it's not two meds that can't be combined, or something else) - I believe it has to do w/ the doc and his/her own experiences, viewpoints, etc.

Same thing with combining two long acting meds. When I first started long acting meds (after going through all the short-acting ones)....I was started on a combo of long-acting meds. Looking back, I'm not really sure why! (I'm much more "pro-active" re: my health now...and know why I'm taking certain things, etc...but, in the beginning, I did as I was told!!).... Anyway, I was on a combo of morphine and oxy -- plus a breakthrough med. After a move and going to a new pain clinic - the new doc thought that was way too complicated....and put me on one LA med (w/ a higher dosage) and one BT med.

All of that said, I never took methadone w/ a LA med. To be honest, I can't remember ever seeing anything in all my CP readings about methadone combined w/ a LA med. Hmmmm. But maybe someone else has?

Pain Issues: Neck/back pain; migraines; carpal tunnel syndrome; widespread joint/muscle pain, nerve pain in hands, arms, feet; I also have POTS/dysautonomia; CFS/Fibromyalgia; Severe Hypertension; Hypothyroidism; Addison's Disease; Central Sleep Apnea; etc etc

Meds: MS Contin (480mg daily); Dilaudid (8mg/3x day); Actiq (1200 mcgs/1x per day); Soma (3x day); Atenolol; Midodrine; Phenergan; Effexor and on the list goes...

Future Plans: Intrathecal Pain Pump; already completed trial; awaiting my decision for implantation

Veteran Member

Date Joined Nov 2008
Total Posts : 1037
   Posted 9/20/2009 5:17 PM (GMT -6)   
Hey, I think that Dr.'s may say "long-acting" but really mean something else...so I would ask when you go back...Or maybe even call on Monday...tell thrm that you are having bad BT pain and need something else...

Rhonda aka Me.
I have been a spectator for so long..Now it's time to participate.......
Post Lamenectomy Syndrome, Spinal Stenosis, DDD....
1999 Hemi Lamenectomy/2005 Spinal Fusion(L4-S1)
Methadone 120 mg. a day/  30 mg. Oxycodone as needed(up to 4 x a day)
High Blood Pressure: Lisinopril HCTZ 10 mg. daily
Type 2 Diabetes: (March 16, 2009)
Metformin HCL ER 1000 mg. at night..Glipizide 10mg. 2X in the morning
Lantus 35 units at bedtime with Solostar Pen                                                                   


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