Nucynta VS Percocet

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drjimmy
Regular Member


Date Joined Dec 2008
Total Posts : 110
   Posted 9/30/2011 2:02 AM (GMT -6)   
My Father-In-Law was taking Percocet and it was helping him. His new doctor took him off the percocet, because he feels it's too addictive and that as his body adjusts to it, his dose will have to keep being increased. In it's place he prescribed something called Nucynta...His doctor says it's an Opiod, like Percocet, but less addictive. I researched Nucynta for him and most people seem to get less pain relief from Nucynta vs Percocet. Also many people complain about more side effects from Nucynta. Apparently, both are Schedule II narcotics...Has anyone been on Nucynta? If so can you talk about your experience with it. If you have also been on Percocet, could you please describe your level of pain relief and side effects with the 2 medications? Thank you for any feedback.

Eric
Herniated Lumbar Disks L5 S1, L2 L3
Herniated Cervical Disks C6 C7
Spinal Stenosis
Degenerative Arthritis Left Knee
Pes Planus Both Feet
Multiple Neuropathies
Brachial Plexus/Thoracic Outlet Syndrome
Nerve Pain in Arms, Hands, Back, Legs, Feet, Groin, Testicles

Screaming Eagle
Forum Moderator


Date Joined Sep 2009
Total Posts : 4981
   Posted 9/30/2011 11:45 AM (GMT -6)   
 
       Hello Dr! wink
 
             I did a quick search on the med, and this is what I found for you. I will try to add more in a bit as I do a little more research on it.
 
 
 
       I do have a couple of questions for you. What is wrong with your father inlaw, and how long has he been taking the Percocet? As far as side effect's with the Percocet....the only thing I suffered was constipation. Also the Percocet 7.5 which I am scripted X3 is to be used as BT. For me,...the BT relief only last about 2hrs max, and then it was down hill from there.
 
  At one time I was actually using them on a regular schedule, and was part of my baseline, because my Oxycontin dose was not high enough for my total baseline med. Recently I asked my Dr to try Cymbalta on me, and now I'm actually using the Percocets for BT for the first time in my pain career of 8yrs. I'm a firm believer if you are a long term chronic pain patient, then you should be on a long term ER medication, and use the IR med's for BT as needed. (IMHO)
 
        Hope this helps!
 
        SE wink
Moderator Chronic Pain Forum

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Post Edited (Screaming Eagle) : 9/30/2011 11:12:59 AM (GMT-6)


grainofsalt
Regular Member


Date Joined Aug 2010
Total Posts : 215
   Posted 10/2/2011 1:48 AM (GMT -6)   
Jimmy,

I personally got more pain relief and longer lasting relief from Nucynta than from Percocet-5. However, Nucynta is more specifically geared towards neuro pain so some might benefit greatly from it while others, not so much.

I have sucessfully reduced my pain from a level 8 to a level 0 with Nucynta on a few occasions, however like most medications there are times that substantial pain relief did not come through for me. Again for my pain, I prefer the relief Nucynta gives over percocet and would much rather have it prescribed than percocet for chronic pain relief. I was on it for several months before I noticed any genuine increase in tolerance, so for me it builds tolerance at about 1/2 the speed of percocet. (side note: my trail with hydrocodone after the min invasive surgery failed, the pain level was not reduced enough for vicodin 5 mgs to be effective, so I'm back on the tapentadol with better results).

You should be aware that nucynta IS a real opioid that IMO is stronger in its narcotic activity than hydrocodone and tramadol but weaker than that of morphine and oxycodone. However, what makes nucynta better for nuero pain is its additional norephedrine reuptake inhibitor properties which seem to account for nearly half of its pain relief action. From all the studies I read up on it, its anti depressant effects are more potent than those of tramadol. I can vouche for that from personal experience.

Please only take what I say as personal experience. Please discuss these issues with your doctor and pharmacist. I'm not an expert by any means and even if I have read many studies and have personal postive experience, its a decision you, your father in law, and his doctor should come to in joint agreement. :)

A few words of advice from my personal experience. The 75mgs dose of nucynta seems to be equal to percocet (oxycodone) at the 10 to 15 mg level. Also, this stuff CAN be addictive and I have had my prescription of it stolen before (the person had be secretly taking a tablet here and there while they were living with me and became hooked, said person is no longer living with me thank God). HOWEVER, in my personal opinion this medication is less addictive than oxycodone and hydrocodone. I've discussed the addiction risk with my doctor and they stated that they believe this medication to be of low risk for addiction. Also, please make sure your grandfather remains well hydrated while taking this medication. I can't stress this point enough. This medication can dehydrate you. It can also make you dizzy and have mild distortions if you accidentally take the doses too close together. Also, please watch for symptoms of seratonin syndrome.

Good luck sir, and I hope this helps. I think the medication might work very well for him, but it really depends on the main cause of his pain and how his body accepts the medication. for me its a mericle drug, but a lot of people dislike it.
MRI revealed disc bulge and test injections revealed RA. Radio Freq procedures helped for months, but pain is up and im having the procedure done again. Currently on 75 mgs of Nucynta (tapentadol - A MOR + NRI) 2 to 3 time per day and Soma 350 as needed.

Zap2
Regular Member


Date Joined Oct 2010
Total Posts : 20
   Posted 10/5/2011 1:25 PM (GMT -6)   
My understanding of Nucynta is that it's similar to Tramadol, just stronger. By that I mean it is a norepinephrine reuptake inhibitor as when as an opiod. I used tramadol successful for quite a while, but I know people have mixed feelings about it. Is the Nucynta your father in law is taking extended release or instant release? That could make a large difference. Percocet is instant release, so that change up could be effecting things, probably resulting in longer acting medicine, but it isn't quite as strong.

kathy60
New Member


Date Joined Jul 2012
Total Posts : 1
   Posted 7/1/2012 9:34 AM (GMT -6)   
I have been on percocets which I will call perks my dr said they peak like mountains up and down I take them and nucyunta er I find I take less percocets iam given 5 a day on perks and nucynta perks 10-325 nucytna 200 but the nucytna takes awhile to work maybe 90 mins the nucy has to be time released nucytna ER and it lasts on me about 11 so it has helped me a great deal I have cut down on the perks maybe 2 aday compared to 5 perks I would feel like I was eating perks and still in pain ,so nu to me with perks is working well but I take 200 mg please talk to your dr about all you have told us it takes a few times to find out what works for you I do agree with the other s on this (extended release ) MAKES THE DIFF

fireflyhillary
Regular Member


Date Joined Jan 2012
Total Posts : 148
   Posted 7/4/2012 11:21 AM (GMT -6)   
Hello drjimmy! I have been on Percocet and Nucynta, so I will give you the results that I had...I had been on and off Percocet for almost 10 years due to the many surgeries I have had. When I started taking it for my chronic pain issues I found that the dosage had to be increased several times. After being on the Percocet 10/325 for a while and it not really helping me any longer my pain doctor put me on Nucynta 75. I did that for a couple of weeks and it did help more than the Percocet, but it's relief only lasted 2-3 hours. So, I was put on the extended release 100 to take every twelve hours and the regular 75 to take for breakthrough pain. I have found this to be pretty effective and much more effective than the Percocet. However, my pain has been really bad recently and the Nucynta is barely touching the pain...I see my pain doctor on Monday and will be discussing this with him.

I have not really had any side effects except for the regular Nucynta making me sleepy sometimes. I've also read that there are more side effects with it than with Percocet, but that has not been the case for me.

I hope your father-in-law gets some relief from the Nucynta...Keep us posted.

yeah
Current: Lumbosacral Spondylolysis, Lumbosacral Neuritis, Arthritis L3-S1, Facet Syndrome, SI Joint Dysfunction, Interstitial Cystitis, Vulvodynia, Restless Leg Syndrome, Bi-polar, IBS, Fibromyalgia, PTSD. On too many medication's to list & have had many surgeries & procedures and I'm only 34.

fireflyhillary
Regular Member


Date Joined Jan 2012
Total Posts : 148
   Posted 7/4/2012 11:22 AM (GMT -6)   
Doh! I just realized this is an old post......sorry about that.
Current: Lumbosacral Spondylolysis, Lumbosacral Neuritis, Arthritis L3-S1, Facet Syndrome, SI Joint Dysfunction, Interstitial Cystitis, Vulvodynia, Restless Leg Syndrome, Bi-polar, IBS, Fibromyalgia, PTSD. On too many medication's to list & have had many surgeries & procedures and I'm only 34.

Screaming Eagle
Forum Moderator


Date Joined Sep 2009
Total Posts : 4981
   Posted 7/4/2012 12:27 PM (GMT -6)   
Wake up honey!tongue LOL …we all have made that mistake, and I'm sure it may help someone else anyways! I will go ahead and lock the thread.

Have a great day!

SE wink
Moderator Chronic Pain Forum

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