I have been on 6 mp for a year and a half. At 50 mg I had improvement but I still wasn't in great shape. I have been at 75 mg for 6 months and after a long two years since diagnosis and surgery, my GI declared that I am in remission. I love this drug. I feel well and I would say the only "side effect" I feel is at this dosage I am way more seceptible to illnesses. I got a flu shot in November, both of my kids got sick over Christmas break with the flu, I got it and then spent the last 3 months recovering from nuemonia, so I have to be extra careful to take care of myself and stay away from sick people. I hope it is successful for you as well.