Thanks guys for the responses on the Osmo Prep. Unfortunately it was slow in responding. I had a colonoscopy yeterday and had to bring a bucket in my van for the hour ride to the hospital. An alltime low! I do have a great husband though. So I have been sick for 3 months, progressively worse with two trips to Urgent Care. Anal fissure, c diff. My GI wanted to make sure what was going on, so the colonoscopy. Found my Crohn's had spread throughout and my Remicade of many years no longer working. Now I'm on Asacol and Asacol Enemas and switching to Humira. Hoping to have some luck, I was up all night sick and sick and tired of being sick like everyone else. Did have a year of remission on the Remicade. Also, I started Probiotics. Figure it can't hurt.