I had the first 4 injections done at my GI office one of the nurses did 2 of them and I did the other 2. After the burning pain of the 1st one we iced my legs ( I dont have enough scar free, stretch mark free fatty area skin on my belly they even told me just use my legs or if someone else gives me the shot it can go SQ in the arm). The ice still didnt help the burning and I felt that I wanted to rip the pen away from my leg to stop the pain.
My refills are only the syringes, I still ice my leg ***Make sure the alcohol swab dries completelly before injection since the alcohol in a cut burns it too can make this more painful***
I still have a burning feeling when I inject but at least with the syringes I can control the speed at which the humira goes in. The pharmacy screwed up and gave me the pens last month, I was off them for almost 2 months from a surgical wound infection so I will use them at the last possible chance.
I have found that the humira helps so much and I dont get the side effects that I use to get from the remicade. I still get headaches from it and I do the shot 1 every week the normal dose isnt enough for me. The headaches dont last for as many days as my ones from the remicade did plus rather than excedrine tension headache (which is just tylenol and caffeine) or my migraine meds for remicade headaches the humira ones I typically can take just tylenol
If you are using the Humira pens, then take it out of the fridge for a half an hour before you inject, so it's not so cold when you inject it. That helps very much with the pain.