Imuran versus 6-MP

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New Member

Date Joined Apr 2008
Total Posts : 1
   Posted 4/7/2008 3:08 PM (GMT -6)   
Is it possible to not tolerate 6-MP because of side effects but be able to tolerate Imuran (AZA)?

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Date Joined Nov 2003
Total Posts : 7116
   Posted 4/7/2008 4:56 PM (GMT -6)   
It depends. I do know that several members here have had problems with Imuran and when they switched to 6MP they were able to tolerate it well. So in theory it should work in reverse. HOWEVER, Imuran is metabolized into mercaptopurine in the body. 6MP is mercaptopurine.
Moderator Crohn's Disease Forum
CD, Ankylosing Spondylitis, small fiber peripheral neuropathy, avascular necrosis, diffuse connective tissue disease, Sjogren's Syndrome ?

Veteran Member

Date Joined Feb 2007
Total Posts : 734
   Posted 4/7/2008 7:45 PM (GMT -6)   
I couldn't take Imuran, it made my liver ill. I felt horrible! But that's just my individual result.

Regular Member

Date Joined Apr 2008
Total Posts : 38
   Posted 4/7/2008 7:55 PM (GMT -6)   
I've been taking Imuran since November and it helped with most of the symptoms except the killer arthritis. All of my blood work comes back ok so my liver is alright so far.

Love many, trust few, but always paddle your own canoe....

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