seems like a good day to complain...........

Flagyl sucks!
yes - 57.7%
no - 7.7%
wouldn't know - 7.7%
sucks to be you - 3.8%
cold be worse - 19.2%
UCLA sure blew it this weekend! - 3.8%

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Glad Bag
Veteran Member

Date Joined Mar 2007
Total Posts : 699
   Posted 4/7/2008 5:15 PM (GMT -6)   
I know it rarely helps to purely whine, but after reading a few posts about Humira and the bad side effects people attribute to it, I can't resist, so i thought I would chime in with my most hated Crohn's med:

Flagyl (metronidazole) aka nausea-maker aka gut-wrencher aka devil's drug

i am back on it for the time being and I can't stand it! however, I can't stand the fistulas even more, so such is life.

thanks for listening :0)
"I am he as you are he as you are me and we are all together!" - The Beatles

doesn't that just sound cool when you sing it?

Veteran Member

Date Joined Apr 2005
Total Posts : 3763
   Posted 4/7/2008 5:18 PM (GMT -6)   
I'm sorry. I know both suck. And I don't have any answers other than to comiserate with you. I hate both!!!!

CD 19 years offically, 29 unofficially. 3 resections '93, '95 '97
Symptoms constantly but all tests show only minor ulcerations. Currently having multiple episodes of gastritis with no known cause.

Prednisone, 6MP,Prevacid, B12 shots, Bentyl, Xifaxan.....

Veteran Member

Date Joined Aug 2007
Total Posts : 1202
   Posted 4/7/2008 5:46 PM (GMT -6)   
I always remember that I hate Flagyl, but was reminded a month ago when I was on it again. Lasted 10 days then I switched to Cipro. The side effects for Flagyl are the worst of any med I've taken! As if vomiting from the Crohn's weren't enough... throw in Flagyl. Sure, mouth tastes worse that imaginable, plus it makes me so nauseous! The combo, along with the Crohn's, is pretty much intolerable for me! (except when absolutely necessary!)
--39 year old female, dx as UC in '04 (1st symptoms in '03), switched to Crohn's in '05, 1 fistula, crohn's colitis, limited to large intestine
--rejected (reaction/didn't work): Asacol, AZA, 6-MP, MTX, Remicade, Humira, prednisone
--stuck on methylprednisolone, tried Prochymal in Phase III study (can't wait til it's approved!)
--started Tysabri 3/21/08
--single mom to 10-year-old girl

Veteran Member

Date Joined Feb 2007
Total Posts : 734
   Posted 4/7/2008 8:34 PM (GMT -6)   
Okay, I agree with you completely, I was on it for 7 days and again 10 days within the last month. Luckily my doctor did a Colonoscopy and saw that I didn't need it. I hate Flagyl it makes me feel horrible. I can't exactly describe it either, but just yucky all around!

Veteran Member

Date Joined May 2007
Total Posts : 1220
   Posted 4/7/2008 8:37 PM (GMT -6)   
I was on it for about 3 months last year. Well, I hated the nasty side effects but, it saved my life. But I got tingly and sensitive feet so that's it for me.

New Member

Date Joined Jan 2008
Total Posts : 11
   Posted 4/7/2008 9:21 PM (GMT -6)   
After one dose many years ago, the nausea and dizziness were incredible. The doctor took me off it right away. Add to that the tongue fur which lasted for ages after - I hope I never have to consider taking it again. With the dizziness, I could barely stand up.
50 years with Crohn's and still going (no pun intended)! Diagnosed in 1958.

Veteran Member

Date Joined May 2007
Total Posts : 1488
   Posted 4/7/2008 9:38 PM (GMT -6)   
When taking Flagyl...if I could get off the toilet long enough, I MIGHT be able to tell if it's day or night!
It's a necessary evil at times but I put it right up there with the prednisone....just plain crappy!
Dx'd Jan'06, 1st Resection 7/06, Predinsone, Humira, Imuran, B12 injections, Nexium. Secondary conditions: Psorasis, Acne, Fatigue, Joint Pain, Lactose Intolerant, gallstones, fibroid cysts, peri-menopausal.

Veteran Member

Date Joined May 2005
Total Posts : 4219
   Posted 4/7/2008 9:56 PM (GMT -6)   
Don't forget no alcohol w/ Flagyl or you will get super sick! Also for the ladies, Flagyl cancels out birth control (which is how my friend is pregnant with a little girl!!) so in the slim chance you feel randy on the Flagyl... use other protection... Finally - regarding the icky taste from Flagyl, I wrapped the pill in my little brother's fruit roll ups or fruit by the foot to make it more like a gel-cap. It really reduced the icky metalic taste in the mouth. I don't know if it effected the drug's release at all but frankly I could have cared less if it meant I didn't have to taste it anymore.
26 Year old married female.  Diagnosed w/ CD 3 years ago, IBS for over 10 years before that, which was probably the CD.  Currently on Pentasa 4 pills/4x day, hysociamine prn, nexium, and ortho evra.  Good times!!!

Regular Member

Date Joined Feb 2008
Total Posts : 31
   Posted 4/8/2008 7:01 AM (GMT -6)   
Flagyl is horrible!!  Not only the dizziness, horrible taste, and nausea...I could not concentrate on reading anything.  Even a recipe, I would read it, try to do step one and have to reread it because I could not remember what I had just read.  Hate it, that and prednisone!  As sr5599 said, my GI switched my to Cipro, I still felt slightly nauseaous but nothing like when I was on the Flagyl.  How this helps.

Diagnosed 1972 with UC (12 years old); many flares over the years
1994 had my son and became very ill; took 4 years to get the correct diagnosis.
PCP diagnosed with IBS and was down 70lbs. by the time I insisted on seeing a specialist.
1997 Diagnosed  with Fistulizing Crohn's
1998 had 1ft. of small intestine removed including terminal illieum, have had constant diarrhea since.
Currently taking imuran, prilosec, synthroid, zoloft, xanax & B12

Veteran Member

Date Joined Feb 2007
Total Posts : 734
   Posted 4/8/2008 3:11 PM (GMT -6)   
Wow, I love the trick of wrapping it in a fruit wrap. What a terrific idea!

Regular Member

Date Joined Mar 2007
Total Posts : 301
   Posted 4/9/2008 8:23 AM (GMT -6)   
Hi Nat,
sorry to hear that you are having to take medication that makes you feel even worse.I sure hope that you feel better soon!

:) I hope that you have a good day!
Official Crohns DX-march 2004.Pentasa 4000mg,B12,Probiotics
         1 resection
Cardiomyopathy DX-may 2004.Coreg,Altace,Digitek,Lasix,Potassium,very low-sodium diet

Regular Member

Date Joined Apr 2007
Total Posts : 345
   Posted 4/10/2008 3:49 PM (GMT -6)   
Flagyl sucks because it never comes coated and it melts instantly on your tongue and no matter how far back you put it, you can always taste it.

I just lied to my gi and told her i finished my flagyl - i never took it. (i know i'm bad--but i didnt need it that bad, she likes to throw it at me every time my fistula opens to drain).
33 years old. Diagnosed in 2002ish. 
Taking Asacol, Lomotil TID, and on Remicade since 2004. 
Lower Bowel area only, except for the short stint (about 2 weeks) that I had mouth sores.  Also have external/anal fistula and anal/vaginal fistula. 

Glad Bag
Veteran Member

Date Joined Mar 2007
Total Posts : 699
   Posted 4/10/2008 5:11 PM (GMT -6)   
yeah, i've done that a few times myself....
"I am he as you are he as you are me and we are all together!" - The Beatles

doesn't that just sound cool when you sing it?

Regular Member

Date Joined Jul 2006
Total Posts : 330
   Posted 4/13/2008 2:05 PM (GMT -6)   
I'm allergic to it - full fleged allergic reaction to it in the hospital -so no more flagyl for me. (The only thing is I hope I never get C-difficile because I hear flagyl is the only effective antibiotic for it)

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