I have been getting the Remicaid infusions for about four years, and now it seems to be failing. I am so afraid Crohn's is taking over I just had my infusion less than two weeks ago and I am seeing blood again from my bottom. It is to soon for me to have the next infusion, its not till may 7th. I am not sure what to do. I am planning to call my GI guy Monday and ask if I can try Humira, I am getting desperate. I feel that each passing day I have fewer and fewer hours in the day that I feel good. I know that I have to do something, has anyone changed from Remicaid to Humira and had good results? My pain level has increased and my abdomen feels swollen. I know it's not a blockage as I know how that feels, it feels inflamed inside and I have been so nausious lately, I can't go on like this. I just passed up a wedding invitation today as I fear going and getting sick, it's making me crazy. Also my pain management is slipping and I am back to counting the hours until I can take my pain meds. this is so messed up. I just can't go through the tests that might await me if I open up this can of worms again.