remicade versus humira

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poobah
Regular Member


Date Joined Dec 2006
Total Posts : 136
   Posted 5/6/2008 4:09 PM (GMT -7)   
my doc seems to be giving me a choice between the two. id feel better if he would just tell which is safer, or better tolerated straight up.
 
anyone have any insight into this?
 
yeah, yeah, im gonna google it ofcourse. just wondering if anyone has any personal insight, or if their doc prefered one over the other for a specific reason.
 
thanks.

ivy6
Elite Member


Date Joined Sep 2005
Total Posts : 10404
   Posted 5/6/2008 4:47 PM (GMT -7)   
Do you live in a country with subsidised medicine? Or are you in the US? If so, your insurance company might have something to say about your situation too.
Co-Moderator Crohn's Forum.


potatoqwn
Regular Member


Date Joined Jan 2006
Total Posts : 355
   Posted 5/6/2008 8:35 PM (GMT -7)   

I took Remicade over the course of two years or so.  I had only a mildly positive response to it.  I had to stop when I developed a reaction to it.  I did not like the amount of time it took out of my life each time for the infusion. I work and I would have to take a day off each time due to the drive to the place, the pre-medication and finally the infusion which always had to be slowed down due to problems/reactions. 

I have been on Humira two years now and am in remission.  This is my first ever remission in over 15 years since my diagnosis.  It took about 3 months for me to go into remission.  I like the ease of the injection (once every two weeks) and have had no real side effects.  I do get a large welt all around the injection site for a day or two, but that is about it.   


BillyLitt
Regular Member


Date Joined Dec 2006
Total Posts : 53
   Posted 5/7/2008 9:07 AM (GMT -7)   
Between the two, your most likely to reject the Remicade because it contains mouse proteins.  Not a bad thing, but your body is more likely to detect the mouse protein as an intruder and attack it, causing your body to reject the medication.
 
My wife was on it for about 7 months and she rejected it.  Real bad joint pain was the symptom, easily reversed when she stopped Remicade treatment.
 
She switched to Humira and she is doing fine with it.
 
If it was me, I would go with Remicade.  It takes a few hours to get, but it works for a large number of people.  If or when you develop antibodies, you can move to the next drug, Humira.
 
The way my wife and I look at it is each of these meds is just another step closer to a cure.  All these meds are doing is buying each patient time.  I believe two other drugs were released after Humira, and probably more to come.

ZenaWP
Veteran Member


Date Joined Aug 2007
Total Posts : 884
   Posted 5/7/2008 9:19 AM (GMT -7)   
I would go with Humira, if your insurance will approve it. The reactions many people have to Remicade can be very scary and it is much less convenient than giving yourself the Humira injection.
...rejoice in our sufferings, because we know that suffering produces perseverence; perseverence, character; and character, hope.   Romans 5:3-4


Eddie K.
Regular Member


Date Joined May 2008
Total Posts : 27
   Posted 5/7/2008 1:14 PM (GMT -7)   
Good points.  My doc wants me to start on Remicade because he's got more experience with it but I would feel more comfortable with Humira due to humanized antibody, ease of administration, cleaner label, etc. 
Has anyone been in a similar situation and was able to convince a doc to go with one and not the other?

Crohn'snme
Veteran Member


Date Joined Feb 2007
Total Posts : 734
   Posted 5/7/2008 8:22 PM (GMT -7)   
HUMIRA FOR SURE. I was on Remicade for over three years, expensive, time consuming and mediocre. Humira, cheaper, take at home and much better results for myself. Hope this helps.
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