Crohns Enigma Close to being solved???

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

Doc2007
Regular Member


Date Joined Oct 2007
Total Posts : 294
   Posted 5/8/2008 1:18 PM (GMT -7)   

sjkly
Veteran Member


Date Joined Dec 2007
Total Posts : 2113
   Posted 5/8/2008 3:11 PM (GMT -7)   
I haven't seen this before. It is quite interesting.
Sj

dunny2
Veteran Member


Date Joined Jan 2007
Total Posts : 3200
   Posted 5/8/2008 3:23 PM (GMT -7)   
Thanks Doc, that was very interesting. I've heard about Viagra for treating crohns before, but never really understood it's use.
So at least that was clarified for me. Lets hope this could be a real break through!!
Vicky

Too many years with CD
Two bowel resections, several obstructions.
Fibromyalgia and recently diagnosed with pancreatitis

Laughter is the brush that sweeps the cobwebs from our hearts


meandmyhunny2
Regular Member


Date Joined Feb 2007
Total Posts : 90
   Posted 5/8/2008 4:25 PM (GMT -7)   
wow what an interesting way of looking at it! it could possibly help us heel and ''enhance our love lives'' lol meandmyhunny2
 


potty pooper
Regular Member


Date Joined Dec 2006
Total Posts : 375
   Posted 5/8/2008 4:54 PM (GMT -7)   
Thanks for the info. Hope this will be an answer. But I would concerned as to how Viagra would affect women.

sr5599
Veteran Member


Date Joined Aug 2007
Total Posts : 1202
   Posted 5/8/2008 4:59 PM (GMT -7)   
Not wanting to be pessimistic, but the article was written in 2/06. If it were a valid theory it seems like they would have advanced it and we would have read more about it. Also, I thought Viagra had not panned out in Crohn's. I could certainly be wrong! I'd love to think they were "on to it!"!!!!
--40 year old female, dx as UC in '04 (1st symptoms in '03), switched to Crohn's in '05, 1 fistula, crohn's colitis, limited to large intestine
--rejected (reaction/didn't work): Asacol, AZA, 6-MP, MTX, Remicade, Humira, prednisone
--stuck on methylprednisolone, tried Prochymal in Phase III study (can't wait til it's approved!)
--started Tysabri 3/21/08
--single mom to 10-year-old girl


CrohnieToo
Veteran Member


Date Joined May 2003
Total Posts : 9448
   Posted 5/8/2008 5:07 PM (GMT -7)   
Wasn't, isn't, it Tysabri or is it Leukine, that was developed on the theory that our immune systems are insufficient rather than the more common theory that is it over-active? Talk about two conflicting theories!!!
Some people are like Slinkies... Not really good for anything, but they still bring a smile to your face when you push them down a flight of stairs.


Reef08
Regular Member


Date Joined Dec 2005
Total Posts : 267
   Posted 5/8/2008 5:25 PM (GMT -7)   
That would be Leukine. It failed in the trials.

Crohn'snme
Veteran Member


Date Joined Feb 2007
Total Posts : 734
   Posted 5/8/2008 7:55 PM (GMT -7)   
I'm confused?

sr5599
Veteran Member


Date Joined Aug 2007
Total Posts : 1202
   Posted 5/8/2008 9:03 PM (GMT -7)   

I tried to get into a leukine trial, but they were already done.  I've wondered about off-label, though... 

Yes, two completely opposing theories.  One to boost the immune system, the other to nearly kill it.  makes me wonder...  I hope that the stem cell theories can pan out.  It would be great to think that there were a way to re-set the immune system.  if the theory of autoimmune is correct...  But, it's what I hold my hope for.  This suppressing the immune system stinks.


--40 year old female, dx as UC in '04 (1st symptoms in '03), switched to Crohn's in '05, 1 fistula, crohn's colitis, limited to large intestine
--rejected (reaction/didn't work): Asacol, AZA, 6-MP, MTX, Remicade, Humira, prednisone
--stuck on methylprednisolone, tried Prochymal in Phase III study (can't wait til it's approved!)
--started Tysabri 3/21/08
--single mom to 10-year-old girl


poobah
Regular Member


Date Joined Dec 2006
Total Posts : 136
   Posted 5/9/2008 4:45 AM (GMT -7)   
the problem with the immune sytem is that it is both too strong and too weak.

our immune system regulates itself through a myriad of chemical pathways that tell it when and what defense to switch on, and when to turn it off. i suspect people with crohn's are simply dysregulated.
New Topic Post Reply Printable Version
Forum Information
Currently it is Wednesday, December 07, 2016 11:31 AM (GMT -7)
There are a total of 2,734,160 posts in 301,185 threads.
View Active Threads


Who's Online
This forum has 151309 registered members. Please welcome our newest member, waterfall79.
370 Guest(s), 15 Registered Member(s) are currently online.  Details
momto2boys, Psilociraptor, Tagier, 81GyGuy, Jen77, Skyy, Loutucky, Girlie, pmm73, maria2016, quincy, catti, poopme, ljimd, julymorning


Follow HealingWell.com on Facebook  Follow HealingWell.com on Twitter  Follow HealingWell.com on Pinterest
Advertisement
Advertisement

©1996-2016 HealingWell.com LLC  All rights reserved.

Advertise | Privacy Policy & Disclaimer