crohn's disease passed on to children

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sabobrien2006
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Date Joined May 2008
Total Posts : 1
   Posted 5/31/2008 10:26 AM (GMT -7)   
My boyfriend has just found out he has crohn's. But we have two children and we are worried they might get it. Does anyone know what the chances are of them getting it?

Howlyncat
Elite Member


Date Joined Jan 2005
Total Posts : 24909
   Posted 5/31/2008 12:02 PM (GMT -7)   
There have been posts of the nature that does point to CD being hereditary
I know I truly believe it
BUT that does not mean it will be 100 %

I want to welcome you to HW and let you know to read back thru some of the old posts and the mom's with kids that have CD I know will post as will others
It is always slower on the wknd
STAY with us and dont stress out ....
Check out Resources as well .......

Take care and again Welcome......LYN


  DX With Crohns,Pyoderma Gangrenosum,Anxiety/Panic,Fibro & Other DD
 
Moderator @ Anxiety Panic..Alzheimer's..Co mod @ Crohns
                               FIGHT the FIGHT with all YOU HAVE
 
   
 
                   
 

Post Edited (Howlyncat) : 6/1/2008 9:03:25 AM (GMT-6)


TraciZ
Regular Member


Date Joined Aug 2007
Total Posts : 255
   Posted 5/31/2008 12:26 PM (GMT -7)   
There's a genetic component, but that's not the be all/end all. For instance, no one else in my family is sick. There are lots of other factors that may contribute. There's something called the diathesis-stress model. It says that a person can have a genetic susceptibility to an illness, but it needs an environmental trigger. Also, there's been some discussion lately about johnes disease in cows contributing to crohn's in humans. I undrstand your concern; I have 2 kids. But, my philosophy is that there's no sense worrying about what might be, especially if you can't control it. After all, what can you do even if it was certain they'd get it? Best Wishes!
Tressa 34 (F)
Not sure of my dx- currently UC, maybe Crohn's.
Colazal 3X3/day
Lialda upped to 4/day,
Phosphatidylcholine 4 (420 mg capsules) once/day
Colazal 3X3/day (not generic)
Rowasa at night X 14 days
Canasa BID


pb4
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Date Joined Feb 2004
Total Posts : 20576
   Posted 5/31/2008 2:04 PM (GMT -7)   

Here's a link about this being discussed here at HW a short time ago...

http://www.healingwell.com/community/default.aspx?f=17&p=1&m=1097650

 My mom has UC (also an IBD) and I have crohns, so far I'm her only child out of 6 that got IBD like her.

According to research if one parent has IBD (either CD or UC) their offspring has an estimated 10- to 15- fold increased rish of developing IBD compared with those who don't have a parent with IBD....parents are not necessarily the only way it can be passed down.

Also, smoking (including second hand smoke) is one known trigger for CD specifically.

:)


My bum is broken....there's a big crack down the middle of it!  LOL  :)


Jen77
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Date Joined Mar 2006
Total Posts : 2691
   Posted 5/31/2008 3:28 PM (GMT -7)   
We believe there are members in our family that have it besides myself. We think some had mild cases and never got treatment. Then there is my Aunt that I'm darn sure has it, but hasn't been diagnosed yet.

But it doesn't seem to pass down that directly in my family. Neither of my parents have it for instance. So I'm hopeful that it will skip my ds.

I look at it this way though. Every family has something bad in it, that can be passed down. It's just a part of life.
~Jennifer
 
Diagnosed with Crohn's Disease 2/06 after sever GI bleed. Has been suffering since 1998. History of rectal fistula and gallbladder removal. Currently taking Prednisone: tapered to 30 mg, Asacol, Questran, Toprol XL (for high blood pressure).


MMMNAVY
Veteran Member


Date Joined Jul 2006
Total Posts : 6927
   Posted 5/31/2008 3:50 PM (GMT -7)   
NO one in my family has it that we know of. That is about six generations. Mine started in the military and I think an sting and infection started it.
Forum Co-moderator - Crohn's Disease
We will find a way, or make one.-Hannibal (crossing the Alps in the 15th Century on war elephants) 
Make sure your suffering has meaning...-?
All suggestions/options/opinions are caveated with please consult with your local health care provider...


LBJ
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Date Joined May 2005
Total Posts : 511
   Posted 5/31/2008 4:11 PM (GMT -7)   
No one in my family has it either and I come from a pretty big family. Unless Great grandparents had it many years ago.

But I'm like someone else said, we can't predict the future and why worry about it? My son is 2 and if he should come
down with it, I'll be right there by his side. With me having it he will have all the help he can possibly have.

inflamed
Veteran Member


Date Joined Nov 2005
Total Posts : 1340
   Posted 5/31/2008 8:24 PM (GMT -7)   
I have CD and my hubby is suspected of having it (no one in either of our families has it). Our first child is coming this summer, but we've decided not to be concerned.

What I've been told is that when one parent has CD the chance of a child getting CD is not significantly greater than the general population (I forget the percentage). The rate is higher when both parents have IBD, BUT you have to remember many people have genes linked to this disease and they never get sick. Genetics is only one factor. There also needs to be a trigger. Your children may not have the genes to be susceptible and even if they do, it may never be triggered. I don't think it is worth worrying about. If you have to deal with it down the road, no one would be better prepared.
Currently in remission!


pb4
Elite Member


Date Joined Feb 2004
Total Posts : 20576
   Posted 5/31/2008 8:34 PM (GMT -7)   
inflamed said...
I have CD and my hubby is suspected of having it (no one in either of our families has it). Our first child is coming this summer, but we've decided not to be concerned.

What I've been told is that when one parent has CD the chance of a child getting CD is not significantly greater than the general population (I forget the percentage). The rate is higher when both parents have IBD, BUT you have to remember many people have genes linked to this disease and they never get sick. Genetics is only one factor. There also needs to be a trigger. Your children may not have the genes to be susceptible and even if they do, it may never be triggered. I don't think it is worth worrying about. If you have to deal with it down the road, no one would be better prepared.

According to research if one parent has IBD (either CD or UC) their offspring has an estimated 10- to 15- fold increased rish of developing IBD compared with those who don't have a parent with IBD....parents are not necessarily the only way it can be passed down.
 
:)

My bum is broken....there's a big crack down the middle of it!  LOL  :)


MMMNAVY
Veteran Member


Date Joined Jul 2006
Total Posts : 6927
   Posted 6/1/2008 6:08 AM (GMT -7)   
From a journal on pubmed or jstor (I forget) the risk is about 2% if parent has an IBD (which is academically researched), and I have seen it as high as an estimated 8-20% in some books (which I still question the validity of because I did not see an academic cite), but in all honesty all you can do is observe and deal with things as they come. Believe me I am much more concerned about their car and home safety then them developing this disease, their risk statistically is much higher there. (this is no reflection on you, it is just a statistically their are more at risk in the car and from home accidents, then crohns disease)

To answer your question their risk is low. Granted having one parent with this DD does increase their chances of getting it in comparison with children who do not have parents with this darn disease (who are still at risk of developing this disease), but there really is not much you can do to stop it all you can do is be vigilant.
Forum Co-moderator - Crohn's Disease
We will find a way, or make one.-Hannibal (crossing the Alps in the 15th Century on war elephants) 
Make sure your suffering has meaning...-?
All suggestions/options/opinions are caveated with please consult with your local health care provider...

Post Edited (MMMNAVY) : 6/1/2008 9:18:47 AM (GMT-6)


Mormor Vicky
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Date Joined Mar 2007
Total Posts : 684
   Posted 6/1/2008 7:28 AM (GMT -7)   
Sometimes I wonder if it can be passed up.  Just kidding.  My daughter was diagnosed with Crohn's when she was 12.  Now 27.  I was diagnosed 2 years ago.  We both do worry about my granddaughter.  She is 7 and is as tiny as they come.  34 lbs.  She also always complains about tummy problems.  Her peditrician is aware and it's possible she complains about her tummy because she hears her mom and grandma talk about our tummies. 
Vicky / 48 years old
DX'd with Crohn's during a resection August 2006
DX'd with Steriod induced Diabetes November 2006
Considered in Clinical remission but have minor signs of disease activity
 
Daughter (27) also has Crohn's since she was 12.
 
Currently on 4000mg of Pentasa only for Crohn's
No longer able to take 6-MP because of Bone-Marrow Suppression
Cymbalta, Metformin, Lipitor


Howlyncat
Elite Member


Date Joined Jan 2005
Total Posts : 24909
   Posted 6/1/2008 8:02 AM (GMT -7)   
Vicky
My Cait has c/o about her tummy and many of her bowels movements are painful

She has seen me at the worst and has had to clean up after me having accidents

I am having her checked but my doc thinks it is the same thing as what your GD is going thru.......

Cait is always on the go and is not taking the time to eat properly IMHO

I DO know I will be there IF it is .......
But I seriously dont think it is the case.........
MY GMA and MOM both had Diverticulitis and I believe Mom also had IBD

Take care........LYN
  DX With Crohns,Pyoderma Gangrenosum,Anxiety/Panic,Fibro & Other DD
 
Moderator @ Anxiety Panic..Alzheimer's..Co mod @ Crohns
                               FIGHT the FIGHT with all YOU HAVE
 
   
 
                   
 


racerswife
New Member


Date Joined Jun 2008
Total Posts : 5
   Posted 6/2/2008 8:05 AM (GMT -7)   
My Mother has UC & Lupus, her mother has Fibromyalgia and IBS. I have Crohn's. My brother is healthy. All my mother's brothers (3 of them) are healthy. No one else in my family shows signs of UC or Crohn's.
Diagnosed w/Crohn's @ 19.
Currnetly taking Lialda and Prenatal Vits


pianogrl
New Member


Date Joined May 2008
Total Posts : 4
   Posted 6/2/2008 12:14 PM (GMT -7)   

My doctor said that it is more likely for siblings to have Crohns than for a parent to pass it on to a child.

However, I have crohns, and my grandmother has crohns.  My mom doesn't have hardly any symptoms.  But, my grandmother and I have almost the exact same complications and symptoms.  She has had 3 bowel resections and I am looking like I might have to have one this summer.

So, who knows really.  My sister went in last week, just make sure about things, and hasn't heard back yet. 

 

 


pb4
Elite Member


Date Joined Feb 2004
Total Posts : 20576
   Posted 6/2/2008 12:28 PM (GMT -7)   
pianogrl said...

My doctor said that it is more likely for siblings to have Crohns than for a parent to pass it on to a child.

However, I have crohns, and my grandmother has crohns.  My mom doesn't have hardly any symptoms.  But, my grandmother and I have almost the exact same complications and symptoms.  She has had 3 bowel resections and I am looking like I might have to have one this summer.

So, who knows really.  My sister went in last week, just make sure about things, and hasn't heard back yet. 

 

 


Researchers know...

According to research if one parent has IBD (either CD or UC) their offspring has an estimated 10- to 15- fold increased rish of developing IBD compared with those who don't have a parent with IBD....parents are not necessarily the only way it can be passed down.

This is the conclusion they've come to learn as of now...it's not to say that it can't skip generations but there is definitely a link to a parent having IBD and the increased risk of their offspring developing it as well...my mom has UC.

:)


My bum is broken....there's a big crack down the middle of it!  LOL  :)


patientspiders
Veteran Member


Date Joined Jul 2005
Total Posts : 733
   Posted 6/2/2008 8:30 PM (GMT -7)   
This is a personal answer, not a medical one.

When I was diagnosed, I KNOW that my parents racked their brains trying to figure out if there was something that they could have done differently. For the first couple years, they felt a lot of guilt, I think, as I tumbled through surgeries and an official diagnosis. That being said...

I am thankful for EVERY day that I am on this earth, crohns or not. If you give your kids the kind of love my parents gave me, everything will turn out fine.

Best of luck to you and yours.
26f, dx'd CD July '05 after 6 fistula/abscess surgeries
Remicade only, every 16 weeks.
Digestive enzymes, and probiotics.
Doing pretty darn good, all things considered. :-)

"Our greatest fear is not that we are inadequate, but that we are powerful beyond measure."

~Marianne Williamson

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