Researchers to test stem cells to treat Crohn's

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MamaDove
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Date Joined Dec 2006
Total Posts : 181
   Posted 6/18/2008 10:40 AM (GMT -7)   

pb4
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Date Joined Feb 2004
Total Posts : 20576
   Posted 6/18/2008 11:47 AM (GMT -7)   

Very interesting...in the link you posted it states "donors" would be used to retrieve stems cells...

In this link...

http://www.sciencedaily.com/releases/2007/11/071130223834.htm

it states they would actually use the cells from the patients own bone marrow and re-entered into themselves.

It's great to see that they are still investigating into this option...the link I provided above sounds more like it would be along the lines of an actual "cure" for up to 50% of sufferers.

Can't wait to see how this all progresses, I just hope it's fast.

 

:)



My bum is broken....there's a big crack down the middle of it!  LOL  :)


dunny2
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Date Joined Jan 2007
Total Posts : 3200
   Posted 6/18/2008 12:39 PM (GMT -7)   
Thanks for the info. Definitely, food for thought!!
Vicky

Too many years with CD
Two bowel resections, several obstructions.
Fibromyalgia and recently diagnosed with chronic pancreatitis

Laughter is the brush that sweeps the cobwebs from our hearts


ivy6
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Date Joined Sep 2005
Total Posts : 10404
   Posted 6/18/2008 5:24 PM (GMT -7)   
Is this Prochymal?

And is the Stonybrook they mentioned the same Stonybrook where the Baby Sitters' Club books were set?
Co-Moderator Crohn's Forum.


MamaDove
Regular Member


Date Joined Dec 2006
Total Posts : 181
   Posted 6/19/2008 4:34 AM (GMT -7)   
Stony Brook University is on Long Island,NY...A wonderful doctor there saved my niece who was facing a no-win battle with neuroblastoma, she was 2 at the time...Today, she is a beautiful 15 year old living life to the fullest...Fantastic Hospital and staff!!!

sr5599
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Date Joined Aug 2007
Total Posts : 1202
   Posted 6/19/2008 7:42 AM (GMT -7)   
I was wondering the same thing - if it's Prochymal. It sounds like it -- adult bone marrow donors, made into an infusion and the fact that the patients had to have failed every other type of medication. But, why wouldn't they use the name for publicity?

One thing I read in that article that i'm not so sure about (but I'm far from an expert!)... It said that the stem cells "are essentially blank slates capable of morphing into any kind of cell". I thought this was true of fetal stem cells but *not* adult stem cells. I thought adult stem cells could only become 4 types of tissue.
--40 year old female, dx as UC in '04 (1st symptoms in '03), switched to Crohn's in '05, 1 fistula, crohn's colitis, limited to large intestine
--rejected (reaction/didn't work): Asacol, AZA, 6-MP, MTX, Remicade, Humira, prednisone
--methylpred - finally off 6/15/08, tried Prochymal in Phase III study (can't wait til it's approved!)
--started Tysabri 3/21/08, started Xifanan 5/24/08 
--single mom to 10-yr-old girl


Poopington McToot
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Date Joined Jul 2005
Total Posts : 315
   Posted 6/19/2008 12:38 PM (GMT -7)   
sr5599 said...
...the fact that the patients had to have failed every other type of medication....
Does anyone know why this is limited to this particular type of patient?  If it works, I would love to give it a try and I've been fairly responsive to meds over the years.
 
Poopington McToot
It's easy to grin, when your ship comes in...and you've got the stock market beat.  But the man worthwhile, is the man who can smile, when his shorts are too tight in the seat.


Reef08
Regular Member


Date Joined Dec 2005
Total Posts : 267
   Posted 6/19/2008 1:56 PM (GMT -7)   
Yup, it's Prochymal. 

not creative
Regular Member


Date Joined Mar 2007
Total Posts : 466
   Posted 6/19/2008 3:07 PM (GMT -7)   
"Two weeks ago the Food and Drug Administration announced an investigation into three drugs that tamp down the immune system, following 30 reports of children and young adults who developed cancer."


Anyone know what that's referring to??

Also, I'm so glad that stem cells are finally becoming a viable option- I've been a huge supporter for years for this very reason.
Laurenne, 23 Student @ University of California, Davis.
Dx'd w/ IBS and CD in 2002
On Humira, Strattera, Zoloft, (Multivitamin, Flax Oil, and Omega complex when I remember.)


njmom
Veteran Member


Date Joined Apr 2006
Total Posts : 1884
   Posted 6/21/2008 6:42 PM (GMT -7)   

The drugs under review include Abbott Labs' Humira, Schering-Plough's Remicade, and Enbrel, which is marketed by Amgen Inc. and Wyeth.

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