can you take excedrin?

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Date Joined Feb 2008
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   Posted 6/21/2008 3:57 PM (GMT -6)   
I know we're not supposed to have meds with aspirin but I'm dealing with a headache--again--that only seems to go away with excedrin. Is it really a real no-no? Anyone take it regularly? Any other ideas?
23 years with moderate Crohn's/colitis; fistulizing crohn's; pentasa

Veteran Member

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   Posted 6/21/2008 4:11 PM (GMT -6)   
I usually take advil with no problems.
Living with Crohn's Disease since Jan./2000 but had a few years prior
I'm a true Crohnie with IBS too
Meds I have tried:  Just about everything 
Meds currently on:  Prednisone 30mg tapering
                           Methotrexate injection 12wks
                           Folic Acid
No Surgeries

Crohn's 4 ever
Regular Member

Date Joined May 2008
Total Posts : 207
   Posted 6/21/2008 4:44 PM (GMT -6)   
Yes, I can see why you asked, been on Pentasa before, and I think I took Tylenol, or advil. Just harder on your stomach too take too many asprin with Pentasa, I would think. Call your pharmacy, they know their drugs. Good luck, I usually dont get headaches, only some meds cause it.
Tough times don't last long, tough people do!

Post Edited (Crohn's 4 ever) : 6/21/2008 4:00:54 PM (GMT-6)

Veteran Member

Date Joined Oct 2004
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   Posted 6/21/2008 5:57 PM (GMT -6)   
Hi, asprin, are a no-no. Tylenol we can take.
Hi, I am teddybearweiser, I am a male.
I was diagnosed with crohns disease when i was admitted to the hospital

in 1992, in Jan of 1993 I was back in the hospital for surgery for my crohns. I had part of my right colon resectioned with ilecolonstomy.

My GI doctor has me on Asacol, Dicyclomine,Imuran,Celebrex and Remicade. B-12 injection once a month.
Also diagnosed with Osteoarthritis and Rheumatoid Arthritis

Veteran Member

Date Joined Nov 2005
Total Posts : 1338
   Posted 6/21/2008 7:50 PM (GMT -6)   
ditto teddybearwiser. Basically, don't take anything that has a warning of stomach bleeding. That pretty much leaves Tylenol or Rx meds.
Currently in remission!

Elite Member

Date Joined Feb 2004
Total Posts : 20552
   Posted 6/21/2008 8:43 PM (GMT -6)   
Anything with NSAIDs in them is a no no, advil, aspirin and anything eles that contains NSAIDs as it promotes bleeing in the bowels, and that's why we should not be taking them. Any good GI will warn their patients of this.

My bum is broken....there's a big crack down the middle of it!  LOL  :)

Regular Member

Date Joined Oct 2007
Total Posts : 208
   Posted 6/21/2008 9:35 PM (GMT -6)   
Yeah, advil definitely  a no-no. Having said that, when I get headaches, Tylenol doesn't touch it. Unless I want it to turn into a cripling migraine and be useless for the next two days I have to take Excedrin. Basically I weigh the options: more bleeding or headaches that make it even painful to blink, not kidding, AWFUL pain. I try to wait it out for as long as possible, but when the pain is so bad I can't sleep, or I wake-up at 4 am and am unable to get out of bed to get meds, I take the risk and try to head it off the next time I feel that way. Guess it's really just a personal call.

Pentasa- 1000mg/2x 1/08; Percocet/Ultram for pain; Prilosec 40mg; Xanax-ANXIETY; Cymbalta 60mg
Ferrous Sulfate 325mg/daily for anemia
Azathioprine 150mg
Currently on a Low-residue diet as of 11/26

I'm so tired, when will this get better?

Veteran Member

Date Joined Dec 2007
Total Posts : 2113
   Posted 6/21/2008 9:49 PM (GMT -6)   
I would try two tylenol with a dose of cafeen-cola, cofee, or a cafeen pill. It is the cafeen in excedrin that makes it work so well.

Elite Member

Date Joined Apr 2005
Total Posts : 14995
   Posted 6/22/2008 11:49 AM (GMT -6)   
I think Kasper87 is doing it the smart way. Its tylenol and caffiene. But, I also (very rarely) when I get a bad headache will take one Aleve. Once in a blue moon isn't bad, but not daily or even on frequent schedule. Just once in a blue moon as I said. But NSAIDS are big no no's for us.
Been living with Crohn's Disease for 32 years.  Currently on Asacol, Prilosec 60 mg, Estrace, Prinivil, Diltiazem, Percoset prn for pain and Calcium.  Resections in 2002 and 2005.  Recently diagnosed with Fibromyalgia and doing tests to see if I have Inflammatory Arthritis or AS.

Regular Member

Date Joined Feb 2008
Total Posts : 71
   Posted 6/22/2008 12:31 PM (GMT -6)   
this is a very interesting thread to me.. i take excedrin migraine on a fairly regular basis because it works better and faster than advil, tylenol, aleve etc. i've been having bleeding for the past few months.

imma stop taking anything but tylenol/caffeine and see what happens. my GI never mentioned this to me. perhaps i should look for a new one as i haven't gotten that 'warm and fuzzy' feeling from him anyway.
.:brad:. 23 year old male from PA.

diagnosed with crohn's disease in april 2002 during surgery for obstruction
meds: 50mg 6-MP, folic acid

Regular Member

Date Joined Sep 2007
Total Posts : 182
   Posted 6/22/2008 12:51 PM (GMT -6)   
Excedrin is not a problem @ all (from my experience). I always take it when I have a headache or start of a migraine and it is the only thing that gives me any relief! Obviously, taking any pain medication too much isn't good but you are not doing that!

Good Luck!
I have had Crohn's since I was 21 years old and I am now 27....

On HUMIRA, on and off of prednisone temperarily 20mg right now....
Multivitamin, Probiotics, iron, fish oil

Unfortunately, nothing has worked for me. But I will keep on going and trying everything possible!

Also recovering from a blood clot in my lung and of course the blood thinners really messed up my bleeding from my Crohn's....

Elite Member

Date Joined Apr 2005
Total Posts : 14995
   Posted 6/22/2008 6:40 PM (GMT -6)   
Br4d & lovepink if you are wondering why you are bleeding so much, it is probably because of your NSAID use. NSAIDS are major no-no's for us because they cause bleeding in our intestinal tracts. You will never get your Crohns under control if you continue using them. I learned this the hard way. Please stop taking them. I take pain meds prescribed by my family doc. All of our prescribed pain meds are always with Tylenol in them no aspirin, ibruprofen or Naproxen type meds for us.
Been living with Crohn's Disease for 32 years.  Currently on Asacol, Prilosec 60 mg, Estrace, Prinivil, Diltiazem, Percoset prn for pain and Calcium.  Resections in 2002 and 2005.  Recently diagnosed with Fibromyalgia and doing tests to see if I have Inflammatory Arthritis or AS.

Veteran Member

Date Joined Oct 2004
Total Posts : 3932
   Posted 6/22/2008 7:01 PM (GMT -6)   
I've never had a problem with it, or aspirin for that matter. Still, I'd be cautious using any 5 ASA drug with either...


Elite Member

Date Joined Feb 2004
Total Posts : 20552
   Posted 6/22/2008 8:43 PM (GMT -6)   
5ASA drugs are different than NSAIDs.

5-ASA is poorly-absorbed by the intestines, and hence provides topical relief within the intestine. It is therefore a non-systemic drug. 5-ASA is related to the systemic non-steroidal anti-inflammatory drugs (NSAIDs), such as Aspirin and Ibuprofin.

The free radical induction theory, discussed above, proposes that 5-ASA is serving not just as an anti-inflammatory, but also as a free radical trap, destroying the hydroxyl and other radicals that may damage colonic epithelial barrier.[2]


My bum is broken....there's a big crack down the middle of it!  LOL  :)

Post Edited (pb4) : 6/22/2008 7:50:53 PM (GMT-6)

Regular Member

Date Joined Jan 2006
Total Posts : 355
   Posted 6/22/2008 10:39 PM (GMT -6)   
I have no problems taking Advil or Excedrin. I get migraines, and Tylenol does not touch that pain at all, even with caffeine. I usually take Advil (three and sometimes four at a time) with a Coke for bad headaches or migraine. If you take it at the beginning of a migraine it works so much better than waiting for the pain to get horrible. It is important to always have something on your stomach before taking asprin or Advil though.

Regular Member

Date Joined Jan 2008
Total Posts : 491
   Posted 6/23/2008 6:42 AM (GMT -6)   
Maxalt works great for migraines. But I have been having too many of them, so I may be put on something else....

My previous primary doc had me taking ibuprofen for my heavy periods, but my new primary does not want me taking any ibuprofen at all. Some docs think if you just take a little, once in a while it's okay, and others think if there's a problem you shouldn't take it at all. If you have a lot of bleeding or if you aren't feeling well, I would discuss other options, like migraines meds, with your doctor.
Live for today, for tomorrow you might just get hit by a semi.

Veteran Member

Date Joined Mar 2006
Total Posts : 2670
   Posted 6/23/2008 10:25 AM (GMT -6)   
All I take is Tylenol. I do get a bad migraine a few times a year, and that's when they give me Vicodin. Thankfully I don't get those very often (blood pressure meds keeps them at bay). But no, NO NSAIDS!
I was once taking aspirin often for stress headaches I was getting at work. I had no idea I had Crohn's yet. But yeah, I ended up with a sever GI bleed. Four days in the hospital, 2 colonoscopies (along with other tests). Ended up losing over half of all the blood in my body. No NSAID is worth that for me. I steer clear.

Diagnosed with Crohn's Disease 2/06 after sever GI bleed. Has been suffering since 1998. History of rectal fistula and gallbladder removal. Currently taking Prednisone: tapered to 15 mg *eek*, Asacol, Questran, Toprol XL (for high blood pressure).

Post Edited (Jen77) : 6/23/2008 9:30:30 AM (GMT-6)

New Member

Date Joined Sep 2010
Total Posts : 15
   Posted 9/26/2010 3:07 AM (GMT -6)   
so, we should basically only take acetaminophin? i've been taking Tylenol, had bleeding when i was talking ibuprofen (before i was diagnosed)..haven't tried anything else.

Elite Member

Date Joined Apr 2005
Total Posts : 14995
   Posted 9/26/2010 9:13 AM (GMT -6)   
Yes only acetaminaphin is all we are allowed, as the others do cause us to bleed. FYI, This is a really old post. I might suggest you start a new post in the future as these older posts are usually not responded to as folks tend to think they already answered it. Good luck!
Gail*Nanners* Co-Moderator for Crohns Disease 
Crohn's Disease for over 34 years. Currently on Asacol, Prilosec, Estrace, Prinivil, Diltiazem, Percoset prn for pain, Zofran, Phenergan, Probiotics, Calcium, Vit D, and Xanax prn. Resections in 2002 & 2005. Also diagnosed w/ Fibromyalgia, Osteoarthritis, & Anxiety. Currently my Crohns is in remission, but my joints are going crazy!
*Every tomorrow has two handles.  We can take hold of it by the handle of anxiety, or by the handle of faith"*

Veteran Member

Date Joined Sep 2006
Total Posts : 2527
   Posted 9/26/2010 5:59 PM (GMT -6)   
Excedrine tension headache is the ONLY one we with IBD should take and that is if you can tolerate caffeine, this excedrine is Tylenol and caffeine only no aspirin
Dx with Crohn's 1987, symptoms as early as 1984.
Temp iliostomy February 2007, reversed June 2007, Ovarian cysts, migraines, allergies (incl food allergies) , oral allergy syndrome (diff than true food allergies), Asthma, Gall Bladder removed 1999, Inguenal hernia 1987

Veteran Member

Date Joined Dec 2005
Total Posts : 1768
   Posted 9/26/2010 8:36 PM (GMT -6)   
I think what you have to think about and consider is how your crohn's reacts. I've never had bleeding problems with my crohn's and I take aspirin (because of clots) daily. I also have talked to my GI because I have a hand injury that isn't responding to steroid shots, so I'm taking a rx anti-inflammatory. When I talked to her, she said that since my crohn's isn't currently active and I don't have bleeding problems, it might cause a flare, but it's up to me whether or not I choose to take them.

Keep in mind, I know I've NEVER had bleeding problems with my crohn's, so it's not as risky for me.

Oh, and she also told me when I first started going to her that occasional use isn't too terrible, and I shouldn't suffer with something like a migraine or menstrual cramps for fear of taking an NSAID.
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