In terms of toxicity, both Remicade and Humira have a long list of potential side effects. Most of the potential side effects are similar because both drugs work to inhibit the tumor necrosing factor. You are correct that their components are different but their action is very similar. I am not sure why the nurse made the statement she did. Many people start out on Humira now due to the time constraints of doing Remicade infusions every 6-8 weeks.
People who find that Remicade begins to lose effectiveness have successfully switched to Humira. There is a caveat that goes with this statement. A rather large percentage of people that have reacted negatively to Remicade find that Humira either does not provide relief for them or that they have a reaction to the Humira too.
Humira's immunosuppressant capabilities might be greater for YOU if Remicade has lost its efficacy. There is also a segment of the population that just do not respond to anti-TNF meds like Remicade and Humira. These people find neither drug provides any reduction in symptoms. So how a new medication will work for you depends entirely on your body's make-up. We are all so very different and respond accordingly.
I hope you and your GI can talk through your problems, especially the fact that you are not getting relief from Remicade and make a decision that works well for you.
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CD, Ankylosing Spondylitis, lupus, small fiber peripheral neuropathy, avascular necrosis, peripheral artery disease, degenerative disc disease, and a host of other medical problems.