Anyone have a log in to read this article?

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FitzyK23
Veteran Member


Date Joined May 2005
Total Posts : 4219
   Posted 6/27/2008 10:51 AM (GMT -7)   
 
The related articles listed in the lower right look interesting too.
26 Year old married female law student (last year!!). Diagnosed w/ CD 4 years ago, IBS for over 10 years before that, which was probably the CD. I am sort of lactose intollerant too but can handle anything cultured and do well w/ lactose pills and lactaid. For crohns I am currently on Pentasa 4 pills/4x day and hysociamine prn. I also have bad acid reflux and have been on PPI's since age 13. I have been through prilosec, prevacid, and nexium. Currently I am on Protonix in the morning and Zantac at night. I also take a birth control pill to allow some fun in my life.


belleenstein
Veteran Member


Date Joined Feb 2007
Total Posts : 1010
   Posted 6/27/2008 11:01 AM (GMT -7)   
Hi Fitzy: The article is from 2004. There are much more current research papers regarding 5-ASA compounds and their effectiveness in treating crohn's. The latest research seems to suggest that it has a very limited usefulness in managing crohn's as a maintenance drug, especially crohn's in the small bowel. Also, this is a .com site which almost surely means it is commercial in nature. Probably sponsored by pharmaceuticals. Doesn't mean the information is not useful, just that you have to be careful to balance it against other sources. I like Pubmed -- medline as a source. Even with these articles, you have to be careful because drug companies have perverted the research community and it is sometimes difficult to know where researchers are getting their funding.
Belleenstein:

30+ years living with Crohn's.


FitzyK23
Veteran Member


Date Joined May 2005
Total Posts : 4219
   Posted 6/27/2008 11:19 AM (GMT -7)   
Thanks - pentasa is very successful for me and I was hoping that this article would address whether the other ASA's would be as helpful. I guess I know part of the answer is no because Asacol really didn't help me that much. I was just curious if the research agreed w/ my life experience or not. I also noticed they seperated their sections on UC and crohns and I was curious to read what the different suggestions were in prescribing.

The reason for the .com may be because the website that charges to read the article is for profit. For example lexis and westlaw are all very reputable legal research sites but they are for law firms to use for profit not just for educational use for the general public. I am sure in the medical world there are extensive databases storing research that expect to make a profit off those that are interested in reading it.

When I wrote my major research paper last year my library had to order a few journal articles from psych websites to avoid me having to pay an arm and a leg for them.
26 Year old married female law student (last year!!). Diagnosed w/ CD 4 years ago, IBS for over 10 years before that, which was probably the CD. I am sort of lactose intollerant too but can handle anything cultured and do well w/ lactose pills and lactaid. For crohns I am currently on Pentasa 4 pills/4x day and hysociamine prn. I also have bad acid reflux and have been on PPI's since age 13. I have been through prilosec, prevacid, and nexium. Currently I am on Protonix in the morning and Zantac at night. I also take a birth control pill to allow some fun in my life.


Nanners
Elite Member


Date Joined Apr 2005
Total Posts : 14995
   Posted 6/27/2008 11:28 AM (GMT -7)   
You know Fitzy I think with the 5-ASA's they work for some and not for others. I use to successfully use Pentasa (and Pred) to control my flares and get back into remission before any of my resections. But since my resections, my Crohns is well controlled with Asacol. I know that Crohnie Too has success with Pentasa. So I personally just think it depends on the person. I and if I am not mistaken C2 have the stricturing types of Crohns. I don't know if that makes any difference or not. JMHO
Been living with Crohn's Disease for 32 years.  Currently on Asacol, Prilosec 60 mg, Estrace, Prinivil, Diltiazem, Percoset prn for pain and Calcium.  Resections in 2002 and 2005.  Recently diagnosed with Fibromyalgia and doing tests to see if I have Inflammatory Arthritis or AS.


FitzyK23
Veteran Member


Date Joined May 2005
Total Posts : 4219
   Posted 6/27/2008 11:30 AM (GMT -7)   
I use it as a maintenence med to avoid flares and so far when I do hit a flare entocort has worked (knock on wood). I had cut back my pentasa a couple months ago but started feeling lousy so I went back up to the full dose and am sticking to it!
26 Year old married female law student (last year!!). Diagnosed w/ CD 4 years ago, IBS for over 10 years before that, which was probably the CD. I am sort of lactose intollerant too but can handle anything cultured and do well w/ lactose pills and lactaid. For crohns I am currently on Pentasa 4 pills/4x day and hysociamine prn. I also have bad acid reflux and have been on PPI's since age 13. I have been through prilosec, prevacid, and nexium. Currently I am on Protonix in the morning and Zantac at night. I also take a birth control pill to allow some fun in my life.

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