This is the first time Ive come to this site. We have a 5 yr old son with many medical issues and has had GI issues/Reflux/Pain/chronic diarrhea all his life. He never took to solid foods as a baby and is nearly 100% tube fed. He also has been diagnosed with a unspecified Myopathy thru a muscle biopsy.
Im hoping someone here can help me with his results.
He had the Prometheus IBD serology 7 test done.
Here's the results: Pattern NOT consistent with IBD.
Patient Assay Information:
ASCA IgA: <12.0 EU/ml
ASCA IgG: <12.0 EU/ml
Anti-OmpC IgA: 0.3 EU/ml---Is this also high? and out of range?
Anti-CBir1: 90.4 EU/ml---This one IS out of range.
Auto Antibody: <12.1 EU/ml
IFA Perinuclear Pattern: Not Detected --Any idea what this is?
DNAse Sensitivity: Not Detected --Any idea what this is?
J's Colonoscopy Biopsy results showed many Eosinophils in the Colon and Small bowel. He also has a lot of inflammaton seen on an Upper GI/small bowel foolow thru xray. NO neutrophils were found and his colon looked very good visually. When they took the biopsies though, he bled more than normal, fragile walls.
After getting these results, we were told he DID NOT have Crohns or at least its reasonble to say we were looking at a Eosinophilic disease because of the eos found. We were told he had Eosinophilc enteritis/coiltis.
BUT what does the high numbers mean in the serology report? Mostly the Anti-CBir1? Is that a high number? And what does it mean if the critical markers of Crohns numbers were within range but this one not?
Can you have lots of eos found in both the colon and small bowel with Crohns as well? OR does this indicate only Eosinophilic disease? Can you have BOTH the Crohns and a Eosinophilic disease?? How common is it to find eos with Crohns?
Im so frustrated with all this. His formula was changed to Elecare and we removed almost everything from his diet. He's now scheduled to have a capsule endo done to see whats going on in the intsetines that the Drs cant get to from either upper or the lower scopes.
Anyone have experience with the capsule endo?
If anyone can help make out what these numbers mean, I would really appreciate your thoughts.
Thanks so much.