i increased from 25 to 50 and now to 75mgs (i weigh 106lbs) so i am kind of on a high dose for my size. after several months at 50mgs and my tpmt levels were low, i increased to 75mgs, had my tpmt checked again a few months later and barely had a change. i am still about 1/3 away from even hitting the beneficial zone :/ also, you should ask your gi if you still need to take pentasa. my gi said once you hit the point of 6mp, pentasa isn't much help. it's so expensive with little results, at least, that's what i found in my case!
best of luck to you!
.: stephanie :.
33 y/o female diagnosed 8/8/7 with crohn's of the terminal ileum w/ stricture/scarring
meddies: 6mp, percocet, trazodone, ativan, iron, calcium, folic acid & some other vits