Stem Cells For CD

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

jim83
New Member


Date Joined Apr 2008
Total Posts : 9
   Posted 7/11/2008 5:06 AM (GMT -7)   
Check out the article in todays Ottawa Citizen (Canada) re person who had  a stem cell transplant for CD
 
 
 

AlwaysRosie
Veteran Member


Date Joined Jan 2005
Total Posts : 8616
   Posted 7/11/2008 6:41 AM (GMT -7)   
WOW!

In His Grip

AlwaysRosie           "We can't control the waves, but we can learn how to surf!!"

Psalms 139

Co-Moderator - Lupus Forum

UCTD, Inflammatory Arthritis, Diverticulosis, (recent dx - Sjogrens, Crohn’s 4/08)

Clickable Links:  Lupus Resources    Lupous.Org   Lupus Criteria (4 of 11)   Lupus Chapter Locator


Rider Fan
Veteran Member


Date Joined May 2008
Total Posts : 1445
   Posted 7/11/2008 2:39 PM (GMT -7)   
Nowhere in the article does it state that his CD is cured...
Dx'ed in 1999. No surgeries.

Current meds: 75 mg 6MP. 20mg prednisone.  Udo's Choice Probiotics (30 billion).


Rider Fan
Veteran Member


Date Joined May 2008
Total Posts : 1445
   Posted 7/11/2008 5:16 PM (GMT -7)   
I didn't realize that it was your opinion, it wasn't clear in your statement, my apologies. Unfortunately, the book is still out in whether stem cells will bring a cure.
Dx'ed in 1999. No surgeries.

Current meds: 75 mg 6MP. 20mg prednisone.  Udo's Choice Probiotics (30 billion).


ivy6
Elite Member


Date Joined Sep 2005
Total Posts : 10404
   Posted 7/11/2008 5:58 PM (GMT -7)   
Brilliant! Thanks for posting this.
Co-Moderator Crohn's Forum.


abseeley
Regular Member


Date Joined Jun 2008
Total Posts : 49
   Posted 7/11/2008 6:22 PM (GMT -7)   
I got this article in my paper today too, in my citizen

pb4
Elite Member


Date Joined Feb 2004
Total Posts : 20576
   Posted 7/11/2008 6:54 PM (GMT -7)   
"Cure" is such a touchy word still eh...but in the article it does state keeping patients in remission for 20ish months (just going by my crappy memory) but that when patients flared again the severity and length of flare was quite a bit lower compared to before the stem cell therapy, so as I've said before we don't know what form of "cure" will actually come for us in the future, it may be stem cell injections once every couple of yrs for the rest of our lives to be the "cure".

:)
My bum is broken....there's a big crack down the middle of it!  LOL  :)


Reef08
Regular Member


Date Joined Dec 2005
Total Posts : 267
   Posted 7/11/2008 11:27 PM (GMT -7)   
An allogenic stem cell transplant, or bone marrow transplant, is a cure since your immune system is replaced by that of the donor thereby replacing the original defect. Of course this can cause more fatal side effects like graft vs. host disease. You won't be able to get the disease again however unless the donor's immune system has the same defect.

The procedure in this article is an autologous stem cell transplant in which your own immune system is regrown. You can develop the disease again if you are exposed to the original environmental trigger, since the new immune system has the original flaw.

JerryGarcia
Regular Member


Date Joined Feb 2008
Total Posts : 68
   Posted 7/12/2008 3:47 AM (GMT -7)   
Correct me if I'm wrong, but there are currently two types of stem cell treatment available.

1. A drug such as prochymal which contains adult stem cells is given as an infusion every so often to keep the patient in remission.

2. Stem cells are extracted from the patients marrow, chemo is then used to kill of the immune system and the stem cells are injected back in to form a new one. As far as I know this is very risky (although no one has had any complications as yet) and will offer more of a cure, whilst the prochymal is more of a maintenance therapy.
DX with UC Jan 07
Currently taking Colazide (allergic to Asacol and Pentasa) 2 a day
Also taking VSL3 X3 a day
Just started LDN 4.5mg


ivy6
Elite Member


Date Joined Sep 2005
Total Posts : 10404
   Posted 7/12/2008 5:29 AM (GMT -7)   
3. Four heavy infusions of chemotherapy, which is supposed to reboot the immune system. No actual infusion of stem cells, but my scientist mother said it worked on the same principles as the two treatments mentioned by Jerry. Apparently it's had success in treating MS, and is being tested on Crohn's and a few other auto-immune illnesses.
Co-Moderator Crohn's Forum.


GURU77
New Member


Date Joined Jul 2008
Total Posts : 11
   Posted 7/12/2008 5:30 AM (GMT -7)   
I tried a couple stem cell places and they both said they were not ready to treat crohns, but at least there's some hope of a cure hopefully in our lifetime.

ivy6
Elite Member


Date Joined Sep 2005
Total Posts : 10404
   Posted 7/12/2008 5:41 AM (GMT -7)   
Here's a link to the treatment (#3) I mentioned:

http://cat.inist.fr/?aModele=afficheN&cpsidt=14537536
Co-Moderator Crohn's Forum.


abseeley
Regular Member


Date Joined Jun 2008
Total Posts : 49
   Posted 7/12/2008 9:12 PM (GMT -7)   
this is pretty interesting and i live 10 minutes from ottawa (where this article came from) I wonder if I could maybe sneak in on a clinical trial or something :P

Reef08
Regular Member


Date Joined Dec 2005
Total Posts : 267
   Posted 7/13/2008 5:44 PM (GMT -7)   
ivy6 said...
Here's a link to the treatment (#3) I mentioned:

http://cat.inist.fr/?aModele=afficheN&cpsidt=14537536


There's a drug called Revimmune (it's actually pulsed high-dose cyclosphamide) being used for MS off-label at John Hopkins. The results are pretty amazing so far. They've patented it for all autoimmune diseases, so the trials for it should be starting for Crohn's maybe in year or two.

ivy6
Elite Member


Date Joined Sep 2005
Total Posts : 10404
   Posted 7/13/2008 5:59 PM (GMT -7)   
Yep, that's the one I was talking about. Thanks, Reef. I couldn't remember its name. Good to know it's soon to be in trial.
Co-Moderator Crohn's Forum.


MMMNAVY
Veteran Member


Date Joined Jul 2006
Total Posts : 6927
   Posted 7/13/2008 7:34 PM (GMT -7)   
I certainly would not call it a "cure" yet. But then again I have a very strict criteria for that word.
Forum Co-moderator - Crohn's Disease
We will find a way, or make one.-Hannibal (crossing the Alps in the 15th Century on war elephants) 
Make sure your suffering has meaning...-?
All suggestions/options/opinions are caveated with please consult with your local health care provider...

New Topic Post Reply Printable Version
Forum Information
Currently it is Thursday, December 08, 2016 11:15 AM (GMT -7)
There are a total of 2,734,771 posts in 301,246 threads.
View Active Threads


Who's Online
This forum has 151352 registered members. Please welcome our newest member, dillon91750.
324 Guest(s), 11 Registered Member(s) are currently online.  Details
ResilienceR, Hol1979, TOOTY, tickcheckguy, 1000Daisies, Girlie, smlafleur, ChickNorris, fenway17, blksteeda, beachbum50


Follow HealingWell.com on Facebook  Follow HealingWell.com on Twitter  Follow HealingWell.com on Pinterest
Advertisement
Advertisement

©1996-2016 HealingWell.com LLC  All rights reserved.

Advertise | Privacy Policy & Disclaimer