I have some questions for everybody who has taken either Imuran or 6MP.
I started imuran a few months ago. I weigh about 145 pounds so we figured my target dose would be about 150mgs/day. I wanted to ramp up slowly, so I started at 50mgs for the first several weeks.
I had no problems, no side effects, and my blood work was always normal, so after a few weeks I went to 100mgs/day.
Soon after that, I started getting nauseous, not enough that I was vomiting, but enough that it was very difficult to eat and I was feeling *worse*, not better, than before. My blood tests were still good.
I tried taking it in the morning, at night, split dose morning/night, with food, etc, and nothing seemed to help.
I backed down to 50mgs and within a few days felt better again. So I tried to ramp up even slower. I went up to 75mgs for six weeks, and had a small amount of nausea, but it was mild and tolerable. After six weeks, I started 100mgs and within a couple of days, I was very nauseous and unable to eat again.
So, my question: It seems I can't tolerate Imuran because of nausea, even though my blood work was good. Any other tricks to help with the nausea before I give up on Imuran for good? Or, has anybody not been able to tolerate Imuran because of nausea, but then tried 6MP and been able to tolerate it better? Or, vice versa, been able to tolerate imuran but not 6MP?
I'm thinking of trying 6MP next.
Thanks for any experiences you can share.