I have had this same experience with acne while taking entocort in the past. I just recently had to begin entocort again due to a flare and like you have patches of acne all over my face. It also hurts. I know it has to be the entocort cause each time I've taken it this has happened and all other meds are the same & have been on a long time with the exception of just recently starting Humira. It seems to get even worse at night and it also hurts. Just can't wait to wean down.